Johan Wouters — the Research Portal

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Education/Academic qualification

Doctor of Science, University of Namur

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Projects 1990 2022

1 Not started
15 Active
58 Finished

Structural approach of M.tuberculosis phosphoserine phosphatase as drug target for the design of original inhibitors

Pierson, E. & Wouters, J.

1/10/18 → 30/09/19

Project: Research › Research, Dissertation project

Development of inhibitors of LDHB tetramerizatuion to block oxidative lactate metabolism and signaling in cancer

Sonveaux, P., Frédérick, R., Wouters, J. & Piel, G.

1/10/18 → 30/09/20

Project: Research

Cryo- and photo-crystallography of thermo- and photochromism in the solidstate: Photo/Thermo-CoXal approach

Carletta, A. & Wouters, J.

1/10/18 → 30/09/20

Project: Research › Research, Dissertation project

Structural study of membrane proteins involved in chemoresistance of cancer cells

Dal Maso, T. & Wouters, J.

1/01/18 → 30/09/19

Project: Research › Dissertation project, Research

Cocrystals as an alternative to combination drugs: cocrystallization, physico-chemical characterization and structural determination of cocrystallized active pharmaceutical ingredients

Bodart, L. & Wouters, J.

1/10/17 → 26/09/19

Project: Research › Dissertation project, Research

Research Output 1992 2018

4864 Citations
36 h-Index
275 Article
19 Poster
12 Conference contribution
10 Literature review
16 More

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting D-alanine-D-alanine ligase in bacterio

Ameryckx, A., Thabault, L., Pochet, L., Leimanis, S., Poupaert, J., Wouters, J., Joris, B., Van Bambeke, F. & Frederick, R., 5 Nov 2018, In : European journal of medicinal chemistry / Chimica therapeutica. 159, 5, p. 324-338 15 p.

Research output: Contribution to journal › Article

Open Access

Anti-Infective Agents

Cytotoxicity

Cells

Peptidoglycan

Structure-Activity Relationship

Acidochromic spiropyran-merocyanine stabilisation in the solid state

Seiler, V. K., Callebaut, K., Robeyns, K., Tumanov, N., Wouters, J., Champagne, B. & Leyssens, T., 1 Jan 2018, In : CrystEngComm. 20, 24, p. 3318-3327 10 p.

Research output: Contribution to journal › Article

Inorganic acids

Stabilization

stabilization

solid state

acids

A Possible Infinite Number of Components in a Single Crystalline Phase: On the Isomorphism of Brivaracetam-Guest Molecules

Couvrat, N., Sanselme, M., Cartigny, Y., De Smet, F., Rome, S., Aerts, L., Quéré, L., Wouters, J. & Coquerel, G., 5 Sep 2018, In : Crystal Growth and Design. 18, 9, p. 4807-4810 4 p.

Research output: Contribution to journal › Article

isomorphism

Alkanes

Paraffins

alkanes

epilepsy

Direct Access by Mechanochemistry or Sonochemistry to Protonated Merocyanines: Components of a Four‐State Molecular Switch

Colaço, M., Carletta, A., Van Gysel, M., Robeyns, K., Tumanov, N. & Wouters, J., 2 Jul 2018, In : ChemistryOPEN. 7, 7, p. 520-526 7 p.

Research output: Contribution to journal › Article

Open Access

File

Sonochemistry

Switches

Condensation reactions

X ray crystallography

Iodides

Effects of Empirical Dispersion Energy on the Geometrical Parameters and Relative Energy of a Salicylideneaniline Molecular Switch in the Solid State

Quertinmont, J., Leyssens, T., Wouters, J. & Champagne, B., 8 Mar 2018, In : Crystals. 8, 3, p. 1 - 8 8 p., 125.

Research output: Contribution to journal › Article

Open Access

File

Density functional theory

switches

Switches

density functional theory

solid state

Datasets

CCDC 979360: Experimental Crystal Structure Determination

Badarau, E. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2014

DOI: 10.5517/cc11w389, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc11w389&sid=DataCite

Dataset

CCDC 999300: Experimental Crystal Structure Determination

Al-Amin, M. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2014

DOI: 10.5517/cc12jvhy, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc12jvhy&sid=DataCite

Dataset

CCDC 282947: Experimental Crystal Structure Determination

Aschenbach, L. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2007

DOI: 10.5517/cc9hfbj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc9hfbj&sid=DataCite

Dataset

CCDC 910796: Experimental Crystal Structure Determination

Reniers, J. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2015

DOI: 10.5517/cczkrjs, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cczkrjs&sid=DataCite

Dataset

CCDC 685601: Experimental Crystal Structure Determination

Borremans, F. A. M. (Contributor), Cambridge Crystallographic Data Centre, 1 Jan 2010

DOI: 10.5517/ccr0f5b, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccr0f5b&sid=DataCite

Dataset

Thesis

Analyse et modélisation de nouveaux inhibiteurs non nucléosidiques de la transcriptase inverse du virus de l'immunodéficience humaine de type 1 (VIH-1)

Author: Boland, S., 27 Feb 2004

Supervisor: Durant, F. (Supervisor), Andre, J. (Jury), Hevesi, L. (Jury), Wouters, J. (Jury) & Burny, A. (External person) (Jury)

Student thesis: Doc types › Doctor of Sciences

File

Analyse structurale et électronique au moyen de méthodes physico-chimiques expérimentales et théoriques de l'interaction entre le récepteur du thromboxane et ses antagonistes

Author: Michaux, C., 1999

Supervisor: Durant, F. (Supervisor), Masereel, B. (Co-Supervisor) & Wouters, J. (Co-Supervisor)

Student thesis: Master types › Master in Chemistry

Approche structurale de l'inhibition de la Fatty acid amide hydrolase humaine

Author: Wespes, C., 2005

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master types › Master in Chemistry

Caractérisation enzymatique et structurale d'inhibiteurs indoliques de la tryptophane 2,3-dioxygénase.: Mémoire présenté pour l'obtention du grade académique de Master en Chimie "Chimie du Vivant et des Nanomatériaux" : Finalité Spécialisée.

Author: Molle, N., 2012

Supervisor: Wouters, J. (Supervisor), Dolusic, E. (Jury), Moineaux, L. (Jury), Fonder, G. (Jury) & Leherte, L. (Jury)

Student thesis: Master types › Master in Chemistry

Caractérisation structurale de la 5-lipoxygénase humaine et de son inhibition: support à la conception rationnelle d'inhibiteurs mixtes 5-LOX-COX-2

Author: Charlier, C., 15 Feb 2006

Supervisor: Wouters, J. (Supervisor), Durant, F. (Co-Supervisor), Dogne, J. (Jury), Vercauteren, D. (Jury), Hennichart, J. (External person) (Jury) & Moureau, F. (External person) (Jury)

Student thesis: Doc types › Doctor of Sciences

File