Projects per year
Personal profile
Introduction
Assistant Professor, teaching General and Organ Histology at the Faculty of Medicine and Faculty of Sciences.
Group Leader at LNR - Laboratoire Neurodégénérescence et Régénération, member of URPhyM Research Unit and NARILIS.
Our activities are focused on the role of glial cells and glutamate transporters in CNS disorders such as osmotic demyelination syndrome (ODS) and spinal cord injuries.
Areas of expertise
Neurosciences
Neurodegenerative disorders : ALS, AD
CNS trauma : SCI
iPS, neural stem cell and glial precursor biology
Cell therapy
Neurosurgery on small animals
External responsibilities
Co-director of PFT Morph-IM (2017 - ...)
Member of the Board of B.S.C.D.B.
Member of the Belgian Society for Neuroscience
Member of the Board of Belgian Brain Council
Reviewer for F.R.S./F.N.R.S. and F.W.O.
Diplomas
2013 - Post-doctoral fellowship (CMMI, Erasme Hospital, Brussels, Belgium)
2011 - Post-doctoral fellowship (Thomas Jefferson University, Philadelphia, USA)
2010 - PhD Thesis (Université Libre de Bruxelles, Belgium)
2002 - MSc in Biomedical Sciences (Université Libre de Bruxelles, Belgium)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of the University, This work was aimed at developing effective strategies for amyotrophic lateral sclerosis (ALS) repair using neural precursor cell transplantation (derived from adult neural stem cells or human induced-pluripotent stem cells) and characterizing the blood-brain barrier of the SOD1G93A rat model of ALS., Université Libre de Bruxelles
Award Date: 30 Jun 2010
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Collaborations and top research areas from the last five years
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Development of 3D-brain organoids in the context of SARS-CoV-2 infection
16/01/23 → …
Project: Research
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Développement de motoneurones phréniques à partir de cellules souches pluripotentes induites
1/02/22 → …
Project: Research
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Deciphering entry mechanisms and axoplasmic transport of SARS-CoV-2 from peripheral nerve endings
1/01/22 → 31/12/23
Project: Research
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Neurofilament accumulations in amyotrophic lateral sclerosis patients’ motor neurons impair axonal initial segment integrity
Lefebvre-Omar, C., Liu, E., Dalle, C., d’Incamps, B. L., Bigou, S., Daube, C., Karpf, L., Davenne, M., Robil, N., Jost Mousseau, C., Blanchard, S., Tournaire, G., Nicaise, C., Salachas, F., Lacomblez, L., Seilhean, D., Lobsiger, C. S., Millecamps, S., Boillée, S. & Bohl, D., Jun 2023, In: Cellular and Molecular Life Sciences. 80, 6, 150.Research output: Contribution to journal › Article › peer-review
Open Access -
Volumetry of ovine incisors dental pulp for further regenerative therapy
Ems, G., Severino, L., NISOLLE, J-F., Nicaise, C., Lambrichts, I., LO MONACO, MELISSA., Bronckaers, A., Vandeweerd, J-M. & Hontoir, F., Jun 2023, In: Anatomia, Histologia, Embryologia. 2023Research output: Contribution to journal › Article › peer-review
Open Access -
Dental pulp in regenerative therapy: Description and characterization of dental pulp stem cells isolated from incisors of a pre-clinical model of osteoarthritis
Severino, L., Ems, G., Nisolle, J-F., Nicaise, C., Vandeweerd, J-M. & Hontoir, F., 2022.Research output: Contribution to conference › Poster › peer-review
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SV2A PET imaging is a non-invasive marker for the detection of spinal damages in experimental models of spinal cord injury
Bertoglio, D., Halloin, N., De Lombaerde, S., Jankovski, A., Verhaeghe, J., Nicaise, C. & Staelens, S., 1 Aug 2022, In: Journal of nuclear medicine. 63, 8, p. 1245-1251 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
A primary cilium in oligodendrocytes: a fine structure signal of repairs in thalamic Osmotic Demyelination Syndrome (ODS)
GILLOTEAUX, J., Bouchat, J., Bielarz, V., Brion, J-P. & Nicaise, C., 2021, In: Ultrastructural Pathology. 45, 2, p. 128-157 30 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Viral entry inhibitors protect against SARS-CoV-2-induced neurite shortening in differentiated SH-SY5Y cells
Nicaise, C. (Creator), Mignolet, M. (Creator), GILLOTEAUX, J. (Creator) & Gueibe, M. (Creator), University of Namur, 24 Aug 2023
Dataset
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The cystine/glutamate xCT antiporter: yet another glial glutamate transporter modulating recovery following spinal cord injury?
Charles Nicaise (Speaker)
21 May 2022Activity: Talk or presentation types › Invited talk
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Non coding RNA in health and disease
Charles Nicaise (Organiser), Patricia Renard (Organiser), Benoit Muylkens (Organiser), Denis L. J. Lafontaine (Organiser) & Virginie Van Scherpenzeel Thim (Organiser)
18 Mar 2022Activity: Participating in or organising an event types › Participation to a Symposium, a study Day
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Role of Cystine/glutamate antiporter in the spinal cord
Charles Nicaise (Speaker)
13 Mar 2022Activity: Talk or presentation types › Invited talk
Equipment
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Atomic force microscope
Charles Nicaise (Manager) & Francesca Cecchet (Manager)
Technological Platform Morphology - ImagingFacility/equipment: Equipment
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BD Pathway 855
Charles Nicaise (Manager) & Francesca Cecchet (Manager)
Technological Platform Morphology - ImagingFacility/equipment: Equipment
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Confocal microscope
Charles Nicaise (Manager) & Francesca Cecchet (Manager)
Technological Platform Morphology - ImagingFacility/equipment: Equipment
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Digital holographic microscope
Charles Nicaise (Manager) & Francesca Cecchet (Manager)
Technological Platform Morphology - ImagingFacility/equipment: Equipment
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FACS
Charles Nicaise (Manager) & Francesca Cecchet (Manager)
Technological Platform Morphology - ImagingFacility/equipment: Equipment