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Thesis

Analytical and clinical validation of sensitive assays for the diagnosis of immune heparin-induced thrombocytopenia

Author: Minet, V., 2017

Supervisor: Dogne, J. (Supervisor), Mullier, F. (External person) (Co-Supervisor), Laloy, J. (Jury), Lucas, S. (Jury), Masereel, B. (Jury), Chatelain, M. (External person) (Jury), Hoylaerts, M. F. (External person) (Jury) & Tardy, B. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

C. canimorsus interferes with coagulation by proteolytic cleavage of human coagulation factor X

Author: Hack, K., 12 Aug 2016

Supervisor: Cornelis, G. (Supervisor), Letesson, J. (President), Dogne, J. (Jury), Michiels, T. (External person) (Jury), Bogaerts, P. (External person) (Jury) & Chatelain, B. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Caractérisation structurale de la 5-lipoxygénase humaine et de son inhibition: support à la conception rationnelle d'inhibiteurs mixtes 5-LOX-COX-2

Author: Charlier, C., 15 Feb 2006

Supervisor: Wouters, J. (Supervisor), Durant, F. (Co-Supervisor), Dogne, J. (Jury), Vercauteren, D. (Jury), Hennichart, J. (External person) (Jury) & Moureau, F. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Design, synthesis and evaluation of coagulation FXIIa inhibitors as potential antithrombotic agents

Author: Bouckaert, C., 16 May 2017

Supervisor: Pochet, L. (Supervisor), Dogne, J. (Co-Supervisor), Lanners, S. (President), De Tullio, P. (External person) (Jury), Chatelain, C. (External person) (Jury) & TEN CATE, H. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Design, synthesis and pharmacological evaluation of carbonic anhydrase VII and IX inhibitors

Author: Thiry, A., 15 May 2008

Supervisor: Masereel, B. (Supervisor), Dogne, J. (Co-Supervisor), Wouters, J. (Jury), Feron, O. (Jury), Lambin, P. (Jury) & Flamion, B. (Jury)

Student thesis: Doc typesDoctor of Sciences

Design, synthesis molecular modelling and biological evaluation of modulators of the NF-kappa activation

Author: Mortier, J., 7 Jun 2010

Supervisor: Masereel, B. (Supervisor), Dogne, J. (President), Kiss, R. (External person) (Jury), Wouters, J. (Jury), Lambert De Rouvroit, C. (Jury), Wouters, J. (Jury) & WINUM, J. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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Development & validation of pharmacological tools for the preclinical testing of anticoagulants

Author: Robert, S., 7 Apr 2011

Supervisor: Pochet, L. (Supervisor), Dogne, J. (Co-Supervisor), Masereel, B. (President), Caron, N. (Jury), Chatelain, C. (External person) (Jury) & TEN CATE, H. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Effet de l'hypoxie intermittente sur l'expression génique et le phénotype angiogénique de cellules endothéliales

Author: Toffoli, S., 30 Oct 2009

Supervisor: Michiels, C. (Supervisor), Raes, M. (President), Matroule, J. (Jury), Dogne, J. (Jury) & Feron, O. (Jury)

Student thesis: Doc typesDoctor of Sciences

Etude de l'effet des agonistes du récepteur TP dans l'athérosclérose : effet du thromboxane et des isoprostanes sur les cellules musculaires lisses d'artère humaine

Author: Jacques, D., 2010

Supervisor: Dogne, J. (Supervisor) & Michiels, C. (Co-Supervisor)

Student thesis: Master typesMaster in Biochemistry and molecular and cellular Biology

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Etude des agonistes du récepteur TP dans un contexte athérogenèse : effets pro-inflammatoires et pro-migratoires du thromboxane A2 et de l'isoprostane sur les cellules musculaires lisses aortiques humaines

Author: Jadot, A., 2011

Supervisor: Dogne, J. (Supervisor) & Michiels, C. (Co-Supervisor)

Student thesis: Master typesMaster in Biochemistry and molecular and cellular Biology

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Étude des effets de radiations par rayons X ou par particules alpha sur les interactions entre cellules tumorales et cellules endothéliales

Author: Riquier, H., 28 Jan 2012

Supervisor: Michiels, C. (Supervisor), Lucas, S. (Jury), Dogne, J. (Jury), Renard, P. (President), Féron, O. (External person) (Jury) & PARIS, F. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Etude du rôle des médiateurs apparentés au thromboxane dans l'athérosclérose: effets de modulateurs originaux sur les cellules musculaires vasculaires

Author: Copine, C., 2009

Supervisor: Dogne, J. (Supervisor) & Michiels, C. (Co-Supervisor)

Student thesis: Master typesMaster in Biochemistry and molecular and cellular Biology

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Etude pharmacologique in vitro et ex vivo d'agents vasoactifs

Author: Belle, L., 2009

Supervisor: Dogne, J. (Supervisor) & Caron, N. (Co-Supervisor)

Student thesis: Master typesMaster in Biochemistry and molecular and cellular Biology

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Evaluation of thrombotic and/or bleeding risks associated with anticoagulotherapy.

Author: Douxfils, J., 24 Oct 2015

Supervisor: Dogne, J. (Supervisor), Mullier, F. (Supervisor), Masereel, B. (President), Chatelain, B. (Jury), Chatelain, C. (External person) (Jury), Verhamme, P. (External person) (Jury), TEN CATE, H. (External person) (Jury) & Ageno, W. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Evaluation pharmacologique de modulateurs de la cascade de l'acide arachidonique sue cellules endothéliales et dans un modèle murin d'athérosclérose.

Author: Genon, S., 2007

Supervisor: Dogne, J. (Co-Supervisor) & Masereel, B. (Supervisor)

Student thesis: Master typesMaster in Biology

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Ex vivo and in vivo evaluation of the potential toxicity of manufactured nanoparticles

Author: Laloy, J., 31 May 2012

Supervisor: Masereel, B. (Supervisor), Dogne, J. (President), Charlier, C. (External person) (Jury), Herin, M. (Jury), Lucas, S. (Jury) & Rolin, S. (Supervisor)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Identification de gènes impliqués dans les métastases induites par l'hypoxie, via l'analyse statistique et bioinformatique de banques de damiers à ADN, et confirmation de leur expression différentielle dans des modèles in silico

Author: De Meulder, B., 22 Jan 2013

Supervisor: Michiels, C. (Co-Supervisor), Depiereux, É. (Supervisor), Arnould, T. (President), Dogne, J. (Jury), De Bolle, X. (Jury), van HELDEN, J. (External person) (Jury) & Sonveaux, P. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

La dynamique de l'Hyaluronan dans les lésions d'ischémie-reperfusion rénale

Author: Decleves, A., 30 May 2008

Supervisor: Flamion, B. (Supervisor), Caron, N. (Co-Supervisor), Dogne, J. (Jury), Huynh-Thu, T. (Jury), Nortier, J. (External person) (Jury), Nonclercq, D. (External person) (Jury) & Bouby, N. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Modulation de la réponse des cellules cancéreuses à l'étoposide en normoxie ou hypoxie par des macrophages polarisés M1 ou M2

Author: Genin, M., 17 Dec 2014

Supervisor: Raes, M. (Supervisor), Michiels, C. (Supervisor), Gillet, J. (President), Dogne, J. (Jury), Moser, M. (External person) (Jury) & Noël, A. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

Monofunctionalizations of beta-cyclodextrin, conjugation with recognition patterns, and biological evaluation

Author: Bertolla, C., 28 Jun 2010

Supervisor: Masereel, B. (Supervisor), Pochet, L. (Co-Supervisor), Pirotte, B. (External person) (Jury), Goossens, J. (External person) (Jury), Dogne, J. (Jury) & Lambert De Rouvroit, C. (Jury)

Student thesis: Doc typesDoctor of Sciences

Optimization of the perioperative management of direct oral anticoagulants

Author: Lessire, S., 27 Oct 2016

Supervisor: Dogne, J. (Supervisor), Gourdin, M. (Co-Supervisor), Caron, N. (President), Masereel, B. (President), Chatelain, B. (Jury), Ickx, B. (External person) (Jury) & Samama, C. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

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Protection of Wistar-Furth rats from post-ischemic acute renal injury: a role for Nitric Oxide and Thromboxane?

Author: Voisin, V., 1 Jul 2014

Supervisor: Caron, N. (Supervisor), Poumay, Y. (President), Michiels, C. (Jury), Kirschvink, N. (Jury), Flamion, B. (Jury), Dogne, J. (Jury), Bouby, N. (External person) (Jury) & Nortier, J. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Quantification and characterization of microvesicles: applications in hereditary spherocytosis, type-II heparin-induced thrombocytopenia and cancer

Author: Mullier, F., 26 Mar 2012

Supervisor: Dogne, J. (Supervisor), Masereel, B. (President), Chatelain, B. (External person) (Co-Supervisor), Michiels, C. (Jury), Latinne, D. (External person) (Jury), Chatelain, C. (External person) (Jury), Wallemacq, P. (External person) (Jury), Harrison, P. (External person) (Jury) & Hoylaerts, M. F. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Roles of extracellular vesicles and their microRNA cargo in chemotherapeutic resistance, pro-coagulant phenotype and as potential biomarkers in diffuse large B-cell lymphoma

Author: Bouvy, C., 16 Oct 2017

Supervisor: Dogne, J. (Supervisor), Chatelain, C. (Co-Supervisor), Caron, N. (President), Graux, C. (Jury), Michiels, C. (Jury), Stamatopoulos, B. (External person) (Jury) & Ingrid, S. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences

Study of the effects of cycling hypoxia on endothelial cells and macrophages : a role in tumor-promoting inflammation

Author: Tellier, C., 26 Oct 2015

Supervisor: Michiels, C. (Supervisor), Letesson, J. (President), Dogne, J. (Jury), Raes, M. (Jury), Noël, A. (External person) (Jury), Féron, O. (External person) (Jury) & De Ridder, M. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences