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2020

Chiral Resolution of RS-Oxiracetam upon Cocrystallization with Pharmaceutically Acceptable Inorganic Salts

Shemchuk, O., Song, L., Tumanov, N., Wouters, J., Braga, D., Grepioni, F. & Leyssens, T., 1 Apr 2020, In : Crystal Growth and Design. 20, 4, p. 2602-2607 6 p.

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Open Access

Complex mineralogical-geochemical sequences and weathering events in the supergene ore of the Cu–Co Luiswishi deposit (Katanga, D.R. Congo)

Fontaine, L., De Putter, T., Bernard, A., Decrée, S., Cailteux, J., Wouters, J. & Yans, J., Jan 2020, In : Journal of African Earth Sciences. 161, 103674.

Research output: Contribution to journalArticle

Identification and Repurposing of Trisubstituted Harmine Derivatives as Novel Inhibitors of Mycobacterium tuberculosis Phosphoserine Phosphatase

Pierson, E., Haufroid, M., Gosain, T. P., Chopra, P., Singh, R. & Wouters, J., 19 Jan 2020, In : Molecules. 25, 2, 17 p., 415.

Research output: Contribution to journalArticle

Open Access

Improving nefiracetam dissolution and solubility behavior using a cocrystallization approach

Buol, X., Robeyns, K., Garrido, C. C., Tumanov, N., Collard, L., Wouters, J. & Leyssens, T., Jul 2020, In : Pharmaceutics. 12, 7, p. 1-14 14 p., 653.

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Merocyanines in a Halogen-Bonded Network Involving Inorganic Building Blocks

Seiler, V. K., Tumanov, N., Robeyns, K., Champagne, B., Wouters, J. & Leyssens, T., 5 Feb 2020, In : Crystal Growth and Design. 20, 2, p. 608-616 9 p.

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Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting D-alanyl-D-alanine ligase in bacterio

Ameryckx, A., Pochet, L., Wang, G., Yildiz, E., Saadi, B. E., Wouters, J., Van Bambeke, F. & Frédérick, R., 15 Aug 2020, In : European Journal of Medicinal Chemistry. 200, 112444.

Research output: Contribution to journalArticle

Selective recognition of small hydrogen bond acceptors by a calix[6]arene-based molecular container

Lavendomme, R., Desroches, F., Moerkerke, S., Topić, F., Wouters, J., Rissanen, K., Luhmer, M. & Jabin, I., 2 Jan 2020, In : Supramolecular Chemistry. 32, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

2019

A coloring tool for spiropyrans: Solid state metal-organic complexation: Versus salification

Seiler, V. K., Robeyns, K., Tumanov, N., Cinčić, D., Wouters, J., Champagne, B. & Leyssens, T., 10 Jul 2019, In : CrystEngComm. 21, 33, p. 4925-4933 9 p.

Research output: Contribution to journalArticle

Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation

Spillier, Q., Vertommen, D., Ravez, S., Marteau, R., Thémans, Q., Corbet, C., Feron, O., Wouters, J. & Frédérick, R., 18 Mar 2019, In : Scientific Reports. 9, 1, 4737.

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Open Access

A Simple and Efficient Mechanochemical Route for the Synthesis of Salophen Ligands and of the Corresponding Zn, Ni, and Pd Complexes

Fusaro, L., Carletta, A., Dubois, J., Tumanov, N., Aprile, C., Wouters, J., Dalla Cort, A. & Leoni, L., 1 Jan 2019, In : Molecules. 24, 12, p. 2314 11 p., 2314.

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Identifying, Characterizing, and Understanding Nefiracetam in Its Solid State Forms: A Potential Antidementia Drug

Buol, X., Robeyns, K., Tumanov, N., Wouters, J. & Leyssens, T., 1 Nov 2019, In : Journal of Pharmaceutical Sciences. 108, 11, p. 3616-3622 7 p.

Research output: Contribution to journalArticle

Molecular Recognition of Strong Acids by Using a 2-Ureido-4-Ferrocenyl Pyrimidine Receptor

Keszei, S. J., Balogh, S., Fehér, C., Nagy, L., Tumanov, N., Wouters, J., Lendvay, G. & Skoda-Földes, R., 17 Oct 2019, In : European Journal of Inorganic Chemistry. 2019, 38, p. 4095-4104 10 p.

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Open Access

New Insights into Photochromic Properties of N-Salicylideneaniline Derivatives Using a Cocrystal Engineering Approach

Mercier, G. M., Robeyns, K., Tumanov, N., Champagne, B., Wouters, J. & Leyssens, T., 2 Oct 2019, In : Crystal Growth & Design. 19, 10, p. 5544-5556 13 p.

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Open Access

Periodic DFT study of the effect of cocrystalisation on a N-salicylideneaniline molecular switch

Quertinmont, J., Leyssens, T., WOUTERS, JOHAN. & CHAMPAGNE, B., 19 Aug 2019, In : ChemPhysChem. 20, 19, p. 2434-2442

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Periodic DFT Study of the Effects of Co‐Crystallization on a N‐Salicylideneaniline Molecular Switch

Quertinmont, J., Leyssens, T., Wouters, J. & Champagne, B., 2 Oct 2019, ChemPhysChem, 20, 19, p. 2434-2442 1 p.

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Open Access
Open Access

Regio‐and Diastereoselective Functionalization of 3‐Amino‐hexahydrooxazoninones

Schurgers, B., Wouters, J., De Blieck, A., Van Lommen, G., Menet, C. & Verniest, G., 10 Jan 2019, In : European Journal of Organic Chemistry. 2019, 1, p. 36-40 5 p.

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Structural Analysis of d -Phenylglycinamide Salts Uncovers Potential Pitfalls in Chiral Resolution via Diastereomeric Salt Formation

Tumanova, N., Seiler, V., Tumanov, N., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 3 Jul 2019, In : Crystal Growth & Design. 19, 7, p. 3652-3659 8 p.

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Targeting the serine pathway: a promising approach against tuberculosis?

Haufroid, M. & Wouters, J., 1 Jun 2019, In : Pharmaceuticals. 12, 2, 66.

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Open Access
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2018

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting D-alanine-D-alanine ligase in bacterio

Ameryckx, A., Thabault, L., Pochet, L., Leimanis, S., Poupaert, J., Wouters, J., Joris, B., Van Bambeke, F. & Frederick, R., 5 Nov 2018, In : European journal of medicinal chemistry / Chimica therapeutica. 159, 5, p. 324-338 15 p.

Research output: Contribution to journalArticle

Open Access

Acidochromic spiropyran-merocyanine stabilisation in the solid state

Seiler, V. K., Callebaut, K., Robeyns, K., Tumanov, N., Wouters, J., Champagne, B. & Leyssens, T., 1 Jan 2018, In : CrystEngComm. 20, 24, p. 3318-3327 10 p.

Research output: Contribution to journalArticle

A Possible Infinite Number of Components in a Single Crystalline Phase: On the Isomorphism of Brivaracetam-Guest Molecules

Couvrat, N., Sanselme, M., Cartigny, Y., De Smet, F., Rome, S., Aerts, L., Quéré, L., Wouters, J. & Coquerel, G., 5 Sep 2018, In : Crystal Growth and Design. 18, 9, p. 4807-4810 4 p.

Research output: Contribution to journalArticle

Convenient one-pot formation of highly functionalized 5-bromo-2-aminothiazoles, potential endocannabinoid hydrolase MAGL inhibitors

Prevost, J. R. C., Kozlova, A., Es Saadi, B., Yildiz, E., Modaffari, S., Lambert, D. M., Pochet, L., Wouters, J., Dolušić, E. & Frédérick, R., 5 Dec 2018, In : Tetrahedron Letters. 59, 49, p. 4315-4319 5 p.

Research output: Contribution to journalArticle

Direct Access by Mechanochemistry or Sonochemistry to Protonated Merocyanines: Components of a Four‐State Molecular Switch

Colaço, M., Carletta, A., Van Gysel, M., Robeyns, K., Tumanov, N. & Wouters, J., 2 Jul 2018, In : ChemistryOPEN. 7, 7, p. 520-526 7 p.

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Direct Orange 34 dye fixation by modified kaolin

Chargui, H., Hajjaji, W., Wouters, J., Yans, J. & Jamoussi, F., 1 Jan 2018, In : Clay Minerals. 53, 2, p. 271-287 17 p.

Research output: Contribution to journalArticle

Open Access
Open Access
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Exploring polymorphism and stoichiometric diversity in naproxen/proline cocrystals

Tumanova, N., Tumanov, N., Fischer, F., Morelle, F., Ban, V., Robeyns, K., Filinchuk, Y., Wouters, J., Emmerling, F. & Leyssens, T., 1 Jan 2018, In : CrystEngComm. 20, 45, p. 7308-7321 14 p.

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Halogen-bonded cocrystals of N -salicylidene Schiff bases and iodoperfluorinated benzenes: Hydroxyl oxygen as a halogen bond acceptor

Carletta, A., Zbačnik, M., Vitković, M., Tumanov, N., Stilinović, V., Wouters, J. & Cinčić, D., 1 Jan 2018, In : CrystEngComm. 20, 36, p. 5332-5339 8 p.

Research output: Contribution to journalArticle

Morphine, a potential inhibitor of myeloperoxidase activity

Nyssen, P., Mouithys-Mickalad, A., Minguet, G., Sauvage, E., Wouters, J., Franck, T. & Hoebeke, M., 1 Oct 2018, In : Biochimica et Biophysica Acta - General Subjects. 1862, 10, p. 2236-2244 9 p.

Research output: Contribution to journalArticle

Opening Pandora’s Box: Chirality, Polymorphism, and Stoichiometric Diversity in Flurbiprofen/Proline Cocrystals

Tumanova, N., Tumanov, N., Robeyns, K., Fischer, F., Fusaro, L., Morelle, F., Ban, V., Hautier, G., Filinchuk, Y., Wouters, J., Leyssens, T. & Emmerling, F., 4 Jan 2018, In : Crystal Growth & Design. 18, 2, p. 954-961 8 p.

Research output: Contribution to journalArticle

Playing with Isomerism: Cocrystallization of Isomeric N-Salicylideneaminopyridines with Perfluorinated Compounds as Halogen Bond Donors and Its Impact on Photochromism

Carletta, A., Zbačnik, M., Van Gysel, M., Vitković, M., Tumanov, N., Stilinović, V., Wouters, J. & Cinčić, D., 7 Nov 2018, In : Crystal Growth and Design. 18, 11, p. 6833–6842 10 p.

Research output: Contribution to journalArticle

Templated Chromophore Assembly on Peptide Scaffolds: A Structural Evolution

Rocard, L., Wragg, D., Jobbins, S. A., Luciani, L., Wouters, J., Leoni, S. & Bonifazi, D., 26 Oct 2018, In : Chemistry - A European Journal. 24, 60, p. 16136-16148 13 p.

Research output: Contribution to journalArticle

The Use of Switchable Polarity Solvents for the Synthesis of 16‐Arylidene Steroids via Claisen–Schmidt Condensation

Ispán, D., Szánti-Pintér, E., Papp, M., Wouters, J., Tumanov, N., Balázs Zsirka, B., Gömöry, Á., Kollár, L. & Skoda-Földes, R., 29 Jun 2018, In : European Journal of Organic Chemistry. 2018, 24, p. 3236-3244 9 p.

Research output: Contribution to journalArticle

Open Access
2017

A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis

Carvalho, A., Chu, J., Meinguet, C., Kiss, R., Vandenbussche, G., Masereel, B., Wouters, J., Kornienko, A., Pelletier, J. & Mathieu, V., 15 Jun 2017, In : European Journal of Pharmacology. 805, p. 25-35 11 p.

Research output: Contribution to journalArticle

Open Access

A structural analysis of spiropyran and spirooxazine compounds and their polymorphs

Seiler, V. K., Tumanov, N., Robeyns, K., Wouters, J., Champagne, B. & Leyssens, T., 13 Mar 2017, In : Crystals. 7, 3, 84.

Research output: Contribution to journalArticle

Open Access

A Study of Fasoracetam's Solid State Forms: A Potential Anti-Alzheimer Pharmaceutical

Harmsen, B., Robeyns, K., Wouters, J. & Leyssens, T., 1 May 2017, In : Journal of Pharmaceutical Sciences. 106, 5, p. 1317-1321 5 p.

Research output: Contribution to journalArticle