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Research Output

2017

Synthesis of 16α-amino-pregnenolone derivatives via ionic liquid-catalyzed aza-Michael addition and their evaluation as C17,20-lyase inhibitors

Szánti-Pintér, E., Maksó, L., Gömöry, Á., Wouters, J., Edina Herman, B., Szécsi, M., Mikle, G., Kollár, L. & Skoda-Földes, R., 1 Jul 2017, In : Steroids. 123, p. 61-66 6 p.

Research output: Contribution to journalArticle

Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase

Balti, M., Plas, A., Meinguet, C., Haufroid, M., Thémans, Q., Efrit, M. L., Wouters, J. & Lanners, S., 1 Aug 2017, In : Bioorganic and medicinal chemistry letters. 27, 15, p. 3607-3610 4 p.

Research output: Contribution to journalArticle

Toward Fractioning of Isomers through Binding-Induced Acceleration of Azobenzene Switching

Vulcano, R., Pengo, P., Velari, S., Wouters, J., De Vita, A., Tecilla, P. & Bonifazi, D., 20 Dec 2017, In : Journal of the American Chemical Society. 139, 50, p. 18271-18280 10 p.

Research output: Contribution to journalArticle

Versatile Self-Adapting Boronic Acids for H-Bond Recognition: From Discrete to Polymeric Supramolecules

Georgiou, I., Kervyn De Meerendre, S., Rossignon, A., De Leo, F., Wouters, J., Bruylants, G. & Bonifazi, D., 22 Feb 2017, In : Journal of the American Chemical Society. 139, 7, p. 2710-2727 18 p.

Research output: Contribution to journalArticle

2016

A nano-sized container for specific encapsulation of isolated water molecules

Lavendomme, R., Marcélis, L., Wouters, J., Luhmer, M. & Jabin, I., 1 Jan 2016, In : Chemical Communications. 52, 98, p. 14109-14112 4 p.

Research output: Contribution to journalArticle

A selective calix[6]arene-based fluorescent chemosensor for phosphatidylcholine type lipids

Brunetti, E., Moerkerke, S., Wouters, J., Bartik, K. & Jabin, I., 2016, In : Organic and Biomolecular Chemistry. 14, 43, p. 10201-10207 7 p.

Research output: Contribution to journalArticle

L’expérience d’une collaboration fructueuse et pérenne entre la Belgique et la Tunisie dans le district minier de Nefza-Sejnane

Yans, J., Ben Abdallah, R., Decree, S., Chargui, H., Dekoninck, A., Moussi, B., Dupuis, C., Chaftar, H-R., Vandeneede, V., Hajjaji, W., Pilate, P., HATIRA, N., Baele, J. M., Wouters, J. & Jamoussi, F., 7 Apr 2016, Ressources and Innovative Geology 2016 - Abstract book.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Peculiar Case of Levetiracetam and Etiracetam α-Ketoglutaric Acid Cocrystals: Obtaining a Stable Conglomerate of Etiracetam

George, F., Norberg, B., Robeyns, K., Wouters, J. & Leyssens, T., 7 Sep 2016, In : Crystal Growth and Design. 16, 9, p. 5273-5282 10 p.

Research output: Contribution to journalArticle

Reinvestigation of the Branimycin Stereochemistry at Position 17-C

Čikoš, A., Triballeau, N., Hubbard, P. A., Žiher, D., Stouten, P. F. W., Doyon, J. G. P. O., Deschrijver, T., Wouters, J., Lépine, R. H. M. & Saniere, L., 19 Feb 2016, In : Organic Letters. 18, 4, p. 780-783 4 p.

Research output: Contribution to journalArticle

Open Access
File
34 Downloads (Pure)

Supramolecular Wiring of Benzo-1,3-chalcogenazoles through Programmed Chalcogen Bonding Interactions

Kremer, A., Fermi, A., Biot, N., Wouters, J. & Bonifazi, D., 11 Apr 2016, In : Chemistry (Weinheim an der Bergstrasse, Germany). 22, 16, p. 5665-5675 11 p.

Research output: Contribution to journalArticle

Synthesis and Crystallographic Characterization of a Maleimide Derivative of Tryptamine

Dubois, J., Colaço, M., Rondelet, G. & Wouters, J., 21 Nov 2016, In : Crystals. 6, 8 p.

Research output: Contribution to journalArticle

Open Access
File
11 Downloads (Pure)

Synthesis of 2-Ureido-4-ferrocenyl Pyrimidine Guests. Investigation of Complementary Molecular Recognition of 2,6-Diaminopyridine

Fehér, C., Papp, M., Gömöry, Á., Nagy, L., Wouters, J., Lendvay, G. & Skoda-Földes, R., 2016, In : Organometallics. 35, 24, p. 4023-4032 10 p.

Research output: Contribution to journalArticle

2 Downloads (Pure)

Synthesis of Tertiary Enamides by Ag2CO3-Promoted Pd-Catalyzed Alkenylation of Acyclic Secondary Amides

Delforge, A., Georgiou, I., Kremer, A., Wouters, J. & Bonifazi, D., 7 Oct 2016, In : Organic Letters. 18, 19, p. 4844-4847 4 p.

Research output: Contribution to journalArticle

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin

Sooriyaarachchi, S., Chofor, R., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Dowd, C. S., Maes, L., Wouters, J., Jones, T. A., Van Calenbergh, S. & Mowbray, S. L., 20 Sep 2016, In : ChemMedChem. p. 2024-2036 13 p.

Research output: Contribution to journalArticle

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties

Meinguet, C., Bruyère, C., Frédérick, R., Mathieu, V., Vancraeynest, C., Pochet, L., Laloy, J., Mortier, J., Wolber, G., Kiss, R., Masereel, B. & Wouters, J., 13 Apr 2015, In : European Journal of Medicinal Chemistry. 94, p. 45-55 11 p., 7726.

Research output: Contribution to journalArticle

Open Access

A biomimetic heteroditopic receptor for zwitterions in protic media

Cornut, D., Moerkerke, S., Wouters, J., Bruylants, G. & Jabin, I., 2015, In : Chemistry - An Asian Journal. 10, 2, p. 440-446 7 p.

Research output: Contribution to journalArticle

Concentré de CHIMIE

Wouters, J., 2015, Presses universitaires de Namur. 404 p.

Research output: Book/Report/JournalBook

4 Downloads (Pure)

Mechanochemical synthesis of phthalimides with crystal structures of intermediates and products

Colaco, M. O., Dubois, J. & Wouters, J., 28 Mar 2015, In : CrystEngComm. 17, 12, p. 2523-2528 6 p.

Research output: Contribution to journalArticle

Probing the Diastereoselectivity of Staudinger Reactions Catalyzed by N-Heterocyclic Carbenes

Hans, M., Wouters, J., Demonceau, A. & Delaude, L., 1 Jul 2015, In : Chemistry: A European Journal. 21, 30, p. 10870-10877 8 p.

Research output: Contribution to journalArticle

Selective Recognition of Phosphatidylcholine Lipids by a Biomimetic Calix[6]tube Receptor

Moerkerke, S., Wouters, J. & Jabin, I., 10 Aug 2015, In : Journal of Organic Chemistry. 80, 17, p. 8720-8726 7 p.

Research output: Contribution to journalArticle

Solid-state investigation on a new dimorphic substituted N-salicylidene compound: Insights into its thermochromic behaviour

Carletta, A., Dubois, J., Tilborg, A. & Wouters, J., 14 May 2015, In : CrystEngComm. 17, 18, p. 3509-3518 10 p.

Research output: Contribution to journalArticle

20 Downloads (Pure)

Stereoselective synthesis of boat-locked glycosides designed as glycosyl hydrolase conformational probes

Thiery, E., Reniers, J., Wouters, J. & Vincent, S. P., 2015, In : European Journal of Organic Chemistry. 2015, 7, p. 1472-1484 13 p.

Research output: Contribution to journalArticle

2 Downloads (Pure)

Structural Investigation of Substituent Effect on Hydrogen Bonding in (S)-Phenylglycine Amide Benzaldimines

George, F., Norberg, B., Wouters, J. & Leyssens, T., 5 Aug 2015, In : Crystal Growth and Design. 15, 8, p. 4005-4019 15 p.

Research output: Contribution to journalArticle

Supramolecular Assistance for the Selective Demethylation of Calixarene-Based Receptors

Danjou, P. E., De Leener, G., Cornut, D., Moerkerke, S., Mameri, S., Lascaux, A., Wouters, J., Brugnara, A., Colasson, B., Reinaud, O. & Jabin, I., 15 May 2015, In : Journal of Organic Chemistry. 80, 10, p. 5084-5091 8 p.

Research output: Contribution to journalArticle

Synthesis and Bioactivity of β-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase

Chofor, R., Sooriyaarachchi, S., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C. S., Maes, L., Coenye, T., Alex, A., Couch, R. D., Jones, T. A., Wouters, J., Mowbray, S. L. & Van Calenbergh, S., 9 Apr 2015, In : Journal of Medicinal Chemistry. 58, 7, p. 2988-3001 14 p.

Research output: Contribution to journalArticle

Synthesis of novel 13α-18-norandrostane-ferrocene conjugates via homogeneous catalytic methods and their investigation on TRPV1 receptor activation

Szánti-Pintér, E., Wouters, J., Gömöry, Á., Sághy, É., Szoke, É., Helyes, Z., Kollár, L. & Skoda-Földes, R., 1 Dec 2015, In : Steroids. 104, p. 284-293 10 p.

Research output: Contribution to journalArticle

2014

2,5-Diamide-substituted five-membered heterocycles: Challenging molecular synthons

Fabbro, C., Armani, S., Carloni, L. E., De Leo, F., Wouters, J. & Bonifazi, D., 2014, In : European Journal of Organic Chemistry. 2014, 25, p. 5487–5500 14 p.

Research output: Contribution to journalArticle

Bis-(1,2,3,4-tetrahydroisoquinolinium): A Chiral Scaffold for Developing High-Affinity Ligands for SK Channels

Liégeois, J. F., Wouters, J., Seutin, V. & Dilly, S., Apr 2014, In : ChemMedChem.

Research output: Contribution to journalArticle

Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration

Badarau, E., Dilly, S., Wouters, J., Seutin, V. & Liégeois, J. F., 15 Dec 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, 24, p. 5616-5620 5 p.

Research output: Contribution to journalArticle

1 Downloads (Pure)

Cocrystal formation between chiral compounds: How cocrystals differ from salts

Springuel, G., Robeyns, K., Norberg, B., Wouters, J. & Leyssens, T., 6 Aug 2014, In : Crystal Growth and Design. 14, 8, p. 3996-4004 9 p.

Research output: Contribution to journalArticle

Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: Dimethylallyl diphosphate isomerase from streptococcus pneumoniae

De Ruyck, J., Janczak, M. W., Neti, S. S., Rothman, S. C., Schubert, H. L., Cornish, R. M., Matagne, A., Wouters, J. & Poulter, C. D., 7 Jul 2014, In : ChemBioChem. 15, 10, p. 1452-8 7 p.

Research output: Contribution to journalArticle

Does chirality influence the tendency toward cocrystal formation?

George, F., Tumanov, N., Norberg, B., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 4 Jun 2014, In : Crystal Growth and Design. 14, 6, p. 2880-2892 13 p.

Research output: Contribution to journalArticle

How cocrystallization affects solid-state tautomerism : Stanozolol case study

Tilborg, A., Springuel, G., Norberg, B., Wouters, J. & Leyssens, T., 2 Jul 2014, In : Crystal Growth and Design. 14, 7, p. 3408-3422 15 p.

Research output: Contribution to journalArticle

Ionic co-crystals of racetams: Solid-state properties enhancement of neutral active pharmaceutical ingredients via addition of Mg2+ and Ca2+ chlorides

Grepioni, F., Wouters, J., Braga, D., Nanna, S., Fours, B., Coquerel, G., Longfils, G., Rome, S., Aerts, L. & Quéré, L., 14 Jul 2014, In : CrystEngComm. 16, 26, p. 5887-5896 10 p.

Research output: Contribution to journalArticle

Mechanosynthesis, a method of choice in solid state synthesis

Dubois, J., Colaco, M. O. & Wouters, J., Dec 2014, In : Chimie nouvelle. 117, p. 21-30 10 p.

Research output: Contribution to journalArticle

52 Downloads (Pure)

Palladium-nanoparticle-catalyzed 1,7-palladium migration involving C-H activation, followed by intramolecular lamination: Regioselective synthesis of N 1-arylbenzotriazoles and an evaluation of their inhibitory activity toward indoleamine 2,3-dioxygenase

Takagi, K., Al-Amin, M., Hoshiya, N., Wouters, J., Sugimoto, H., Shiro, Y., Fukuda, H., Shuto, S. & Arisawa, M., 3 Jul 2014, In : Journal of Organic Chemistry. 79, 13, p. 6366-6371 6 p.

Research output: Contribution to journalArticle

Open Access
30 Downloads (Pure)

Structural analysis of some bis-(8-isopropyl-isoquinolinium) derivatives reveals a preferential folded conformation leading to a stereoselective attack by sodium borohydride

Dilly, S., Badarau, E., Dufour, F., Nistor, I., Hubert, P., Seutin, V., Wouters, J. & Liégeois, J. F., 25 Sep 2014, In : Journal of molecular structure. 1074, p. 435-440 6 p.

Research output: Contribution to journalArticle

Structural insight into cocrystallization with zwitterionic co-formers: Cocrystals of S-naproxen

Tumanova, N., Tumanov, N., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 21 Sep 2014, In : CrystEngComm. 16, 35, p. 8185-8196 12 p.

Research output: Contribution to journalArticle

Synthesis of ferrocene-labelled 2-aminopyrimidine derivatives via homogeneous catalytic carbonylation

Fehér, C., Habuš, I., Wouters, J. & Skoda-Földes, R., 4 Sep 2014, In : Monatshefte fur Chemie. 145, 12, p. 1981-1986 6 p.

Research output: Contribution to journalArticle

23 Downloads (Pure)