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Research Output 1992 2020

2017

Toward Fractioning of Isomers through Binding-Induced Acceleration of Azobenzene Switching

Vulcano, R., Pengo, P., Velari, S., Wouters, J., De Vita, A., Tecilla, P. & Bonifazi, D., 20 Dec 2017, In : Journal of the American Chemical Society. 139, 50, p. 18271-18280 10 p.

Research output: Contribution to journalArticle

Azobenzene
Isomerization
Isomers
Hot Temperature
Uracil
Boronic Acids
Acids
Bearings (structural)
Supramolecular chemistry
Crystal engineering
2016

A nano-sized container for specific encapsulation of isolated water molecules

Lavendomme, R., Marcélis, L., Wouters, J., Luhmer, M. & Jabin, I., 1 Jan 2016, In : Chemical Communications. 52, 98, p. 14109-14112 4 p.

Research output: Contribution to journalArticle

Encapsulation
Containers
Molecules
Water
Nuclear magnetic resonance

A selective calix[6]arene-based fluorescent chemosensor for phosphatidylcholine type lipids

Brunetti, E., Moerkerke, S., Wouters, J., Bartik, K. & Jabin, I., 2016, In : Organic and Biomolecular Chemistry. 14, 43, p. 10201-10207 7 p.

Research output: Contribution to journalArticle

Phosphatidylcholines
lipids
Lipids
Phosphatidylethanolamines
Phospholipid Transfer Proteins
Conformations
tautomers
Thiones
crystal structure
Crystal structure

L’expérience d’une collaboration fructueuse et pérenne entre la Belgique et la Tunisie dans le district minier de Nefza-Sejnane

Yans, J., Ben Abdallah, R., Decree, S., Chargui, H., Dekoninck, A., Moussi, B., Dupuis, C., Chaftar, H-R., Vandeneede, V., Hajjaji, W., Pilate, P., HATIRA, N., Baele, J. M., Wouters, J. & Jamoussi, F., 7 Apr 2016, Ressources and Innovative Geology 2016 - Abstract book.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Peculiar Case of Levetiracetam and Etiracetam α-Ketoglutaric Acid Cocrystals: Obtaining a Stable Conglomerate of Etiracetam

George, F., Norberg, B., Robeyns, K., Wouters, J. & Leyssens, T., 7 Sep 2016, In : Crystal Growth and Design. 16, 9, p. 5273-5282 10 p.

Research output: Contribution to journalArticle

etiracetam
Ketoglutaric Acids
Enantiomers
enantiomers
tautomers
Dicarboxylic Acids
dicarboxylic acids
Tuning
tuning
solid state

Reinvestigation of the Branimycin Stereochemistry at Position 17-C

Čikoš, A., Triballeau, N., Hubbard, P. A., Žiher, D., Stouten, P. F. W., Doyon, J. G. P. O., Deschrijver, T., Wouters, J., Lépine, R. H. M. & Saniere, L., 19 Feb 2016, In : Organic Letters. 18, 4, p. 780-783 4 p.

Research output: Contribution to journalArticle

Stereochemistry
stereochemistry
Molecular modeling
X ray crystallography
X Ray Crystallography
31 Downloads (Pure)
Open Access
File
Nucleosomes
DNA Methylation
Histones
Epigenomics
Histone Code

Supramolecular Wiring of Benzo-1,3-chalcogenazoles through Programmed Chalcogen Bonding Interactions

Kremer, A., Fermi, A., Biot, N., Wouters, J. & Bonifazi, D., 11 Apr 2016, In : Chemistry (Weinheim an der Bergstrasse, Germany). 22, 16, p. 5665-5675 11 p.

Research output: Contribution to journalArticle

Chalcogens
Electric wiring
Nitrogen
Cyclization
Surface potential
Factor XIIa
Coumarins
Structure-Activity Relationship
Enzyme Precursors
Blood Coagulation
10 Downloads (Pure)

Synthesis and Crystallographic Characterization of a Maleimide Derivative of Tryptamine

Dubois, J., Colaço, M., Rondelet, G. & Wouters, J., 21 Nov 2016, In : Crystals. 6, 8 p.

Research output: Contribution to journalArticle

Open Access
File
tryptamines
Maleic Anhydrides
Pyrroles
Crystallography
Maleic anhydride
2 Downloads (Pure)

Synthesis of 2-Ureido-4-ferrocenyl Pyrimidine Guests. Investigation of Complementary Molecular Recognition of 2,6-Diaminopyridine

Fehér, C., Papp, M., Gömöry, Á., Nagy, L., Wouters, J., Lendvay, G. & Skoda-Földes, R., 2016, In : Organometallics. 35, 24, p. 4023-4032 10 p.

Research output: Contribution to journalArticle

Molecular recognition
pyrimidines
Hydrogen bonds
hydrogen bonds
nuclear magnetic resonance
Alkenylation
Acrylates
Amides
amides
Metals

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin

Sooriyaarachchi, S., Chofor, R., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Dowd, C. S., Maes, L., Wouters, J., Jones, T. A., Van Calenbergh, S. & Mowbray, S. L., 20 Sep 2016, In : ChemMedChem. p. 2024-2036 13 p.

Research output: Contribution to journalArticle

Plasmodium falciparum
Polyisoprenyl Phosphates
Enzymes
Plasmodium
Biosynthesis
Open Access
Harmine
Quantitative Structure-Activity Relationship
Solubility
Derivatives
Cells

A biomimetic heteroditopic receptor for zwitterions in protic media

Cornut, D., Moerkerke, S., Wouters, J., Bruylants, G. & Jabin, I., 2015, In : Chemistry - An Asian Journal. 10, 2, p. 440-446 7 p.

Research output: Contribution to journalArticle

Betaine
Biomimetics
Liquids
Anserine
Thiourea

Concentré de CHIMIE

Wouters, J., 2015, Presses universitaires de Namur. 404 p.

Research output: Book/Report/JournalBook

4 Downloads (Pure)
Heme Oxygenase-1
Molecular modeling
imidazoles
inhibitors
Conformations

Mechanochemical synthesis of phthalimides with crystal structures of intermediates and products

Colaco, M. O., Dubois, J. & Wouters, J., 28 Mar 2015, In : CrystEngComm. 17, 12, p. 2523-2528 6 p.

Research output: Contribution to journalArticle

Phthalimides
phthalimides
Crystal structure
solid state
crystal structure
Harmine
Cyclodextrins
Solubility
Pharmaceutical Preparations
Protons

Probing the Diastereoselectivity of Staudinger Reactions Catalyzed by N-Heterocyclic Carbenes

Hans, M., Wouters, J., Demonceau, A. & Delaude, L., 1 Jul 2015, In : Chemistry: A European Journal. 21, 30, p. 10870-10877 8 p.

Research output: Contribution to journalArticle

Imines
Cycloaddition
Molecular structure
X ray crystallography
Thermogravimetric analysis

Selective Recognition of Phosphatidylcholine Lipids by a Biomimetic Calix[6]tube Receptor

Moerkerke, S., Wouters, J. & Jabin, I., 10 Aug 2015, In : Journal of Organic Chemistry. 80, 17, p. 8720-8726 7 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamines
Phosphorylcholine
Biomimetics
Phosphatidylcholines
Lipids
Lead compounds
lead compounds
Thiones
polymorphism
Polymorphism
20 Downloads (Pure)
Aniline
aniline
solid state
X ray analysis
Liquid nitrogen
glucosides
boats
Boats
Hydrolases
Glycosides
2 Downloads (Pure)
Trimethoprim
Salts
salts
solid state
application programming interface

Structural Investigation of Substituent Effect on Hydrogen Bonding in (S)-Phenylglycine Amide Benzaldimines

George, F., Norberg, B., Wouters, J. & Leyssens, T., 5 Aug 2015, In : Crystal Growth and Design. 15, 8, p. 4005-4019 15 p.

Research output: Contribution to journalArticle

Amides
amides
Hydrogen bonds
hydrogen
Halogens

Supramolecular Assistance for the Selective Demethylation of Calixarene-Based Receptors

Danjou, P. E., De Leener, G., Cornut, D., Moerkerke, S., Mameri, S., Lascaux, A., Wouters, J., Brugnara, A., Colasson, B., Reinaud, O. & Jabin, I., 15 May 2015, In : Journal of Organic Chemistry. 80, 10, p. 5084-5091 8 p.

Research output: Contribution to journalArticle

Calixarenes
Conformations
Molecules

Synthesis and Bioactivity of β-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase

Chofor, R., Sooriyaarachchi, S., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C. S., Maes, L., Coenye, T., Alex, A., Couch, R. D., Jones, T. A., Wouters, J., Mowbray, S. L. & Van Calenbergh, S., 9 Apr 2015, In : Journal of Medicinal Chemistry. 58, 7, p. 2988-3001 14 p.

Research output: Contribution to journalArticle

Polyisoprenyl Phosphates
Mycobacterium smegmatis
Plasmodium
Enzymes
Plasmodium falciparum

Synthesis of novel 13α-18-norandrostane-ferrocene conjugates via homogeneous catalytic methods and their investigation on TRPV1 receptor activation

Szánti-Pintér, E., Wouters, J., Gömöry, Á., Sághy, É., Szoke, É., Helyes, Z., Kollár, L. & Skoda-Földes, R., 1 Dec 2015, In : Steroids. 104, p. 284-293 10 p.

Research output: Contribution to journalArticle

Norandrostanes
Chemical activation
Steroids
Derivatives
Alkynes
2014
Diamide
Thiophenes
thiophenes
Conformations
Atoms

Bis-(1,2,3,4-tetrahydroisoquinolinium): A Chiral Scaffold for Developing High-Affinity Ligands for SK Channels

Liégeois, J. F., Wouters, J., Seutin, V. & Dilly, S., Apr 2014, In : ChemMedChem.

Research output: Contribution to journalArticle

tetrandrine
Scaffolds
Isomers
Small-Conductance Calcium-Activated Potassium Channels
Tetrahydroisoquinolines
1 Downloads (Pure)

Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration

Badarau, E., Dilly, S., Wouters, J., Seutin, V. & Liégeois, J. F., 15 Dec 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, 24, p. 5616-5620 5 p.

Research output: Contribution to journalArticle

Chemical modification
Scaffolds
Derivatives
Stereoisomerism
Enantiomers

Cocrystal formation between chiral compounds: How cocrystals differ from salts

Springuel, G., Robeyns, K., Norberg, B., Wouters, J. & Leyssens, T., 6 Aug 2014, In : Crystal Growth and Design. 14, 8, p. 3996-4004 9 p.

Research output: Contribution to journalArticle

Coulomb interactions
Hydrogen bonds
Screening
screening
Salts

Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: Dimethylallyl diphosphate isomerase from streptococcus pneumoniae

De Ruyck, J., Janczak, M. W., Neti, S. S., Rothman, S. C., Schubert, H. L., Cornish, R. M., Matagne, A., Wouters, J. & Poulter, C. D., 7 Jul 2014, In : ChemBioChem. 15, 10, p. 1452-8 7 p.

Research output: Contribution to journalArticle

Isomerases
Streptococcus pneumoniae
Crystal structure
Kinetics
Terpenes

Does chirality influence the tendency toward cocrystal formation?

George, F., Tumanov, N., Norberg, B., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 4 Jun 2014, In : Crystal Growth and Design. 14, 6, p. 2880-2892 13 p.

Research output: Contribution to journalArticle

etiracetam
Chirality
chirality
Hydrogen bonds
tendencies

How cocrystallization affects solid-state tautomerism : Stanozolol case study

Tilborg, A., Springuel, G., Norberg, B., Wouters, J. & Leyssens, T., 2 Jul 2014, In : Crystal Growth and Design. 14, 7, p. 3408-3422 15 p.

Research output: Contribution to journalArticle

Stanozolol
Freezing
X ray powder diffraction
Crystal structure
Single crystals

Ionic co-crystals of racetams: Solid-state properties enhancement of neutral active pharmaceutical ingredients via addition of Mg2+ and Ca2+ chlorides

Grepioni, F., Wouters, J., Braga, D., Nanna, S., Fours, B., Coquerel, G., Longfils, G., Rome, S., Aerts, L. & Quéré, L., 14 Jul 2014, In : CrystEngComm. 16, 26, p. 5887-5896 10 p.

Research output: Contribution to journalArticle

ingredients
Drug products
Chlorides
drugs
chlorides
52 Downloads (Pure)

Mechanosynthesis, a method of choice in solid state synthesis

Dubois, J., Colaco, M. O. & Wouters, J., Dec 2014, In : Chimie nouvelle. 117, p. 21-30 10 p.

Research output: Contribution to journalArticle

Palladium-nanoparticle-catalyzed 1,7-palladium migration involving C-H activation, followed by intramolecular lamination: Regioselective synthesis of N 1-arylbenzotriazoles and an evaluation of their inhibitory activity toward indoleamine 2,3-dioxygenase

Takagi, K., Al-Amin, M., Hoshiya, N., Wouters, J., Sugimoto, H., Shiro, Y., Fukuda, H., Shuto, S. & Arisawa, M., 3 Jul 2014, In : Journal of Organic Chemistry. 79, 13, p. 6366-6371 6 p.

Research output: Contribution to journalArticle

Open Access
Indoleamine-Pyrrole 2,3,-Dioxygenase
Palladium
Nanoparticles
Bearings (structural)
Chemical activation
30 Downloads (Pure)
Salts
Amino Acids
Pharmaceutical Preparations
Ajmaline
Cephalexin

Structural analysis of some bis-(8-isopropyl-isoquinolinium) derivatives reveals a preferential folded conformation leading to a stereoselective attack by sodium borohydride

Dilly, S., Badarau, E., Dufour, F., Nistor, I., Hubert, P., Seutin, V., Wouters, J. & Liégeois, J. F., 25 Sep 2014, In : Journal of molecular structure. 1074, p. 435-440 6 p.

Research output: Contribution to journalArticle

Structural analysis
Conformations
Derivatives
Stereoselectivity
Stereoisomerism

Structural insight into cocrystallization with zwitterionic co-formers: Cocrystals of S-naproxen

Tumanova, N., Tumanov, N., Robeyns, K., Filinchuk, Y., Wouters, J. & Leyssens, T., 21 Sep 2014, In : CrystEngComm. 16, 35, p. 8185-8196 12 p.

Research output: Contribution to journalArticle

Naproxen
amino acids
Amino acids
alanine
Amino Acids
23 Downloads (Pure)

Synthesis of ferrocene-labelled 2-aminopyrimidine derivatives via homogeneous catalytic carbonylation

Fehér, C., Habuš, I., Wouters, J. & Skoda-Földes, R., 4 Sep 2014, In : Monatshefte fur Chemie. 145, 12, p. 1981-1986 6 p.

Research output: Contribution to journalArticle

Carbonylation
Nucleophiles
Derivatives
X ray crystallography
Palladium

Synthetic fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-d-xylulose 5-phosphate reductoisomerase or Plasmodium falciparum growth in vitro

Chofor, R., Risseeuw, M. D. P., Pouyez, J., Johny, C., Wouters, J., Dowd, C. S., Couch, R. D. & Van Calenbergh, S., 1 Feb 2014, In : Molecules. 19, 2, p. 2571-2587 17 p.

Research output: Contribution to journalArticle

Open Access
Plasmodium falciparum
Chelation
enzymes
phosphates
analogs
Indoleamine-Pyrrole 2,3,-Dioxygenase
Derivatives
Scaffolds
Substitution reactions
Immunotherapy

Thiosemicarbazide Derivatives as Novel Indolamine-2,3-dioxygenase (IDO) Inhibitors

Serra, S., Moineaux, L., Vancraeynest, C., Masereel, B., Pochet, L., Wouters, J. & Frédérick, R., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 280

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution