Personal profile
Areas of expertise
Molecular and Cellular Biology, Cancer Multidrug Resistance Mechanisms, Non-Clinical Drug Development, Pharmacogenomics, ABC Transporters.
External responsibilities
- Non-Clinical Expert: Federal Agency for Medicines and Health Products.
- Faculty Member: F1000Prime. Pharmacology & Drug Discovery: Cancer Therapeutics.
- Jury Member: FRIA LS3, Jury 1.
- Jury Member: Fund Simon Bauvin, Christian Lispet, Robert Brancart and Denise Raes created to support medical scientific research into childhood cancer in the French Community of Belgium (King Baudoin Foundation).
Awards
- Adrien Bauchau Award 2005 for PhD Thesis
- NCI Director’s 2010 Intramural Career Development Innovation Award
Education/Academic qualification
Doctor of Science, Microarray-based detection for multidrug resistance in human by expression profiling of ABC transporter genes and for small B-cell non Hodgkin's lymphoma characterization, University of Namur
Award Date: 25 Apr 2006
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Collaborations and top research areas from the last five years
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Investigation of physiological substrates and functional properties of the human full and half ABC transporters, ABCB5FL and ABCB5β, potential targets in cancer therapy
POSKIN, L. (PI), Michaux, C. (Supervisor) & Gillet, J.-P. (CoI)
1/11/24 → 31/12/26
Project: Research
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Improve the diagnosis and treatment of esophageal cancer by identifying circulating tumour DNA and characterizing genome alterations leading to treatment failure.
Gillet, J.-P. (PI), Laes, J. F. (PI) & LEFEVRE, S. (PI)
1/04/20 → 31/12/20
Project: Research
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Erasmus+ICM: PROJECT FOR HIGHER EDUCATION STUDENT AND STAFF MOBILITY BETWEEN PROGRAMME COUNTRIES AND PARTNER COUNTRIES
Gillet, J.-P. (PI)
1/06/17 → 28/07/19
Project: Research
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DualChip Human Low Grade B-Cell Lymphoma: a specialized Low Density DNA Microarray for the differential diagnostic of SMALL B-Cell non-Hodgkin¿s Lymphoma
Remacle, J. (PI) & Gillet, J.-P. (Researcher)
15/09/03 → 31/03/06
Project: PHD
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MDRchips: Development of a DNA microarray for the expression study of genes involved in Multi Drug Resistances in Leukemia and solid tumors
Remacle, J. (PI) & Gillet, J.-P. (Researcher)
1/09/00 → 20/12/00
Project: Research
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Could venom-derived therapeutics resolve treatment resistance in refractory EAC?
Freuville, L., Matthys, C., Gilliaux, Q., D’Hondt, L. & Gillet, J. P., 2026, (Accepted/In press) In: Trends in Molecular Medicine.Research output: Contribution to journal › Review article › peer-review
Open Access -
Abcb5-deficient mice show a subtle, pleiotropic phenotype indicating a role for this transporter in intermediary metabolism
Gillet, J. P., Gerard, L., Vieira, W., Fourrez, M., Gaudray, F., Rathkolb, B., Rozman, J., Klein-Rodewald, T., Becker, L., Aguilar-Pimentel, A., Horsch, M., Spielmann, N., Prehn, C., Bihin, B., Beckers, J., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Southon, E. & Tessarollo, L. & 2 others, , 17 Oct 2025, In: iScience. 28, 10, 113617.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9
Gerard, L., Duvivier, L., Fourrez, M., Salazar, P., Sprimont, L., Xia, D., Ambudkar, S. V., Gottesman, M. M. & Gillet, J. P., Feb 2024, In: The Journal of Biological Chemistry. 300, 2, 105594.Research output: Contribution to journal › Article › peer-review
Open AccessFile51 Downloads (Pure) -
The uniqueness of ABCB5 as a full transporter ABCB5FL and a half-transporter-like ABCB5β
Gerard, L. & Gillet, J. P., 2024, In: Cancer Drug Resistance. 7, 29.Research output: Contribution to journal › Review article › peer-review
Open AccessFile44 Downloads (Pure) -
Venom-derived peptides for breaking through the glass ceiling of drug development
Freuville, L., Matthys, C., Quinton, L. & Gillet, J. P., 2024, In: Frontiers in Chemistry. 12, 1465459.Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Downloads (Pure)
Prizes
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Adrien Bauchau Fund for Young Researcher
Gillet, J.-P. (Recipient), 2005
Prize: Prize (including medals and awards)
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Eppendorf Array Technologies Research Fellowship
Gillet, J.-P. (Recipient), 2004
Prize: Fellowship awarded competitively
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Erasmus European Mobility Grant
Gillet, J.-P. (Recipient), 1999
Prize: Fellowship awarded competitively
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Activities
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Symposium NARILIS “From the molecule to the drug”
Gillet, J.-P. (Speaker)
21 Feb 2015Activity: Participating in or organising an event types › Participation to a Symposium, a study Day
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University of Liverpool, The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine
Gillet, J.-P. (Invited speaker)
5 Nov 2013Activity: Talk or presentation types › Invited talk
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13rd French-Belgian Annual ABC meeting
Gillet, J.-P. (Invited Speaker)
18 Oct 2013Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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Gordon Research Conference
Gillet, J.-P. (Invited Speaker)
22 Mar 2013 → 27 Mar 2013Activity: Participating in or organising an event types › Participation in conference
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9th Annual North American ABC Genetic Workshop
Gillet, J.-P. (Invited Speaker)
27 Sept 2012 → 28 Sept 2012Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Thesis
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Le promoteur du gène reelin de la souris
Gillet, J.-P. (Author), Goffinet, A. (Supervisor), 2000Student thesis: Degree types › Degree in Biology
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Microarray-based detection for multidrug resistance in human by expression profiling of ABC transporter genes and for small B-cell non Hodgkin's lymphoma characterization: Damier à ADN de faible densité pour la détection des gènes ABC transporteurs dans les tumeurs humaines et pour la caractérisation des lymphomes non Hodgkiniens à petites cellules B
Gillet, J.-P. (Author), Remacle, J. (Supervisor), Michiels, C. (Jury), Herin, M. (Co-Supervisor), Bosly, A. (Jury), Efferth, T. (Jury) & MOLINA, T. (Jury), 25 Apr 2006Student thesis: Doc types › Doctor of Sciences
Press/Media
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Studies from University of Namur Reveal New Findings on Clinical Oncology (Could venom-derived therapeutics resolve treatment resistance in refractory EAC?)
14/04/26
1 item of Media coverage
Press/Media: Expert Comment
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New Life Sciences Study Findings Recently Were Reported by Researchers at University of Namur (Abcb5-deficient mice show a subtle, pleiotropic phenotype indicating a role for this transporter in intermediary metabolism)
Bihin, B., Gillet, J.-P. & Fourrez, M.
12/11/25
1 item of Media coverage
Press/Media: Expert Comment
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Research Data from University of Namur Update Understanding of Biomarkers (The b Isoform of Human ATP-Binding Cassette B5 Transporter, ABCB5b, Localizes to the Endoplasmic Reticulum)
Albert, M., Boonen, M. & Gillet, J.-P.
29/11/23
1 item of Media coverage
Press/Media: Expert Comment