Charles Nicaise — the Research Portal

Personal profile

Introduction

Assistant Professor, teaching General and Organ Histology at the Faculty of Medicine and Faculty of Sciences.

Group Leader at LNR - Laboratoire Neurodégénérescence et Régénération, member of URPhyM Research Unit and NARILIS.

Our activities are focused on the role of glial cells and glutamate transporters in CNS disorders such as osmotic demyelination syndrome (ODS) and spinal cord injuries.

Areas of expertise

Neurosciences

Neurodegenerative disorders : ALS, AD

CNS trauma : SCI

iPS, neural stem cell and glial precursor biology

Cell therapy

Neurosurgery on small animals

External responsibilities

Co-director of PFT Morph-IM (2017 - ...)

Member of the Board of B.S.C.D.B.

Member of the Belgian Society for Neuroscience

Member of the Board of Belgian Brain Council

Reviewer for F.R.S./F.N.R.S. and F.W.O.

Diplomas

2013 - Post-doctoral fellowship (CMMI, Erasme Hospital, Brussels, Belgium)

2011 - Post-doctoral fellowship (Thomas Jefferson University, Philadelphia, USA)

2010 - PhD Thesis (Université Libre de Bruxelles, Belgium)

2002 - MSc in Biomedical Sciences (Université Libre de Bruxelles, Belgium)

Education/Academic qualification

Doctor of the University, Université Libre de Bruxelles (ULB)

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2017

3 Active

Study of the 3D arrangement of Phrenic Motor Neurons (PhMN) pool and their long-range neural connectivity in the healthy and injured mouse cervical spinal cord

Nicaise, C. & Fratini, M.

1/01/17 → …

Project: Research

Réalisation d'un atlas neuro-anatomique, histologique et fonctionnel de la moelle épinière humaine

Nicaise, C. & Jankovski, A.

1/10/13 → …

Project: Research

Caractérisation de modèles animaux de syndrome de démyélinisation osmotique

Bouchat, J. & Nicaise, C.

1/10/13 → …

Project: PHD

Research Output 2004 2017

1016 Citations
19 h-Index
37 Article
2 Conference contribution
1 Abstract
1 Paper
3 More

Regional oligodendrocytopathy and astrocytopathy precede myelin loss and blood–brain barrier disruption in a murine model of osmotic demyelination syndrome

Bouchat, J., Couturier, B., Marneffe, C., Gankam Kengne, F., Balau, B., De Swert, K., Poncelet, L., Brion, J. P., Gilloteaux, J. & Nicaise, C. 2017 In : Glia.

Research output: Contribution to journal › Article

Demyelinating Diseases

Myelin Sheath

Blood-Brain Barrier

Oligodendroglia

Astrocytes

Induced cell-based transplantation to therapeutically target spinal cord disorders

Nicaise, C. 1 May 2016 In : Current Stem Cell and Research Therapy. 11, 4, p. 300 1 p.

Research output: Contribution to journal › Editorial

Phagocyte-specific S100A8/A9 is upregulated in primary Sjögren's syndrome and triggers the secretion of pro-inflammatory cytokines in vitro

Nicaise, C., Weichselbaum, L., Schandene, L., Gangji, V., Dehavay, F., Bouchat, J., Balau, B., Vogl, T. & Soyfoo, M. S. 7 Oct 2016 In : Clinical and Experimental Rheumatology.

Research output: Contribution to journal › Article

Sjogren's Syndrome

Phagocytes

Cytokines

Blood Cells

Interleukin-17

Ultrastructural aspects of thalamus damages in a mouse model of osmotic demyelination syndrome: demyelination associated with oligodendrocyte injuries

Gilloteaux, J., Bouchat, J., Couturier, B., Gankam Kengne, F., Poncelet, O. & Nicaise, C. 2016

Research output: Contribution to conference › Paper

A novel murine model of osmotic demyelination syndrome

Bouchat, J., Couturier, B., Gankam Kengne, F. & Nicaise, C. 2015

Research output: Contribution to conference › Abstract

Demyelinating Diseases

Thalamus

Thesis

Animal models of mid-cervical spinal contusion : are they clinically-relevant ?

Author: Michel, S., 2014

Supervisor: Nicaise, C. (Supervisor), Saberi Minooee, K. (External person) (Jury), Abeloos, L. (External person) (Jury) & Bondue, B. (External person) (Jury)

Student thesis: Master types › Master

Do specific magnetic resonance and contrast enhanced computed tomography imaging provide early detection of cartilage changes after mechanical or chemical stimulation of the subchondral bone in an ovine model?

Author: Hontoir, F., 23 Aug 2018

Supervisor: Vandeweerd, J. (Supervisor), Clegg, P. (External person) (Co-Supervisor), Tew, S. (External person) (Jury), Nicaise, C. (Jury), Peffers, M. (External person) (Jury), Taylor, S. (External person) (Jury), Van Weeren, R. (External person) (Jury) & Tew, S. (External person) (Jury)

Student thesis: Doc types › Doctor of Veterinary Sciences

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