If you made any changes in Pure these will be visible here soon.

Research Output

Article

Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase

Wouters, J., Oudjama, Y., Ghosh, S., Stalon, V., Droogmans, L. & Oldfield, E., 19 Mar 2003, In : Journal of the American Chemical Society. 125, 11, p. 3198-3199 2 p.

Research output: Contribution to journalArticle

Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria

Sinnaeve, D., Michaux, C., Van hemel, J., Vandenkerckhove, J., Peys, E., Borremans, F. A. M., Sas, B., Wouters, J. & Martins, J. C., 23 May 2009, In : Tetrahedron. 65, 21, p. 4173-4181 9 p.

Research output: Contribution to journalArticle

Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics

De Ruyck, J., Rothman, S. C., Poulter, C. D. & Wouters, J., 23 Dec 2005, In : Biochemical and Biophysical Research Communications. 338, 3, p. 1515-1518 4 p.

Research output: Contribution to journalArticle

Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templates

Muccioli, G. G., Fazio, N., Scriba, G. K. E., Poppitz, W., Cannata, F., Poupaert, J. H., Wouters, J. & Lambert, D. M., 12 Jan 2006, In : Journal of Medicinal Chemistry. 49, 1, p. 417-425 9 p.

Research output: Contribution to journalArticle

Substituted 5,5′-diphenyl-2-thioxoimidazolidin-4-one as CB 1 cannabinoid receptor ligands: Synthesis and pharmacological evaluation

Muccioli, G. G., Martin, D., Scriba, G. K. E., Poppitz, W., Poupaert, J. H., Wouters, J. & Lambert, D. M., 7 Apr 2005, In : Journal of Medicinal Chemistry. 48, 7, p. 2509-2517 9 p.

Research output: Contribution to journalArticle

Substrate binding and catalytic mechanism of class B β-lactamases: A molecular modelling study

Prosperi-Meys, C., Wouters, J., Galleni, M. & Lamotte-Brasseur, J., 1 Dec 2001, In : Cellular and Molecular Life Sciences. 58, 14, p. 2136-2143 8 p.

Research output: Contribution to journalArticle

Supramolecular Assistance for the Selective Demethylation of Calixarene-Based Receptors

Danjou, P. E., De Leener, G., Cornut, D., Moerkerke, S., Mameri, S., Lascaux, A., Wouters, J., Brugnara, A., Colasson, B., Reinaud, O. & Jabin, I., 15 May 2015, In : Journal of Organic Chemistry. 80, 10, p. 5084-5091 8 p.

Research output: Contribution to journalArticle

Supramolecular Wiring of Benzo-1,3-chalcogenazoles through Programmed Chalcogen Bonding Interactions

Kremer, A., Fermi, A., Biot, N., Wouters, J. & Bonifazi, D., 11 Apr 2016, In : Chemistry (Weinheim an der Bergstrasse, Germany). 22, 16, p. 5665-5675 11 p.

Research output: Contribution to journalArticle

Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: New structural insight into the HIV-1 integrase inhibition

Vandurm, P., Guiguen, A., Cauvin, C., Georges, B., Le Van, K., Michaux, C., Cardona, C., Mbemba, G., Mouscadet, J. F., Hevesi, L., Van Lint, C. & Wouters, J., 1 May 2011, In : European Journal of Medicinal Chemistry. 46, 5, p. 1749-1756 8 p.

Research output: Contribution to journalArticle

Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles

Moineaux, L., Laurent, S., Reniers, J., Dolusic, E., Galleni, M., Frère, J-M., Masereel, B., Frédérick, R. & Wouters, J., 1 Aug 2012, In : European Journal of Medicinal Chemistry. 54, p. 95-102 8 p.

Research output: Contribution to journalArticle

Open Access
File
139 Downloads (Pure)

Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core

Frédérick, R., Dumont, W., Ooms, F., Aschenbach, L., Van Der Schyf, C. J., Castagnoli, N., Wouters, J. & Krief, A., 15 Jun 2006, In : Journal of Medicinal Chemistry. 49, 12, p. 3743-3747 5 p.

Research output: Contribution to journalArticle

Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxoimidazolidin-4-ones: Characterization of new CB 1 cannabinoid receptor inverse agonists/antagonists

Muccioli, G. G., Wouters, J., Charlier, C., Scriba, G. K. E., Pizza, T., Di Pace, P., De Martino, P., Poppitz, W., Poupaert, J. H. & Lambert, D. M., 9 Feb 2006, In : Journal of Medicinal Chemistry. 49, 3, p. 872-882 11 p.

Research output: Contribution to journalArticle

Synthesis and anticonvulsant activity of N,N-phthaloyl derivatives of central nervous system inhibitory amino acids

Usifoh, C. O., Lambert, D. M., Wouters, J. & Scriba, G. K. E., 3 Dec 2001, In : Archiv der Pharmazie. 334, 10, p. 323-331 9 p.

Research output: Contribution to journalArticle

Synthesis and Bioactivity of β-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase

Chofor, R., Sooriyaarachchi, S., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C. S., Maes, L., Coenye, T., Alex, A., Couch, R. D., Jones, T. A., Wouters, J., Mowbray, S. L. & Van Calenbergh, S., 9 Apr 2015, In : Journal of Medicinal Chemistry. 58, 7, p. 2988-3001 14 p.

Research output: Contribution to journalArticle

Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors

Thiry, A., Delayen, A., Goossens, L., Houssin, R., Ledecq, M., Frankart, A., Dogné, J-M., Wouters, J., Supuran, C. T., Hénichart, J-P. & Masereel, B., 1 Feb 2009, In : European Journal of Medicinal Chemistry. 44, 2, p. 511-8 8 p.

Research output: Contribution to journalArticle

Synthesis and catalytic evaluation of ruthenium-arene complexes bearing imidazol(in)ium-2-thiocarboxylate ligands

Hans, M., Willem, Q., Wouters, J., Demonceau, A. & Delaude, L., 28 Nov 2011, In : Organometallics. 30, 22, p. 6133-6142 10 p.

Research output: Contribution to journalArticle

Synthesis and catalytic evaluation of ruthenium-arene complexes generated using imidazol(in)ium-2-carboxylates and dithiocarboxylates

Delaude, L., Sauvage, X., Demonceau, A. & Wouters, J., 27 Jul 2009, In : Organometallics. 28, 14, p. 4056-4064 9 p.

Research output: Contribution to journalArticle

Synthesis and Crystallographic Characterization of a Maleimide Derivative of Tryptamine

Dubois, J., Colaço, M., Rondelet, G. & Wouters, J., 21 Nov 2016, In : Crystals. 6, 8 p.

Research output: Contribution to journalArticle

Open Access
File
15 Downloads (Pure)

Synthesis and organocatalytic applications of imidazol(in)ium-2- thiocarboxylates

Hans, M., Wouters, J., Demonceau, A. & Delaude, L., 1 Dec 2011, In : European Journal of Organic Chemistry. 35, p. 7083-7091 9 p.

Research output: Contribution to journalArticle

Synthesis of 16α-amino-pregnenolone derivatives via ionic liquid-catalyzed aza-Michael addition and their evaluation as C17,20-lyase inhibitors

Szánti-Pintér, E., Maksó, L., Gömöry, Á., Wouters, J., Edina Herman, B., Szécsi, M., Mikle, G., Kollár, L. & Skoda-Földes, R., 1 Jul 2017, In : Steroids. 123, p. 61-66 6 p.

Research output: Contribution to journalArticle

Synthesis of 2-Ureido-4-ferrocenyl Pyrimidine Guests. Investigation of Complementary Molecular Recognition of 2,6-Diaminopyridine

Fehér, C., Papp, M., Gömöry, Á., Nagy, L., Wouters, J., Lendvay, G. & Skoda-Földes, R., 2016, In : Organometallics. 35, 24, p. 4023-4032 10 p.

Research output: Contribution to journalArticle

2 Downloads (Pure)

Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase

Balti, M., Plas, A., Meinguet, C., Haufroid, M., Thémans, Q., Efrit, M. L., Wouters, J. & Lanners, S., 1 Aug 2017, In : Bioorganic and medicinal chemistry letters. 27, 15, p. 3607-3610 4 p.

Research output: Contribution to journalArticle

Synthesis of ferrocene-labelled 2-aminopyrimidine derivatives via homogeneous catalytic carbonylation

Fehér, C., Habuš, I., Wouters, J. & Skoda-Földes, R., 4 Sep 2014, In : Monatshefte fur Chemie. 145, 12, p. 1981-1986 6 p.

Research output: Contribution to journalArticle

23 Downloads (Pure)

Synthesis of novel 13α-18-norandrostane-ferrocene conjugates via homogeneous catalytic methods and their investigation on TRPV1 receptor activation

Szánti-Pintér, E., Wouters, J., Gömöry, Á., Sághy, É., Szoke, É., Helyes, Z., Kollár, L. & Skoda-Földes, R., 1 Dec 2015, In : Steroids. 104, p. 284-293 10 p.

Research output: Contribution to journalArticle

Synthesis of Tertiary Enamides by Ag2CO3-Promoted Pd-Catalyzed Alkenylation of Acyclic Secondary Amides

Delforge, A., Georgiou, I., Kremer, A., Wouters, J. & Bonifazi, D., 7 Oct 2016, In : Organic Letters. 18, 19, p. 4844-4847 4 p.

Research output: Contribution to journalArticle

Synthesis of two new alkyne-bearing linkers used for the preparation of siRNA for labeling by click chemistry with fluorine-18

Flagothier, J., Kaisin, G., Mercier, F., Thonon, D., Teller, N., Wouters, J. & Luxen, A., 1 Aug 2012, In : Applied Radiation and Isotopes. 70, 8, p. 1549-1557 9 p.

Research output: Contribution to journalArticle

Synthetic fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-d-xylulose 5-phosphate reductoisomerase or Plasmodium falciparum growth in vitro

Chofor, R., Risseeuw, M. D. P., Pouyez, J., Johny, C., Wouters, J., Dowd, C. S., Couch, R. D. & Van Calenbergh, S., 1 Feb 2014, In : Molecules. 19, 2, p. 2571-2587 17 p.

Research output: Contribution to journalArticle

Open Access

TAPSO at low temperature

Wouters, J. & Stalke, D., 15 Jul 1996, In : Acta crystallographica Section C: Crystal Structure communications. 52, 7, p. 1684-1686 3 p.

Research output: Contribution to journalArticle

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin

Sooriyaarachchi, S., Chofor, R., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Dowd, C. S., Maes, L., Wouters, J., Jones, T. A., Van Calenbergh, S. & Mowbray, S. L., 20 Sep 2016, In : ChemMedChem. p. 2024-2036 13 p.

Research output: Contribution to journalArticle

Targeting the serine pathway: a promising approach against tuberculosis?

Haufroid, M. & Wouters, J., 1 Jun 2019, In : Pharmaceuticals. 12, 2, 66.

Research output: Contribution to journalArticle

Open Access
File
23 Downloads (Pure)

Templated Chromophore Assembly on Peptide Scaffolds: A Structural Evolution

Rocard, L., Wragg, D., Jobbins, S. A., Luciani, L., Wouters, J., Leoni, S. & Bonifazi, D., 26 Oct 2018, In : Chemistry - A European Journal. 24, 60, p. 16136-16148 13 p.

Research output: Contribution to journalArticle

The crystal structure of sursassite from the Lienne Valley, Stavelot Massif, Belgium

Hatert, F., Fransolet, A. M., Wouters, J. & Bernhardt, H. J., 1 Sep 2008, In : European Journal of Mineralogy. 20, 5, p. 993-998 6 p.

Research output: Contribution to journalArticle

The dicyclo-hexyl-amine salt of RG108 (N-phthalyl-L-tryptophan), a potential epigenetic modulator

Braun, J., Boittiaux, I., Tilborg, A., Lambert, D. & Wouters, J., 2010, In : Acta Crystallographica. Section E. 66, Pt 12, p. o3175-6 66 p.

Research output: Contribution to journalArticle

File
19 Downloads (Pure)

The dipeptide pGlu-Pro-NH2

Wouters, J., Norberg, B. & Evrard, G., 15 Apr 1997, In : Acta crystallographica Section C: Crystal Structure communications. 53, 4, p. 477-480 4 p.

Research output: Contribution to journalArticle

The endoxylanases from family 11: Computer analysis of protein sequences reveals important structural and phylogenetic relationships

Sapag, A., Wouters, J., Lambert, C., De Ioannes, P., Eyzaguirre, J. & Depiereux, E., 9 Mar 2002, In : Journal of Biotechnology. 95, 2, p. 109-131 23 p.

Research output: Contribution to journalArticle

The molecular structure of caroxazone, a reversible monoamine oxidase inhibitor

Wouters, J., Evrard, G. & Durant, F., 1994, In : Acta crystallographica. Section C. 50, p. 1774-1777 4 p.

Research output: Contribution to journalArticle

The Use of Switchable Polarity Solvents for the Synthesis of 16‐Arylidene Steroids via Claisen–Schmidt Condensation

Ispán, D., Szánti-Pintér, E., Papp, M., Wouters, J., Tumanov, N., Balázs Zsirka, B., Gömöry, Á., Kollár, L. & Skoda-Földes, R., 29 Jun 2018, In : European Journal of Organic Chemistry. 2018, 24, p. 3236-3244 9 p.

Research output: Contribution to journalArticle

Open Access