• 5260 Citations
  • 40 h-Index
1989 …2020

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2017

A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis

Carvalho, A., Chu, J., Meinguet, C., Kiss, R., Vandenbussche, G., Masereel, B., Wouters, J., Kornienko, A., Pelletier, J. & Mathieu, V., 15 Jun 2017, In : European Journal of Pharmacology. 805, p. 25-35 11 p.

Research output: Contribution to journalArticle

Data in support of a harmine-derived beta-carboline in vitro effects in cancer cells through protein synthesis

Carvalho, A., Chu, J., Meinguet, C., Kiss, R., Vandenbussche, G., Masereel, B., Wouters, J., Kornienko, A., Pelletier, J. & Mathieu, V., 1 Jun 2017, In : Data in Brief. 12, p. 546-551 6 p.

Research output: Contribution to journalArticle

2015

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties

Meinguet, C., Bruyère, C., Frédérick, R., Mathieu, V., Vancraeynest, C., Pochet, L., Laloy, J., Mortier, J., Wolber, G., Kiss, R., Masereel, B. & Wouters, J., 13 Apr 2015, In : European Journal of Medicinal Chemistry. 94, p. 45-55 11 p., 7726.

Research output: Contribution to journalArticle

Open Access
2014
2013

Indoleamine 2,3-Dioxygenase Inhibitory Activity of Derivatives of Marine Alkaloid Tsitsikammamine A

Dolusic, E., Larrieu, P., Meinguet, C., Colette, D., Rives, A., Blanc, S., Ferain, T., Pilotte, L., Stroobant, V., Wouters, J., Van den Eynde, B., Masereel, B., Delfourne, E. & Frédérick, R., 1 Jan 2013, In : Bioorganic and medicinal chemistry letters. 23, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

3 Downloads (Pure)

New selective carbonic anhydrase IX inhibitors: Synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides

Rogez-Florent, T., Meignan, S., Foulon, C., Six, P., Gros, A., Bal-Mahieu, C., Supuran, C. T., Scozzafava, A., Frédérick, R., Masereel, B., Depreux, P., Lansiaux, A., Goossens, J. F., Gluszok, S. & Goossens, L., 15 Mar 2013, In : Bioorganic and Medicinal Chemistry. 21, 6, p. 1451-1464 14 p.

Research output: Contribution to journalArticle

2012

Antibody-functionalized polymer-coated gold nanoparticles targeting cancer cells: an in vitro and in vivo study

Marega, R., Karmani, L., Flamant, L., Nageswaran, P. G., Valembois, V., Masereel, B., Feron, O., Vander Borght, T., Lucas, S., Michiels, C., Gallez, B. & Bonifazi, D., 2012, In : Journal of Materials Chemistry. 22, 39, p. 21305-21312 8 p.

Research output: Contribution to journalArticle

Open Access
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Novel trisubstituted harmine derivatives with original in vitro anticancer activity

Frédérick, R., Bruyére, C., Vancraeynest, C., Reniers, J., Meinguet, C., Pochet, L., Backlund, A., Masereel, B., Kiss, R. & Wouters, J., 26 Jul 2012, In : Journal of Medicinal Chemistry. 55, 14, p. 6489-6501 13 p.

Research output: Contribution to journalArticle

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Pilotte, L., Larrieu, P., Stroobant, V., Colau, D., Dolušić, E., Frédérick, R., De Plaen, E., Uyttenhove, C., Wouters, J., Masereel, B. & Van Den Eynde, B. J., 14 Feb 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 7, p. 2497-2502 6 p.

Research output: Contribution to journalArticle

Open Access
File
57 Downloads (Pure)

Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles

Moineaux, L., Laurent, S., Reniers, J., Dolusic, E., Galleni, M., Frère, J-M., Masereel, B., Frédérick, R. & Wouters, J., 1 Aug 2012, In : European Journal of Medicinal Chemistry. 54, p. 95-102 8 p.

Research output: Contribution to journalArticle

Open Access
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141 Downloads (Pure)
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2011

Antibody immobilization on gold nanoparticles coated layer-by-layer with polyelectrolytes

Masereel, B., Dinguizli, M., Moniotte, N., Bouzin, C., Feron, O., Gallez, B., Vander Borght, T., Michiels, C. & Lucas, S., 1 Apr 2011, In : Journal of Nanoparticle Research. 13, 4, p. 1573-1580 8 p.

Research output: Contribution to journalArticle

Anti-virulence strategy against Brucella suis: Synthesis, biological evaluation and molecular modeling of selective histidinol dehydrogenase inhibitors

Abdo, M-R., Turtaut, F., Montero, J-L., Winum, J-Y., Joseph, P., Köhler, S., Mortier, J. & Masereel, B., 21 May 2011, In : Organic and Biomolecular Chemistry. 9, 10, p. 3681-3690 10 p.

Research output: Contribution to journalArticle

BM-573 inhibits the development of early atherosclerotic lesions in Apo e deficient mice by blocking TP receptors and thromboxane synthase

Cherdon, C., Ooms, A., Sakalihassan, N., Defraigne, J-O., Rolin, S., Michiels, C., Masereel, B., Dogné, J-M., Hanson, J., Pirotte, B., De Leval, L. & Drion, P., 2011, In : Prostaglandins and Other Lipid Mediators. 94, p. 124-132 9 p.

Research output: Contribution to journalArticle

Carbon nanoparticles synthesized by sputtering and gas condensation inside a nanocluster source of fixed dimension

Bouchat, V., Feron, O., Gallez, B., Masereel, B., Michiels, C., Vander Borght, T., Rossi, F. & Lucas, S., 2011, In : Surface and Coatings Technology. 205, S2, p. S577-S581

Research output: Contribution to journalArticle

4 Downloads (Pure)

Chemical reactivity of Plasma Polymerized Allylamine (PPAA) thin films on Au and Si: study of the thickness influence and ageing of the films

Moreau, N., Feron, O., Gallez, B., Masereel, B., Michiels, C., Vander Borght, T., Rossi, F. & Lucas, S., 25 Jul 2011, In : Surface and Coatings Technology. 205, SUPPL. 2, p. S462-S465

Research output: Contribution to journalArticle

Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors

Dolušić, E., Larrieu, P., Blanc, S., Sapunaric, F., Pouyez, J., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galleni, M., Frère, J-M., Masereel, B., Van Den Eynde, B., Wouters, J. & Frédérick, R., 2011, In : European Journal of Medicinal Chemistry. 46, 7, p. 3058-3065 8 p.

Research output: Contribution to journalArticle

Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors

Dolušić, E., Larrieu, P., Blanc, S., Sapunaric, F., Norberg, B., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galeni, M., Frre, J. M., Masereel, B., Van Den Eynde, B., Wouters, J. & Frédérick, R., 15 Feb 2011, In : Bioorganic and Medicinal Chemistry. 19, 4, p. 1550-1561 12 p.

Research output: Contribution to journalArticle

File
542 Downloads (Pure)

On the use of radioisotopes to study the possible synthesis by magnetron sputtering of bimetallic nanoparticles

Bouchat, V., Moreau, N., Valembois, V., Abbas, K., Feron, O., Gallez, B., Holzwartz, U., Masereel, B., Michiels, C., Simonelli, F., Vander Borght, T. & Lucas, S., 25 Aug 2011, In : Surface and Coatings Technology. 205, 21-22, p. 4934-4940 7 p.

Research output: Contribution to journalArticle

Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation

Dubois, L., Peeters, S., Lieuwes, N. G., Geusens, N., Thiry, A., Wigfield, S., Carta, F., McIntyre, A., Scozzafava, A., Dogné, J-M., Supuran, C. T., Harris, A. L. & Masereel, B., Jun 2011, In : Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 99, 3, p. 424-31 8 p.

Research output: Contribution to journalArticle

Surface properties and cell adhesion onto allylamine-plasma and amine-plasma coated glass coverslips

Crespin, M., Moreau, N., Masereel, B., Feron, O., Gallez, B., Vander Borght, T., Michiels, C. & Lucas, S., Mar 2011, In : Journal of Materials Science: Materials in Medicine. 22, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators

Dolušić, E., Larrieu, P., Moineaux, L., Stroobant, V., Pilotte, L., Colau, D., Pochet, L., Van Den Eynde, B., Masereel, B., Wouters, J. & Frédérick, R., 11 Aug 2011, In : Journal of Medicinal Chemistry. 54, 15, p. 5320-5334 15 p.

Research output: Contribution to journalArticle

2010

Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

Maresca, A., Temperini, C., Pochet, L., Masereel, B., Scozzafava, A. & Supuran, C., 2010, In : Journal of Medicinal Chemistry. 53, p. 335-344 10 p.

Research output: Contribution to journalArticle

Design, solid-phase synthesis and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors

Gluszok, S., Frédérick, R., Foulon, C., Klupsch, F., Supuran, C., Vullo, D., Scozzafava, A., Goossens, J-F., Masereel, B., Depreux, P. & Goossens, L., 2010, In : Bioorganic and Medicinal Chemistry. 18, 21, p. 7392-7401 10 p.

Research output: Contribution to journalArticle

Dispersion of multi-walled carbon nanotubes in biocompatible dispersants

Piret, J-P., Detriche, S., Vigneron, R., Vankoningsloo, S., Rolin, S., Mejia Mendoza, J. H., Masereel, B., Lucas, S., Delhalle, J., Luizi, F., Saout, C. & Toussaint, O., 2010, In : Journal of Nanoparticle Research. 12, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

1 Downloads (Pure)

NF-κB inducing kinase (NIK) inhibitors: Identification of new scaffolds using virtual screening

Mortier, J., Masereel, B., Frederick, R., Remouchamps, C., Ganeff, C. & Piette, J., 1 Aug 2010, In : Bioorganic and medicinal chemistry letters. 20, 15, p. 4515-4520 6 p.

Research output: Contribution to journalArticle

Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-κB activation

Mortier, J., Frederick, R., Pochet, L., Wouters, J., Masereel, B., Ganeff, C., Remouchamps, C., Piette, J., Dejardin, E. & Talaga, P., 15 May 2010, In : Biochemical Pharmacology. 79, 10, p. 1462-1472 11 p.

Research output: Contribution to journalArticle

Radioimmunotherapy with radioactive nanoparticles: Biological doses and treatment efficiency for vascularized tumors with or without a central hypoxic area

Bouchat, V., Michiels, C., Masereel, B., Feron, O., Gallez, B., Vander Borght, T. & Lucas, S., 2010, In : Medical physics. 37, 4, p. 1826-1839 14 p.

Research output: Contribution to journalArticle

2009

Conception et synthèse d'indanesulfonamides en tant qu'inhibiteurs originaux des anhydrases carboniques

Thiry, A., Dogné, J-M. & Masereel, B., 2009, In : Chimie nouvelle. 100, p. 22-25 4 p.

Research output: Contribution to journalArticle

Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2009, In : Pharmacological Research. 59, 3, p. 160-166 7 p.

Research output: Contribution to journalArticle

Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors

Thiry, A., Ledecq, M., Cecchi, A., Frederick, R., Dogné, J. M., Supuran, C. T., Wouters, J. & Masereel, B., 15 Jan 2009, In : Bioorganic and Medicinal Chemistry. 17, 2, p. 553-557 5 p.

Research output: Contribution to journalArticle

PVD synthesis and transfer into water-based solutions of functionalized gold nanoparticles

Moreau, N., Michiels, C., Masereel, B., Feron, O., Gallez, B., Vander Borght, T. & Lucas, S., 2009, In : Plasma Processes and Polymers . 6, SUPPL. 1, p. S888-S892

Research output: Contribution to journalArticle

1 Downloads (Pure)

Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors

Thiry, A., Delayen, A., Goossens, L., Houssin, R., Ledecq, M., Frankart, A., Dogné, J-M., Wouters, J., Supuran, C. T., Hénichart, J-P. & Masereel, B., 1 Feb 2009, In : European Journal of Medicinal Chemistry. 44, 2, p. 511-8 8 p.

Research output: Contribution to journalArticle