JEAN-PASCAL PIRET

  • 1150 Citations
  • 15 h-Index
19992018
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Research Output 2001 2018

2018

A guide to nanosafety testing: Considerations on cytotoxicity testing in different cell models

Riebeling, C., Piret, J. P., Trouiller, B., Nelissen, I., Saout, C., Toussaint, O. & Haase, A., 1 Apr 2018, In : NanoImpact. 10, p. 1-10 10 p.

Research output: Contribution to journalArticle

Cytotoxicity
Nanoparticles
Assays
Testing
Dendritic Cells
2016

Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles

Piret, J. P., Bondarenko, O. M., Boyles, M. S. P., Himly, M., Ribeiro, A. R., Benetti, F., Smal, C., Lima, B., Potthoff, A., Simion, M., Dumortier, E., Leite, P. E. C., Balottin, L. B., Granjeiro, J. M., Ivask, A., Kahru, A., Radauer-Preiml, I., Tischler, U., Duschl, A., Saout, C. & 6 others, Anguissola, S., Haase, A., Jacobs, A., Nelissen, I., Misra, S. K. & Toussaint, O., 10 Dec 2016, (Accepted/In press) In : Archives of Toxicology. p. 1-16 16 p.

Research output: Contribution to journalArticle

Cytotoxicity
Nanoparticles
Assays
Inflammation
Caspase 7

Towards predicting the lung fibrogenic activity of MWCNT: Key role of endocytosis, kinase receptors and ERK 1/2 signaling

Vietti, G., Ibouraadaten, S., Palmai-Pallag, M., Yakoub, Y., Piret, J. P., Marbaix, E., Lison, D. & Van Den Brule, S., 20 Apr 2016, In : Nanotoxicology. 10, 4, p. 488-500 13 p.

Research output: Contribution to journalArticle

Fibroblasts
Endocytosis
Phosphotransferases
Lung
Carbon Nanotubes
2013
culture media
Dispersions
Nanoparticles
Culture Media
Assays
particle size distribution
dosage
oxides
cultured cells
centrifuges
21 Downloads (Pure)

Identification and localization of nanoparticles in tissues by mass spectrometry

Audinot, J-N., Georgantzopoulou, A., Piret, J-P., Gutleb, A. C., Dowsett, D., Migeon, H. N. & Hoffmann, L., 2013, In : Surface and interface analysis. 45, 1, p. 230-233 4 p.

Research output: Contribution to journalArticle

Mass spectrometry
mass spectroscopy
Tissue
Secondary ion mass spectrometry
Nanoparticles
7 Downloads (Pure)

Role of p38MAPK and oxidative stress in copper-induced senescence

Boilan, E., Winant, V., Dumortier, E., Piret, J-P., Bonfitto, F., Osiewacz, H. D., Debacq-Chainiaux, F. & Toussaint, O., 2013, In : Age. 35, 6, p. 2255-71 17 p.

Research output: Contribution to journalArticle

Copper
Oxidative Stress
Antioxidants
Copper Sulfate
Lipofuscin
2012
toxicology
Toxicology
Sonication
stirring
Dispersions
1 Downloads (Pure)

Copper(ii) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response

Piret, J-P., Jacques, D., Audinot, J-N., Mejia Mendoza, J. H., Boilan, E., Noël, F., Fransolet, M., Demazy, C., Lucas, S., Saout, C. & Toussaint, O., 21 Nov 2012, In : Nanoscale. 4, 22, p. 7168-7184 17 p.

Research output: Contribution to journalArticle

Oxidative stress
Copper oxides
Cytotoxicity
Nanoparticles
Chemical activation
1 Downloads (Pure)
Caco-2 Cells
Copper oxides
Hydrodynamics
Nanoparticles
Oxides
6 Downloads (Pure)
Carbon Nanotubes
Telomerase
Dispersions
Keratinocytes
Carbon nanotubes
1 Downloads (Pure)
Nanostructures
Nanostructured materials
Thrombin
Nanoparticles
Assays
2011
carbon nanotubes
cells
biological effects
stirring
liver
2010
Nanotubes
Carbon Nanotubes
Sonication
Cytotoxicity
Epidermis
1 Downloads (Pure)

Dispersion of multi-walled carbon nanotubes in biocompatible dispersants

Piret, J-P., Detriche, S., Vigneron, R., Vankoningsloo, S., Rolin, S., Mejia Mendoza, J. H., Masereel, B., Lucas, S., Delhalle, J., Luizi, F., Saout, C. & Toussaint, O., 2010, In : Journal of Nanoparticle Research. 12, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Multi-walled Carbon Nanotubes
Carbon Nanotubes
Nanotubes
Carbon nanotubes
Carbon
2008

Nanotoxico: Toxicological assessment of engineered nanoparticles using in vitro and in vivo models.

Rolin, S., Masereel, B., Vankoningsloo, S., Piret, J-P., Lucas, S. & Toussaint, O., 2008.

Research output: Contribution to conferencePaper

Risk assessment of nanoparticles on human health using in vitro models : a preliminary study

Piret, J-P., Vankoningsloo, S., Vigneron, R., Rolin, S., Saout, C., Masereel, B., Delhalle, J., Lucas, S. & Toussaint, O., 2008, 4th international congress of nanotechnology & clean tech 2007. 4th international congress of nanotechnology & clean tech 2007

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2006

Casein kinase 2 inhibition decreases hypoxia-inducible factor-1 activity under hypoxia through elevated p53 protein level

Hubert, A., Paris, S., Piret, J-P., Ninane, N., Raes, M. & Michiels, C., 2006, In : Journal of Cell Science. 119, 16, p. 3351-3362 12 p.

Research output: Contribution to journalArticle

Casein Kinase II
Hypoxia-Inducible Factor 1
Proteins
Cell Hypoxia
Null Lymphocytes

Hypoxia protects HepG2 cells against etoposide-induced apoptosis VIA a HIF-1-independent pathway

Piret, J-P., Cosse, J-P., Ninane, N., Raes, M. & Michiels, C., 2006, In : Experimental Cell Research. 312, 15, p. 2908-2920 13 p.

Research output: Contribution to journalArticle

Hep G2 Cells
Etoposide
Apoptosis
Transcription Factor AP-1
Transcription Factors

Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis

Piret, J-P., Minet, E., Cosse, J-P., Ninane, N., Debacq, C., Raes, M. & Michiels, C., 2005, In : Journal of Biological Chemistry. 280, 10, p. 9336-9344 9 p.

Research output: Contribution to journalArticle

Myeloid Cell Leukemia Sequence 1 Protein
tert-Butylhydroperoxide
Hypoxia-Inducible Factor 1
Cells
Apoptosis
2004

Caspase activation precedes PTP opening in TNF-α-induced apoptosis in L929 cells

Piret, J-P., Arnould, T., Fuks, B., Chatelain, P., Remacle, J. & Michiels, C., 2004, In : Mitochondrion. 3, 5, p. 261-278 18 p.

Research output: Contribution to journalArticle

Caspases
Tumor Necrosis Factor-alpha
Apoptosis
DNA Fragmentation
Caspase 8

Hypoxia and CoCl protect HepG2 cells against serum deprivation- and t-BHP-induced apoptosis: A possible anti-apoptotic role for HIF-1

Piret, J-P., Lecocq, C., Toffoli, S., Ninane, N., Raes, M. & Michiels, C., 2004, In : Experimental Cell Research. 295, 2, p. 340-349 10 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Hep G2 Cells
Apoptosis
Serum
Cell Hypoxia
tert-Butylhydroperoxide
Mitochondria
Hep G2 Cells
Hepatocellular Carcinoma
Permeability
2003

Soluble factors released by virus specific activated cytotoxic T-lymphocytes induce apoptotic death of astroglioma cell lines

Sabri, F., Chiodi, F., Piret, J-P., Wei, C-H., Major, E., Westermark, B., Masucci, M. G. & Levitsky, V., Apr 2003, In : Brain pathology (Zurich, Switzerland). 13, 2, p. 165-75 11 p.

Research output: Contribution to journalArticle

Astrocytoma
Cytotoxic T-Lymphocytes
Viruses
Cell Line
Lymphokines
2002
Hypoxia-Inducible Factor 1
Cell death
Hepatocellular Carcinoma
Cell Death
Cells

Is HIF-1α a pro- or an anti-apoptotic protein?

Piret, J-P., Mottet, D., Raes, M. & Michiels, C., 2002, In : Biochemical Pharmacology. 64, 5-6, p. 889-892 4 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Apoptosis Regulatory Proteins
Transcription Factors
Apoptosis
Gene Expression
2001

c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells

Minet, E., Michel, G., Mottet, D., Piret, J-P., Barbieux, A., Raes, M. & Michiels, C., 2001, In : Experimental Cell Research. 265, 1, p. 114-124 11 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Transcription Factor AP-1
Hep G2 Cells
Genes
Proto-Oncogene Proteins c-jun

HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: Role of MAP kinases

Michiels, C., Minet, E., Michel, G., Mottet, D., Piret, J-P. & Raes, M., 2001, In : IUBMB Life. 52, 1-2, p. 49-53 5 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Gene expression
Phosphotransferases
Chemical activation
Gene Expression