Charles Nicaise — the Research Portal

Personal profile

Introduction

Assistant Professor, teaching General and Organ Histology at the Faculty of Medicine and Faculty of Sciences.

Group Leader at LNR - Laboratoire Neurodégénérescence et Régénération, member of URPhyM Research Unit and NARILIS.

Our activities are focused on the role of glial cells and glutamate transporters in CNS disorders such as osmotic demyelination syndrome (ODS) and spinal cord injuries.

Areas of expertise

Neurosciences

Neurodegenerative disorders : ALS, AD

CNS trauma : SCI

iPS, neural stem cell and glial precursor biology

Cell therapy

Neurosurgery on small animals

External responsibilities

Co-director of PFT Morph-IM (2017 - ...)

Member of the Board of B.S.C.D.B.

Member of the Belgian Society for Neuroscience

Member of the Board of Belgian Brain Council

Reviewer for F.R.S./F.N.R.S. and F.W.O.

Diplomas

2013 - Post-doctoral fellowship (CMMI, Erasme Hospital, Brussels, Belgium)

2011 - Post-doctoral fellowship (Thomas Jefferson University, Philadelphia, USA)

2010 - PhD Thesis (Université Libre de Bruxelles, Belgium)

2002 - MSc in Biomedical Sciences (Université Libre de Bruxelles, Belgium)

Education/Academic qualification

Doctor of the University, Université Libre de Bruxelles (ULB)

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Astrocytes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2017

3 Active

Study of the 3D arrangement of Phrenic Motor Neurons (PhMN) pool and their long-range neural connectivity in the healthy and injured mouse cervical spinal cord

Nicaise, C. & Fratini, M.

1/01/17 → …

Project: Research

Réalisation d'un atlas neuro-anatomique, histologique et fonctionnel de la moelle épinière humaine

Nicaise, C. & Jankovski, A.

1/10/13 → …

Project: Research

Caractérisation de modèles animaux de syndrome de démyélinisation osmotique

Bouchat, J. & Nicaise, C.

1/10/13 → …

Project: PHD

Research Output 2004 2019

1065 Citations
19 h-Index
40 Article
2 Conference contribution
2 Paper
2 Poster
3 More

Communication between the distal interphalangeal joint and the navicular bursa in the horse at Computed Tomography Arthrography

Hontoir, F., Rejas, E., Falticeanu, A., Nisolle, J-F., Simon, V., Nicaise, C., Clegg, P. & Vandeweerd, J-M., Jan 2019, In : Anat Histol Embryol. p. 1-9 9 p.

Research output: Contribution to journal › Article

Arthrography

ligaments

limbs (animal)

computed tomography

Horses

Regional oligodendrocytopathy and astrocytopathy precede myelin loss and blood–brain barrier disruption in a murine model of osmotic demyelination syndrome

Bouchat, J., Couturier, B., Marneffe, C., Gankam Kengne, F., Balau, B., De Swert, K., Poncelet, L., Brion, J. P., Gilloteaux, J. & Nicaise, C., 1 Mar 2018, In : Glia. 66, 3, p. 606-622 17 p.

Research output: Contribution to journal › Article

Demyelinating Diseases

Myelin Sheath

Blood-Brain Barrier

Oligodendroglia

Astrocytes

Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice

Vandeweerd, J-M., Hontoir, F., De Knoop, A., De Swert, K. & Nicaise, C., 22 Feb 2018, In : Journal of visualized experiments : JoVE. 132

Research output: Contribution to journal › Article

Motor Neurons

Diaphragm

Neurons

Cholera Toxin

Diaphragms

Sprimont L, Gilloteaux J, Bouchat J, Massie A and Nicaise C (2018). xCT/Slc7a11 deletion accelerates motor recovery and improves histological outcomes following cervical spinal contusion in mice

L, S., Gilloteaux, J., Bouchat, J., A, M. & Charles, N., 13 Aug 2018.

Research output: Contribution to conference › Paper

The leptin receptor mutation of the obese Zucker rat causes sciatic nerve demyelination with a centripetal pattern defect

Gilloteaux, J., Subramanian, K., Solomon, N. & Nicaise, C., 20 Oct 2018, In : Ultrastructural Pathology. 42, 5, p. 377-408 32 p.

Research output: Contribution to journal › Article

Zucker Rats

Leptin Receptors

Demyelinating Diseases

Sciatic Nerve

Myelin Sheath

Thesis

Animal models of mid-cervical spinal contusion : are they clinically-relevant ?

Author: Michel, S., 2014

Supervisor: Nicaise, C. (Supervisor), Saberi Minooee, K. (External person) (Jury), Abeloos, L. (External person) (Jury) & Bondue, B. (External person) (Jury)

Student thesis: Master types › Master