URPHYM

Projects

Projects per year 1963 2001 2003 2005 2019 2022 2025

• 3 Not started
• 32 Active
• 84 Finished

Projects per year

Search results

• Active

  Development of 3D-brain organoids in the context of SARS-CoV-2 infection

  Mignolet, M. & Nicaise, C.

  16/01/23 → …

  Project: Research

• From the identification of pathogenic autoantibodies in patients with neurological post-acute sequelae of COVID-19 to mechanisms of neuronal-derived neoantigen production

  Mignolet, M., Nicaise, C. & Gillet, N.

  16/01/23 → …

  Project: PHD

  • Neoantigen 100%
  • Autoantibodies 100%
  • Central Nervous System 100%
  • Antigen 100%
  • Severe Acute Respiratory Syndrome Coronavirus 2 100%

• reDox: Regulation of the synthesis of the epitranscriptomic modification dihydrouridine (D) during an oxidative stress

  Hermand, D.

  1/01/23 → 31/12/24

  Project: Research

• PGCspecification: Specification of precursor germ cells (PGC) from somatic cells during early embryogenesis in C. elegans

  PONSARD, P. & Hermand, D.

  1/10/22 → 30/09/24

  Project: Research

  • Caenorhabditis elegans 100%
  • Cyclin-Dependent Kinase 100%
  • Embryogenesis 100%
  • Germ Cell 100%
  • Somatic Cell 100%

• Deciphering the CTD code of RNA polymerase II in healthy and cancer cells

  Hermand, D., Bachand, F. & Jacques, P. É.

  1/09/22 → 31/08/25

  Project: Research

  • Heptad Repeat 100%

• Dihydrouridine: Epitranscriptomic of dihydrouridine in pro- and eukarya

  Hermand, D. & Hallez, R.

  1/01/22 → 31/12/23

  Project: Research

• Observing life in 4D and high resolution for the characterization of novel dynamic biological mechanisms

  Renard, H., Declèves, A., Hermand, D. & Poumay, Y.

  1/01/22 → 31/12/23

  Project: Research

• Drosha homolog Pac1 functions in microRNA-like biogenesis and cellular differentiation control in fission yeast S. pombe

  Yague-Sanz, C. & Hermand, D.

  1/10/21 → 30/09/24

  Project: Research

  • Drosha 100%
  • Ribonuclease 14%
  • RNA Structure 14%

• SoGerSpe: Soma-Germline specification during embryogenesis in C. elegans

  Hermand, D.

  1/01/21 → 1/12/24

  Project: Research

  • Germline 100%
  • Embryogenesis 100%
  • Caenorhabditis Elegans 100%
  • Germ Cell 100%
  • Precursor 75%

• Improve the diagnosis and treatment of esophageal cancer by identifying circulating tumour DNA and characterizing genome alterations leading to treatment failure.

  Gillet, J., Laes, J. F. & LEFEVRE, S.

  1/04/20 → 31/03/24

  Project: Research

• MycEpi: Développement et validation d’un modèle multivalent de dermatophytose in vitro, en vue de son exploitation analytique, diagnostique et pharmacologique

  Poumay, Y. & Faway, E.

  1/01/20 → 31/12/23

  Project: Research

  • Bacterial Spore 100%
  • Dermatophyte 100%
  • Dermatophytosis 100%
  • Spore 100%
  • Arthroconidia 66%

• Surface analysis of reconstructed human epidermis, with a focus on Atopic Dermatitis inflammatory condition

  Houssiau, L., Delvaux, X. & Poumay, Y.

  1/09/19 → …

  Project: PHD

• Study of the 3D arrangement of Phrenic Motor Neurons (PhMN) pool and their long-range neural connectivity in the healthy and injured mouse cervical spinal cord

  Nicaise, C. & Fratini, M.

  1/01/17 → …

  Project: Research

• keratinocyte senescence

  Poumay, Y.

  6/12/13 → …

  Project: Research

• Implication d’un gène candidat dans la chimiorésistance de lignées issues de carcinomes spinocellulaires en conditions hypoxiques

  Graux, C. & Poumay, Y.

  1/12/13 → …

  Project: Research

• Réalisation d'un atlas neuro-anatomique, histologique et fonctionnel de la moelle épinière humaine

  Nicaise, C. & Jankovski, A.

  1/10/13 → …

  Project: Research

• Caractérisation de modèles animaux de syndrome de démyélinisation osmotique

  Bouchat, J. & Nicaise, C.

  1/10/13 → …

  Project: PHD

• Télévie: Study of the function of the TMEM45A protein that has been identified in the resistance of cancer cells to chemotherapeutic agents

  MICHIELS, C. & Charlier, C.

  1/01/13 → …

  Project: PHD

  • Tissue (Anatomy) 100%
  • Cancer Resistance 100%
  • Cancer Cell Line 100%
  • Anticarcinogen 100%
  • Transcriptome 75%

• Differentiation modulation of cancer and normal keratinocyte by inflammation

  Hermant, M. & Poumay, Y.

  14/03/12 → …

  Project: PHD

• PK study in normal and nephrectomized rabbits

  Caron, N.

  15/03/08 → …

  Project: Research

• Characterization of the lysosomal membrane protein p40 : study of the phenotype of mutant mice

  Boonen, M., Jadot, M. & Lambert De Rouvroit, C.

  1/01/08 → …

  Project: Research

• FRFC: Evaluation de rôle "suppresseur de tumeur" de MAged1. Identification de partenaires de Maged2 par la méthode des doubles hybrides dans la levure.

  De Backer, O.

  23/12/06 → …

  Project: Research

• Involvement of lysosomes in apoptosis

  De Coninck, S., Jadot, M. & Wattiaux, R.

  15/08/05 → …

  Project: Research

  • Programmed Cell Death 100%
  • Lysosome 100%
  • Cell Death 100%
  • Apoptosis 100%
  • Liver Lysosome 50%

• FSR: Caractérisation du déficit apoptotiques observés dans des souris déficientes en Maged1.

  De Backer, O.

  3/07/05 → …

  Project: Research

• Inter-organelle communication between mitochondria and lysosomes : a proteomic approach

  Arnould, T., Hamer, I. & Jadot, M.

  1/01/05 → …

  Project: Research

  • Mitochondria 100%
  • Proteomics 100%
  • Sterol Regulatory Element-Binding Protein 50%
  • Cholesterol 50%
  • Sterol Regulatory Element Binding Protein 1a 25%

• Hyaluronidase 1 intracellular trafficking

  Jadot, M., Boonen, M., Dogne, S. & Flamion, B.

  3/09/04 → …

  Project: Research

  • Hyaluronidase 100%
  • Intracellular Trafficking 100%
  • Anabolism 50%
  • Biosynthesis 50%

• Etude de la fonction de Maged 2 IN VIVO. Analyse de souris knock-out Maged d2

  De Backer, O. & DOMBRET, C.

  1/01/04 → …

  Project: PHD

  • Knock Out 100%

• Rôle de l'hyaluronane et de ses partenaires dans les lésions d'ischémie-réperfusion rénales. Utilisation d'un modèle murin

  DECLEVES, A. & Flamion, B.

  1/01/04 → …

  Project: PHD

• Distribution and function of Hyal-1, a putative lysosomal hydrolase

  THIRION, J., GASINGIRWA, M. & Jadot, M.

  1/11/03 → …

  Project: PHD

• FSR: Etude in vitro de la fonction des protéines MAGE

  De Backer, O.

  3/07/03 → …

  Project: Research

• Study op p40, a novel protein of the lysosomal membrane

  Boonen, M., Jadot, M., Lambert De Rouvroit, C. & Tevel, V.

  1/01/03 → …

  Project: Research

  • Protein 100%
  • Membrane 100%

• Centrifugation methods applied to the preparation and analysis of lysosomal fractions

  Jadot, M., THIRION, J. & DAUTRELOUX, A.

  1/01/63 → …

  Project: PHD

  • Centrifugation 100%
• Not started

  The MAS project : Measure And See the activity of direct oral anticoagulant in the clinical context

  Douxfils, J. & MULLIER, F.

  Project: Research

• PROJET PUNCH: Premiers pas dans la démarche clinique en bachelier de médecine : savoir faire et savoir être

  MARCHAND, E., Givron, H. & Desseilles, M.

  Project: Research

• Modifications structurelles et fonctionnelles des microdomaines membranaires lipidiques au cours de la sénescence du kératinocyte

  Warnon, C., Debacq-Chainiaux, F. & Poumay, Y.

  Project: PHD

• Finished

  Plateforme technologique d’excellence interuniversitaire sur les méthodes alternatives à l'expérimentation animale

  Renard, H., Arnould, T., Muylkens, B., Nicaise, C., Vandeweerd, J., SU, B. L. & Poumay, Y.

  1/12/22 → 30/06/23

  Project: Research

• Transcriptional control of a developmenal transition in Caenorhabditis elegans

  Stubbe, F. & Hermand, D.

  1/01/22 → 30/09/23

  Project: Research

• Identification of chemical inhibitors of Elongator to counteract resistance to conventional therapies in BRAFV600E melanoma

  TRICQUET, P. & Hermand, D.

  1/10/21 → 30/09/23

  Project: Research

• Projet interdisciplinaire « Hector Lebrun » : mobilités, réseaux et engagements d’un homme de sciences (1866-1960)

  Roekens, A., Poumay, Y. & Rase, C.

  1/10/20 → 1/10/22

  Project: Research

• PGCspecification: Specification of precursor germ cells (PGC) from somatic cells during early embryogenesis in C. elegans

  PONSARD, P. & Hermand, D.

  1/10/20 → 30/09/22

  Project: Research

  • Caenorhabditis elegans 100%
  • Germ Cell 100%
  • Somatic Cell 100%
  • Cyclin-Dependent Kinase 100%
  • Germline 60%

• EpiD: Epitranscriptomic of dihydrouridine

  Hermand, D.

  1/01/20 → 31/12/21

  Project: Research

  • Epitranscriptomics 100%
  • Dihydrouridine 100%
  • Synthase 28%
  • Mutant 28%
  • Synthetase 28%

• Deciphering the regulation of Elongator-dependent tRNA modification by the TOR pathway

  Hermand, D.

  1/10/19 → 30/09/21

  Project: Research

• FSR-Cofin privé: Alternate receptors for IL-4/IL-13 in atopic dermatitis (FSR Part)

  Poumay, Y. & Progneaux, A.

  1/10/19 → 30/09/22

  Project: Research

  • Atopic Dermatitis 100%
  • Interleukin 13 100%

• Transcriptional control of a developmenal transition in Caenorhabditis elegans

  Stubbe, F. & Hermand, D.

  1/10/19 → 31/12/21

  Project: Research

• Alternate receptors for IL-4/IL-13 in atopic dermatitis

  Poumay, Y.

  1/09/19 → 31/08/21

  Project: Research

• Analyzing the role of multiple receptors of interleukins 4 and 13 in atopic dermatitis

  Progneaux, A. & Poumay, Y.

  14/01/19 → 30/09/19

  Project: Research

  • Interleukin Derivative 100%
  • Atopic Dermatitis 100%
  • Interleukin 13 100%
  • Interleukin 4 100%
  • Agonist 9%

• Is a trafficking defect between endolysosomes and lysosomes the underlying cause of spastic paraplegia 21?

  Boonen, M.

  1/01/19 → 31/12/20

  Project: Research

• Erasmus+ICM: PROJECT FOR HIGHER EDUCATION STUDENT AND STAFF MOBILITY BETWEEN PROGRAMME COUNTRIES AND PARTNER COUNTRIES

  Gillet, J.

  1/06/17 → 28/07/19

  Project: Research

• Bourse post-doc 24 mois

  BAUER, F. & Hermand, D.

  15/04/17 → 14/04/19

  Project: Research

• Does RNA Polymerase II prime the chromatin at tRNA genes for RNA Polymerase III Transcription? Renewal

  Yague-Sanz, C. & Hermand, D.

  1/01/17 → 30/09/18

  Project: Research