• 5260 Citations
  • 40 h-Index
1989 …2020

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2014

Thiosemicarbazide Derivatives as Novel Indolamine-2,3-dioxygenase (IDO) Inhibitors

Serra, S., Moineaux, L., Vancraeynest, C., Masereel, B., Pochet, L., Wouters, J. & Frédérick, R., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 280

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2011

coauthor on lecture: Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase (TDO): discovery of an orally active TDO inhibitor.

Dolusic, E., Larrieu, P., Moineaux, L., Stroobant, V., Pilotte, L., Colau, D., Van den Eynde, B., Masereel, B., Wouters, J. & Frédérick, R., 2011, Book of Abstracts, Emerging Targets and Treatments: Opportunities and Challenges for Drug Design, Ghent, 25 November 2011: Annual One-Day Meeting on Medicinal Chemistry of SRC & KVCV (MedChem 2011). Vol. OC01. p. OC01

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Indoleamine 2,3-Dioxygenase Inhibitory Activity of Derivatives of Marine Alkaloid Tsitsikammamine A

Dolusic, E., Larrieu, P., Colette, D., Blanc, S., Rives, A., Fraser, G., Wouters, J., Kiss, R., Van den Eynde, B., Masereel, B., Delfourne, E. & Frédérick, R., 2011, Oral Communication, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège: De la conception à la réalisation en pharmacochimie. Vol. OC10. p. 22-22 1 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

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2009

Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs ?

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2009, Abstract book - Annual Meeting of Belgian Society on Thrombosis and Haemostasis.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2008

A potential new drug delivery system for cancer therapy: biotin-labelled beta-cyclodextrin.

Bertolla, C., Robert, S., Pochet, L. & Masereel, B., 2008, Abstract book - Small Molecules, Antibodies and Natural Products: Multiple Faces of Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Application of the boron neutron capture therapy to the carbonic anhydrase IX

Deglim, J., Thiry, A., Wouters, J. & Masereel, B., 2008, Abstract book - XIII International Conference on Boron Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Design, synthesis and pharmacological evaluation of novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors.

Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2008, Abstract book - Small Molecules, Antibodies and Natural Products: Multiple Faces of Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Risk assessment of nanoparticles on human health using in vitro models: a preliminary study

Piret, J-P., Vankoningsloo, S., Vigneron, R., Rolin, S., Saout, C., Masereel, B., Delhalle, J., Lucas, S. & Toussaint, O., 2008, 4th international congress of nanotechnology & clean tech 2007. International Association of Nanotechnology

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2007

Application of the boron neutron capture therapy to the carbonic anhydrases

Deglim, J., Thiry, A., Wouters, J. & Masereel, B., 2007, Abstract Book-13th Belgian Forum of Pharmaceutical Sciences.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Beta-cyclodextrin coupled to oxytocine: synthesis and pharmacological evaluation of a new potential drug carrier system

Bertolla, C., Rolin, S., Pochet, L. & Masereel, B., 2007, Abstract Book-13th Belgian Forum of Pharmaceutical Sciences.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Carbonic anhydrase inhibitors: synthesis, biological evaluation and rational drug design to target the tumor-associated CA IX

Thiry, A., Ledecq, M., Dogné, J-M., SUPURAN, C. T., Wouters, J. & Masereel, B., 2007, Abstract Book-13th Belgian Forum of Pharmaceutical Sciences.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Le profil d'activité de thrombine: un puissant test de criblage ex vivo pour le développement d'agents anticoagulants

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, Abstract Book-21èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Microwave assisted medicinal chemistry: application to the synthesis of coumarins and cyclodextrins

Bertolla, C., Robert, S., Pochet, L. & Masereel, B., 2007, Abstract Book-New Drugs and Drug Candidates: Recent Achievements in Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Nouveaux senseurs chimiques à base de beta-cyclodextrines comportant un motif coumarine. Synthèse, détermination structurale et étude des variations spectroscopiques

Bertolla, C., Pochet, L. & Masereel, B., 2007, Abstract Book-21ème Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Nouvelles coumarines 3-carboxamides en tant qu'inhibiteurs de facteur XIIa

Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2007, Abstract Book-21èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Pharmacological evaluation of 6-chloromethyl-coumarins bearing a basic moiety in the 3-position as new anticoagulant drugs

Robert, S., Frédérick, R., Masereel, B., Dogné, J-M. & Pochet, L., 2007, Abstract Book-New Drugs and Drug Candidates: Recent Achievements in Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Thrombin activity profile: a powerful ex vivo screening test for the development of anticoagulant drugs

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, Abstract Book-XXIst Congress of the International Society on Thrombosis and Haemostasis.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Thrombin activity profile: a rapid, reliable and relevant ex vivo screening test for the development of anticoagulant drugs

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, Abstract Book-13th Belgian Forum of Pharmaceutical Sciences.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Towards new leads for selective carbonic anhydrase IX inhibition: synthesis, pharmacological evaluation and combined ligand-based and target-based approach

Thiry, A., Ledecq, M., Dogné, J-M., SUPURAB, C. T., Wouters, J. & Masereel, B., 2007, Abstract Book-New Drugs and Drug Candidates : Recent Achievements in Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2006

Développement d'inhibiteurs sélectifs de thrombine : optimisation du substituant en position P1

Robert, S., Frédérick, R., Masereel, B. & Pochet, L., 2006, Abstract Book-20èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Évaluation pharmacologique de la beta-cyclodextrin couplée à l'ocytocine en tant que nouveau véhicule moléculaire

Bertolla, C., Rolin, S., Pochet, L. & Masereel, B., 2006, Abstract Book - XXèmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2005

Developpement d'indanesulfonamides inhibiteurs de l'anhydrase carbonique IX

Thiry, A., Ledecq, M., Chazalette, C., Wouters, J., SUPURAN, C. T. & Masereel, B., 2005, Abstract Book-19èmes Journées Franco-Belge de pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Évaluation biologique de coumarines en tant qu'inhibiteurs du complexe facteur tissulaire/facteur VIIa

Robert, S., Frédérick, R., Masereel, B. & Pochet, L., 2005, Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Purification de beta-cyclodextrines monofonctionnalisées par chromatographie échangeuse ionique : étude comparative

Bertolla, C., Murray, A-M., Pochet, L. & Masereel, B., 2005, Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Structure-based design of coumarins as potent thrombin inhibitors

Frédérick, R., Robert, S., Charlier, C., De Ruyck, J., Masereel, B. & Pochet, L., 2005, Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2004

Coumarins as inhibitors of serine proteases of the coagulation cascade

Frédérick, R., Robert, S., Charlier, C., Masereel, B. & Pochet, L., 2004, Abstract Book-XVIIIth International Symposium on Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Coumarins as serine protease inhibitors

Pochet, L., Frédérick, R., Robert, S., Rolin, S. & Masereel, B., 2004, Abstract Book-XVIIIth International Symposium on Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Étude du mode d'interaction de coumarines avec la thrombine

Frédérick, R., Charlier, C., De Ruyck, J., Dieu, M., Robert, S., Masereel, B. & Pochet, L., 2004, Abstract Book-18èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Évaluation biologique de dérivés coumariniques en tant qu'inhibiteurs de protéases à sérine de la cascade de la coagulation

Robert, S., Frédérick, R., Masereel, B. & Pochet, L., 2004, Abstract Book-18èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Evaluation pharmacologique chez le cobaye d'une sulfonylurée originale (BM-520) apparentée au torasémide en tant qu'antagoniste du récepteur du TXA2.

Vastersaegher, C., Dogné, J-M., Hanson, J., Masereel, B. & Rolin, S., 2004, Abstract book - XVIIIèmes journées franco-belges de pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Nouveaux dérivés cyanoguanidines de beta-cyclodextrines

Bertolla, C., Pochet, L. & Masereel, B., 2004, Abstract Book-18ème Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Synthesis of new cyanoguanidine beta-cyclodextrin derivatives

Bertolla, C., Pochet, L. & Masereel, B., 2004, Abstract Book-12th International Cyclodextrin Symposium.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2003

Effect of BM-573, a dual TXA2 synthase inhibitor and TXA2 receptor antagonist on infarct size in a porcine model of coronary thrombosis induced by ferric chloride.

Rolin, S., Dogné, J-M., Pétein, M., Delarge, J. & Masereel, B., 2003, Abstract book - Meeting de la Société Belge de Physiologie et de Pharmacologie Fondamentales et Cliniques.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Synthèse de beta-cyclodextrines modifiées

Bertolla, C., Piette, M., Evrard, B., Delattre, L., Piel, G., Frédérick, R. & Masereel, B., 2003, Abstract Book-17èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2001

Biological evaluation of a novel sulfonylurea, BM-567, with a dual activity on thromboxane A2 synthase and receptor

Rolin, S., Dogné, J-M., de Leval, X., Delarge, J. & Masereel, B., 2001, Abstract book - 10ème Forum de la Société Belge des Sciences Pharmaceutiques.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Comparaison de l'effet de deux dérivés de l'acide 6-(acétoxyméthyl)-2-oxo-2H-1-benzopyrane-3-carboxylique sur l'inhibition de l'invasion cellulaire in vitro et in vivo

Kempen, I., Pochet, S., Papapostolou, D., Counerotte, S., Masereel, B., Foidart, J-M., Reboud-Ravaux, M., Frankenne, F. & Pirotte, B., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 73

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Dérivés pyridiniques et benzéniques de l'amiloride : synthèse et évaluation pharmacologique exploratoire en tant qu'inhibiteurs de l'échange sodium-proton

Laeckmann, D., Rogister, F., Delarge, J. & Masereel, B., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 74

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Effects of thromboxane A2 receptor antagonists and COX inhibitors on osteogenic sarcoma cell-induced platelet aggregation

de Leval, X., Delarge, J., Neven, P., Michaux, C., Masereel, B., Pirotte, B., David, J-L. & Dogné, J-M., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie.. Universitaires, P. & Namur, D. (eds.). p. 69

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

In vitro biological evaluation of two cyclooxygenase-2 inhibitors

Rolin, S., Michiels, C., Masereel, B., de Leval, X., Durant, F. & Michaux, C., 2001, Abstract book - XIVèmes Journées franco-belges de pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Pharmacological effect of BM-593, a novel sulfonylurea acting as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor on human platelets and isolated smooth muscles

Rolin, S., Dogné, J-M., Delarge, J. & Masereel, B., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 78

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Pharmacological effects of BM-593, a novel sulfonylurea acting as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor on human platelets and isolated smooth muscles.

Rolin, S., Delarge, J., Masereel, B. & Dogné, J-M., 2001, Abstract book - XVèmes Journées franco-belges de pharmacochimie. p. 78

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Pharmacological profile of BM-567, a novel thromboxane A2 receptor antagonist and thromboxane A2 receptor antagonist and thromboxane A2 synthase inhibitor on the human platelets and isolated smooth muscles

Rolin, S., Dogné, J-M., Delarge, J. & Masereel, B., 2001, Abstract book - Meeting de la Société Belge de Physiologie et de Pharmacologie Fondamentales et Cliniques.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Préparation et évaluation pharmacologique d'analogues benzéniques de l'amiloride substitués sur l'azote distal de la foncxtion acylguanidine en tant qu'inhibiteurs de l'échange sodium-calcium

Laeckmann, D., Rogister, F., Delarge, J. & Masereel, B., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 75

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Synthèse et évaluation enzymatique de nouvelles coumarines en tant qu'inhibiteurs de thrombine

Pochet, L., Doucet, C., Pirotte, B., Frédérick, R., Delarge, J., Reboud-Ravaux, M. & Masereel, B., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 60

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Synthèse et évaluation pharmacologique d'un méthanesulfonamide pyridinique apparenté à l'acide niflumique

Julémont, F., de Leval, X., Neven, P., Devel, P., Pirotte, B., Delarge, J., Masereel, B., Michaux, C. & Dogné, J-M., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. universitaires, P. & Namur, D. (eds.). p. 49

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Towards new leads for selective cyclooxygenase-2 (COX-2) inhibition

Michaux, C., Rolin, S., de Leval, X., Masereel, B., Durant, F. & Wouters, J., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 84

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2000

BM-531, a novel sulfonylurea acting as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor

Rolin, S., Dogné, J-M., Delarge, J. & Masereel, B., 2000, Abstract book - XIVèmes Journées franco-belges de pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

BM-573, a novel potent dual acting agent for thromboxane A2 receptor antagonism and thromboxane A2 synthase inhibition

Rolin, S., Dogné, J-M., Delarge, J. & Masereel, B., 2000, Abstract book-9ème Forum de la Société Belge des Sciences Pharmaceutiques.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

1999

Antiplatelet properties of BM-519, a novel combined thromboxane A (2) receptor antagonist and thromboxane synthase inhibitor.

Dogne, JM., de Leval, X., Delarge, J., Neven, P., Rolin, S., David, JL., Fillet, G. & Masereel, B., 1999, BLOOD. Vol. 94. p. 103B-103B

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Evaluation d'une nouvelle sulfonylcyanoguanidine en tant qu'antagoniste du thromboxane A2.

Rolin, S., Dogné, J-M., Neven, P., de Leval, X., Delarge, J. & Masereel, B., 1999, Abstract book - XIIIèmes Journées franco-belges de pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution