Projects per year
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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Development of new compounds targeting coagulation factor XIIausing innovative microfluidic assays in the context of fragment-based drug discovery
Davoine, C. (PI) & Pochet, L. (Supervisor)
1/10/20 → 30/09/22
Project: Research
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Development of new compounds targeting coagulation factor XIIa using innovative microfluidic assays in the context of fragment-based drug discovery
Davoine, C. (PI), Pochet, L. (Supervisor) & Fillet, M. (CoI)
1/10/18 → 30/09/20
Project: Research
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Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery
Davoine, C., Pochet, L. & Fillet, M., Sept 2023, In: TrAC : Trends in Analytical Chemistry. 166, p. 117161 1 p., 117161.Research output: Contribution to journal › Article › peer-review
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Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy
Davoine, C., Traina, A., Evrard, J., Lanners, S., Fillet, M. & Pochet, L., 5 Nov 2023, In: European Journal of Medicinal Chemistry. 259, 115636.Research output: Contribution to journal › Article › peer-review
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Capillary electrophoresis as a fragment screening tool to cross-validate hits from chromogenic assay: Application to FXIIa
Davoine, C., Fillet, M. & Pochet, L., 1 May 2021, In: Talanta. 226, p. 122163 122163.Research output: Contribution to journal › Article › peer-review
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Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa
Davoine, C., Pardo, A., Pochet, L. & Fillet, M., 9 Nov 2021, In: Analytical Chemistry. 93, 44, p. 14802-14809 8 p.Research output: Contribution to journal › Article › peer-review
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Factor XII/XIIa inhibitors: Their discovery, development, and potential indications
DAVOINE, C., BOUCKAERT, C., Fillet, M. & POCHET, L., 1 Dec 2020, In: European Journal of Medicinal Chemistry. 208, 112753.Research output: Contribution to journal › Review article › peer-review
Open AccessFile112 Downloads (Pure)
Activities
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Affinity Capillary Electrophoresis in Fragment-Based Drug Discovery Projects, a Tool for Hit Discovery and Binding Site Characterization
DAVOINE, C. (Speaker)
4 Jul 2022Activity: Talk or presentation types › Oral presentation
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6th EFMC-YSN MedChemBioOnline: PROTAC and Small Molecules Development
DAVOINE, C. (Participant)
28 Jan 2021Activity: Participating in or organising an event types › Participation in conference
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GIGA Doctoral School: Translational Research in Cardiovascular Diseases: from Biomarker-based Adaptive Explanatory Studies to Pragmatic Trials
DAVOINE, C. (Participant)
7 Dec 2020 → 9 Dec 2020Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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NovAliX Virtual Conference 2020
DAVOINE, C. (Participant)
28 Oct 2020Activity: Participating in or organising an event types › Participation in conference
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Mini-Symposium on -omics - Académie royale de Médecine
DAVOINE, C. (Participant)
29 Feb 2020Activity: Participating in or organising an event types › Participation in conference
Thesis
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Identification, characterization, and optimization of fragment hits against coagulation factor XIIa supported by affinity capillary electrophoresis and biochemical assay
Davoine, C. (Author), POCHET, L. (Supervisor), Fillet, M. (Co-Supervisor), Douxfils, J. (Jury), Frédérick, R. (Jury), Francotte, P. (Jury), Van Schepdael, A. (Jury) & Wätzig, H. (Jury), 25 Apr 2023Student thesis: Doc types › Doctor of Biomedical and Pharmaceutical Sciences
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