Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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Development of new compounds targeting coagulation factor XIIa using innovative microfluidic assays in the context of fragment-based drug discovery
Davoine, C., POCHET, L. & Fillet, M.
1/10/18 → 30/09/20
Project: Research
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Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy
Davoine, C., Traina, A., Evrard, J., Lanners, S., Fillet, M. & Pochet, L., 5 Nov 2023, In: European Journal of Medicinal Chemistry. 259, 115636.Research output: Contribution to journal › Article › peer-review
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Capillary electrophoresis as a fragment screening tool to cross-validate hits from chromogenic assay: Application to FXIIa
Davoine, C., Fillet, M. & Pochet, L., 1 May 2021, In: Talanta. 226, p. 122163 122163.Research output: Contribution to journal › Article › peer-review
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Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa
Davoine, C., Pardo, A., Pochet, L. & Fillet, M., 9 Nov 2021, In: Analytical Chemistry. 93, 44, p. 14802-14809 8 p.Research output: Contribution to journal › Article › peer-review
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Factor XII/XIIa inhibitors: Their discovery, development, and potential indications
DAVOINE, C., BOUCKAERT, C., Fillet, M. & POCHET, L., 1 Dec 2020, In: European Journal of Medicinal Chemistry. 208, 112753.Research output: Contribution to journal › Review article › peer-review
Open AccessFile32 Downloads (Pure) -
Contribution au développement de nouveaux substrats en hydroxyéthylcellulose pour la spectroscopie Raman exaltée de surface: application au dosage de la dopamine
Davoine, C., 2018, (Unpublished)Research output: External Thesis › Master's Thesis
Activities
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Affinity Capillary Electrophoresis in Fragment-Based Drug Discovery Projects, a Tool for Hit Discovery and Binding Site Characterization
Clara DAVOINE (Speaker)
4 Jul 2022Activity: Talk or presentation types › Oral presentation
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6th EFMC-YSN MedChemBioOnline: PROTAC and Small Molecules Development
Clara DAVOINE (Participant)
28 Jan 2021Activity: Participating in or organising an event types › Participation in conference
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GIGA Doctoral School: Translational Research in Cardiovascular Diseases: from Biomarker-based Adaptive Explanatory Studies to Pragmatic Trials
Clara DAVOINE (Participant)
7 Dec 2020 → 9 Dec 2020Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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NovAliX Virtual Conference 2020
Clara DAVOINE (Participant)
28 Oct 2020Activity: Participating in or organising an event types › Participation in conference
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Mini-Symposium on -omics - Académie royale de Médecine
Clara DAVOINE (Participant)
29 Feb 2020Activity: Participating in or organising an event types › Participation in conference
Thesis
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Identification, characterization, and optimization of fragment hits against coagulation factor XIIa supported by affinity capillary electrophoresis and biochemical assay
Author: Davoine, C., 25 Apr 2023Supervisor: POCHET, L. (Supervisor), Fillet, M. (External person) (Co-Supervisor), Douxfils, J. (Jury), Frédérick, R. (External person) (Jury), Francotte, P. (External person) (Jury), Van Schepdael, A. (External person) (Jury) & Wätzig, H. (External person) (Jury)
Student thesis: Doc types › Doctor of Biomedical and Pharmaceutical Sciences
Press/Media
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Findings from University of Liege in the Area of Technology Reported (Advances In Analytical Technologies Detecting and Characterizing Noncovalent Interactions for Fragment-based Drug Discovery)
4/09/23
1 item of Media coverage
Press/Media: Expert Comment