• 200 Citations
  • 8 h-Index
20082016

Research output per year

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Research Output

  • 200 Citations
  • 8 h-Index
  • 10 Article
  • 1 Poster
2016

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin

Sooriyaarachchi, S., Chofor, R., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Dowd, C. S., Maes, L., Wouters, J., Jones, T. A., Van Calenbergh, S. & Mowbray, S. L., 20 Sep 2016, In : ChemMedChem. p. 2024-2036 13 p.

Research output: Contribution to journalArticle

2015

Synthesis and Bioactivity of β-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase

Chofor, R., Sooriyaarachchi, S., Risseeuw, M. D. P., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C. S., Maes, L., Coenye, T., Alex, A., Couch, R. D., Jones, T. A., Wouters, J., Mowbray, S. L. & Van Calenbergh, S., 9 Apr 2015, In : Journal of Medicinal Chemistry. 58, 7, p. 2988-3001 14 p.

Research output: Contribution to journalArticle

2014

Synthetic fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-d-xylulose 5-phosphate reductoisomerase or Plasmodium falciparum growth in vitro

Chofor, R., Risseeuw, M. D. P., Pouyez, J., Johny, C., Wouters, J., Dowd, C. S., Couch, R. D. & Van Calenbergh, S., 1 Feb 2014, In : Molecules. 19, 2, p. 2571-2587 17 p.

Research output: Contribution to journalArticle

Open Access
2013

Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials

Verbrugghen, T., Van Calenbergh, S., Vandurm, P., Pouyez, J., Wouters, J. & Maes, L., 10 Jan 2013, In : Journal of Medicinal Chemistry. 56, 1, p. 376-380 5 p.

Research output: Contribution to journalArticle

2012
4 Downloads (Pure)
Open Access
File
15 Downloads (Pure)
2011

Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors

Dolušić, E., Larrieu, P., Blanc, S., Sapunaric, F., Pouyez, J., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galleni, M., Frère, J-M., Masereel, B., Van Den Eynde, B., Wouters, J. & Frédérick, R., 2011, In : European Journal of Medicinal Chemistry. 46, 7, p. 3058-3065 8 p.

Research output: Contribution to journalArticle

Indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2,3 dioxygenase (IDO), a promising target for anti-cancer immunotherapy

Dolusic, E., Larrieu, P., Blanc, S., Moineaux, L., Sapunaric, F., Pouyez, J., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colau, D., Frère, J-M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2011, p. Book of Abstracts, 47èmes RICT, 6-8 juillet 2011, Lyon, France, IS08, p. 136. 1 p.

Research output: Contribution to conferencePoster

File
48 Downloads (Pure)
2010

Structural insights into the acidophilic pH adaptation of a novel endo-1,4-β-xylanase from Scytalidium acidophilum

Michaux, C., Pouyez, J., Mayard, A., Vandurm, P., Housen, I. & Wouters, J., 1 Oct 2010, In : Biochimie. 92, 10, p. 1407-1415 9 p.

Research output: Contribution to journalArticle

2008

Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate

De Ruyck, J., Pouyez, J., Rothman, S. C., Poulter, D. & Wouters, J., 2 Sep 2008, In : Biochemistry. 47, 35, p. 9051-9053 3 p.

Research output: Contribution to journalArticle

Protecting role of cosolvents in protein denaturation by SDS: A structural study

Michaux, C., Pouyez, J., Wouters, J. & Privé, G. G., 23 Jun 2008, In : BMC structural biology. 8, 29.

Research output: Contribution to journalArticle