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Personal profile


Assistant Professor, teaching General and Organ Histology at the Faculty of Medicine and Faculty of Sciences.

Group Leader at LNR - Laboratoire Neurodégénérescence et Régénération, member of URPhyM Research Unit and NARILIS.

Our activities are focused on the role of glial cells and glutamate transporters in CNS disorders such as osmotic demyelination syndrome (ODS) and spinal cord injuries.

Areas of expertise


Neurodegenerative disorders : ALS, AD

CNS trauma : SCI

iPS, neural stem cell and glial precursor biology

Cell therapy

Neurosurgery on small animals

External responsibilities

Co-director of PFT Morph-IM (2017 - ...)

Member of the Board of B.S.C.D.B.

Member of the Belgian Society for Neuroscience

Member of the Board of Belgian Brain Council

Reviewer for F.R.S./F.N.R.S. and F.W.O.



2013 - Post-doctoral fellowship (CMMI, Erasme Hospital, Brussels, Belgium)

2011 - Post-doctoral fellowship (Thomas Jefferson University, Philadelphia, USA)

2010 - PhD Thesis (Université Libre de Bruxelles, Belgium)

2002 - MSc in Biomedical Sciences (Université Libre de Bruxelles, Belgium)

Education/Academic qualification

Doctor of the University, Université Libre de Bruxelles (ULB)

Fingerprint Dive into the research topics where Charles Nicaise is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
Motor Neurons Medicine & Life Sciences
Demyelinating Diseases Medicine & Life Sciences
Diaphragm Medicine & Life Sciences
Astrocytes Medicine & Life Sciences
Spinal Cord Injuries Medicine & Life Sciences
Contusions Medicine & Life Sciences
Myelin Sheath Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2017

Research Output 2004 2019

Communication between the distal interphalangeal joint and the navicular bursa in the horse at Computed Tomography Arthrography

Hontoir, F., Rejas, E., Falticeanu, A., Nisolle, J-F., Simon, V., Nicaise, C., Clegg, P. & Vandeweerd, J-M., 1 Mar 2019, In : Anat Histol Embryol. 48, 2, p. 133-141 9 p.

Research output: Contribution to journalArticle

limbs (animal)
computed tomography
5 Downloads (Pure)

Osmotic demyelination: From an oligodendrocyte to an astrocyte perspective

Nicaise, C., Marneffe, C., Bouchat, J. & Gilloteaux, J., 1 Mar 2019, In : International Journal of Molecular Sciences. 20, 5, 18 p., 1124.

Research output: Contribution to journalReview article

Open Access
Demyelinating Diseases

Ultrastructural Analysis of Thalamus Damages in a Mouse Model of Osmotic-Induced Demyelination

Bouchat, J., Gilloteaux, J., Suain, V., Van Vlaender, D., Brion, J. P. & Nicaise, C., 2019, In : Neurotoxicity Research. 36, 1, p. 144-162

Research output: Contribution to journalArticle

Open Access
Demyelinating Diseases
2 Downloads (Pure)

Regional oligodendrocytopathy and astrocytopathy precede myelin loss and blood–brain barrier disruption in a murine model of osmotic demyelination syndrome

Bouchat, J., Couturier, B., Marneffe, C., Gankam Kengne, F., Balau, B., De Swert, K., Poncelet, L., Brion, J. P., Gilloteaux, J. & Nicaise, C., 1 Mar 2018, In : Glia. 66, 3, p. 606-622 17 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Myelin Sheath
Motor Neurons
Cholera Toxin


Animal models of mid-cervical spinal contusion : are they clinically-relevant ?

Author: Michel, S., 2014

Supervisor: Nicaise, C. (Supervisor), Saberi Minooee, K. (External person) (Jury), Abeloos, L. (External person) (Jury) & Bondue, B. (External person) (Jury)

Student thesis: Master typesMaster

Imbalance between vasoactive substances in experimental Aristolochic Acid Nephropathy

Author: Jadot, I., 2019

Supervisor: Caron, N. (Supervisor), Decleves, A. (Co-Supervisor), Michiels, C. (President), Nicaise, C. (Jury), Nortier, J. (External person) (Jury), Colet, J. (External person) (Jury) & Chatziantoniou, C. (External person) (Jury)

Student thesis: Doc typesDoctor of Biomedical and Pharmaceutical Sciences