Research Output 1989 2019

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2019
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Comparison of the impact of DOACs on hemostasis diagnostic tests

Siriez, R., Evrard, J., Dogne, J-M., Mullier, F. & Douxfils, J., 2019, Comparison of the impact of DOACs on hemostasis diagnostic tests.

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Impact of betrixaban on chromogenic anti-Xa assays - Methodologies improvements

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Bouvy, C., Lessire, S., Mullier, F. & Douxfils, J., 2019, (En attente de publication).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

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2018

Betrixaban: Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and Practice in thrombosis and haemostasis. Issue S1 ed. Vol. Volume 2. PB364

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Betrixaban : Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, BJH - Belgian Journal of Hematology - Clinic: Abstracts - 33rd General Annual Meeting of the Belgian Hematology Society . p. 22 42 p. PP47

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Betrixaban: Impact on routine and specific coagulation assays - Practical laboratory guidance

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, International Society for Laboratory Hematology: Abstracts.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Clot waveform analysis: Determination of optimal wavelength to assess the fibrin coagulation process

Evrard, J., Siriez, R., Bouvy, C., Laloy, J., Mullier, F., Dogne, J-M. & Douxfils, J., 5 Jul 2018, JTH-Journal of Thrombosis and haemostasis: Research and practice of thrombosis and haemostasis. issue S1 ed. Vol. 2. PB385

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Clot waveform analysis for measuring and quantifying fibrin clot formation

Evrard, J., Siriez, R., Themans, P., Laloy, J., Mullier, F., Dogne, J-M. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and pratice in thrombosis and haemostasis. issue S1 ed. Vol. 2. PB582

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5 Downloads (Pure)

In Vitro Effects of BCR-ABL Tyrosine Kinase Inhibitors on Endothelial Cells Survival and Functions

Haguet, H., Douxfils, J., Chatelain, C., GRAUX, C., Mullier, F. & Dogne, J-M., 5 Jul 2018, Special Issue: Abstracts of the 64th Annual Meeting of the Scientific Standardization Committee of the International Society on Thrombosis and Haemostasis, July 18–21, 2018. p. 242 1 p. PB497. (Research and Practice in Thrombosis and Haemostasis; vol. 2, no. S1).

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Open Access
File
Protein-Tyrosine Kinases
Cell Survival
Endothelial Cells
E-Selectin
Vascular Cell Adhesion Molecule-1

Numerical forecasts for lab experiments constraining modified gravity: The chameleon model

Schlögel, S., Clesse, S. & Füzfa, A., 1 Jan 2018, 14th Marcel Grossman Meeting On Recent Developments in Theoretical and Experimental General Relativity, Astrophysics and Relativistic Field Theories, Proceedings. Ruffini, R., Bianchi, M., Ruffini, R. & Jantzen, R. T. (eds.). World Scientific Publishing Co Pte Ltd, p. 1259-1264 6 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

vacuum chambers
forecasting
gravitation
relativity
interferometry
2017
3 Downloads (Pure)

A New Method for Determining Concentrations of Direct Oral Anticoagulants

Bloemen, S., Zwaveling, S., Douxfils, J., Peters, T., Wagenvoord, R., Hemker, H. C., Mullier, F., de Laat, B., Roest, M. & Kremers, R., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 968 1 p.

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Open Access
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Circulating microRNAs as biomarkers in diffuse large B-cell lymphoma: a pilot prospective longitudinal clinical study

Bouvy, C., Wannez, A., Chatelain, C. & Dogne, J-M., May 2017, 22nd Congress Of The European Hematology Association Madrid, Spain, June 22–25, 2017.

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5 Downloads (Pure)

Efficacy of a Novel Contact Pathway Inhibitor, Ir-CPI, on in vitro Clotting Induced by PCI Catheter Segment

Douxfils, J., Gheldof, D., Derochette, S., Tassignon, J., Meinguet, C., Guyaux, M., Dogne, J-M. & Godfroid, E., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 1044-1045 2 p.

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Open Access
File
8 Downloads (Pure)

Heparin Calibrated Anti-Xa Assays for the Measurement of Low Levels of Direct Factor Xa Inhibitors

Sabor, L., Raphaël, M., Dogne, J-M., Mullier, F. & Douxfils, J., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 1044 1 p.

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Open Access
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Impact of BCR-ABL Tyrosine Kinase Inhibitors on Atherosclerosis Plaque Rupture

Haguet, H., Douxfils, J., Chatelain, C. J., Graux, C., Mullier, F. & Dogné, J-M., 2017, Abstract and Meeting Program of the 59th ASH Annual Meeting. Suppl 1 ed. Vol. 130. p. 1591-1591 1 p. (Blood).

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Protein-Tyrosine Kinases
Rupture
Atherosclerosis
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9

In Vitro Effects of BCR-ABL Tyrosine Kinase Inhibitors on Endothelial Cells Survival and Functions

Haguet, H., Douxfils, J., Chatelain, C. J., Graux, C., Mullier, F. & Dogné, J-M., 2017, Abstract and Meeting Program of the 59th ASH Annual Meeting. Suppl 1 ed. Vol. 130. p. 1592-1592 1 p. (Blood).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Protein-Tyrosine Kinases
Cell Survival
Endothelial Cells
Atherosclerosis
E-Selectin
2 Downloads (Pure)

Measurement of Direct Oral Anticoagulants Levels in Patients Admitted for Bleeding Events: A Prospective Study

Sennesael, A-L., Larock, A-S., Douxfils, J., Dogne, J-M., Spinewine, A. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. p. 989 1 p.

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Open Access
File
1 Downloads (Pure)

Patients on a Fixed Dose of DOAC: What Percentage is in the Therapeutic Window?

Hemker, H. C., Bloemen, S., Kremers, R., Kelchtermans, H., Douxfils, J., Mullier, F. & de Laat, B., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 986-987 2 p.

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Open Access
File
11 Downloads (Pure)

Stability of TGA Parameters in Patients Treated with Anticoagulants Using the Fully Automated ST-Genesia System

Douxfils, J., Nicolas, J-B., Larock, A-S., Devalet, B., Vandermeeren, Y., Gérard, V., Guldenpfennig, M., De Fays, K., Baudar, J. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 513-514 2 p.

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Open Access
File
23 Downloads (Pure)

Standardization and Automation of Thrombin Generation Assay: on the Way to the Clinical Lab

Douxfils, J., Baudar, J., Guldenpfennig, M., Chatelain, B., Nicolas, J-B. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 507 1 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access
File
2 Downloads (Pure)

The Impact of the Eculizumab on the Thrombogenicity Induced by Extracellular Vesicles in Paroxysmal Nocturnal Hemoglobinuria Patients

Wannez, A., Devalet, B., Bouvy, C., Bihin, B., Douxfils, J., Dogne, J-M. & Mullier, F., 2017, Research and practice in thrombosis and haemostasis: Abstracts of the XXVI Congress of the International Society on Thrombosis and Haemostasis, July 8–13, 2017. Vol. 1. p. 1083 1 p.

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Open Access
File
2016

Application of a clot based assay to measure the procoagulant activity of stored allogeneic red blood cell concentrates

Devalet, B., Wannez, A., Bailly, N., Alpan, L., Gheldof, D., Douxfils, J., Deneys, V., Bihin, B., Chatelain, B., Dogne, J-M., Chatelain, C. & Mullier, F., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 142 1 p. VAS26

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

Cardiovascular effect of BCR-ABL TKIs: a meta-analysis and systematic review of arterial and venous occlusive events

Haguet, H., Mullier, F., Chatelain, C., Graux, C., Dogné, J-M. & Douxfils, J., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 77 1 p. HEM08

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

Estimation of rivaroxaban plasma concentrations in the perioperative setting with or without heparin bridging: an ex vivo study using dedicated chromogenic assays

Lessire, S., Douxfils, J., Pochet, L., Dincq, A-S., Larock, A-S., Gourdin, M., Dogné, J-M., Chatelain, B. & Mullier, F., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 21 1 p. CA30

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

Impact of apixaban on the Dilute Russell’s viper venom time: an ex-vivo study

Sennesael, A-L., Lessire, S., Chatelain, B., Larock, A-S., Dogné, J-M., Spinewine, A., Mullier, F. & Douxfils, J., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 9 1 p. CA05

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

Matrix effect of commercially available direct oral anticoagulant standards: a look through the limits and the need for standardization of current calibrators

Douxfils, J., Legrand, H., Sennesael, A-L., Lessire, S., Dincq, A-S., Larock, A-S., Chatelain, B., Dogne, J-M. & Mullier, F., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 30 1 p. CA-54

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access

Transfer of Multidrug Resistance Among Acute Myeloid Leukemia Cells Via Extracellular Vesicles and Their Micrornas Cargo

Bouvy, C., Wannez, A., Chatelain, C. & Dogne, J-M., 1 Dec 2016, 58th ASH Annual Meeting: Annual Meeting Abstracts. Blood ed. Vol. 128.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2015

A DRVVT-based assay to estimate the intensity of anticoagulation in patients treated with NOACS

Sennesael, A-L., Douxfils, J., Exner, T., Larock, A-S., Dogné, J-M., Spinewine, A. & Mullier, F., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015.. p. 798 1 p. PO125-WED

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

BCR-ABL Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: A Systematic Review and Meta-Analysis on the Risk of Cardiovascular Events, Major Molecular Response and Overall Survival

Douxfils, J., Haguet, H., Chatelain, C., Graux, C. & Dogne, J-M., 4 Dec 2015, Blood - 2015 ASH Annual Meeting Abstracts. Vol. 126. p. 2785 - 2785 1 p.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

C. canimorsus affects coagulation by proteolytic cleavage of factor X

Hack, K., Douxfils, J., Dogné, J-M. & Cornelis, G., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015.. p. 616 1 p. PO299-TUE

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Impact of edoxaban on a large panel of routine of more specific coagulation assays

Douxfils, J., Del Bianco, T., Baudar, J., Lessire, S., Chatelain, B., Dogné, J-M. & Mullier, F., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015.. p. 297 1 p. PO092-MON

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Impact of edoxaban on haemostasis diagnosis assays: practical recommendations

Douxfils, J., Del Bianco, T., Baudar, J., Lessire, S., Chatelain, B., Dogné, J-M. & Mullier, F., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20-25, 2015.. p. 531 1 p. PO063-TUE

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Risk of cardiovascular events associated with BCR-ABL TKIs: a systematic review and meta-analysis

Douxfils, J., Haguet, H., Mullier, F., Chatelain, C., Graux, C. & Dogné, J-M., 2015, J Thromb Haemost. 2015 Jun;13 Suppl 2:1-997. doi: 10.1111/jth.12993.: Special Issue: Abstracts of the XXV Congress of the International Society on Thrombosis and Haemostasis, June 20–25, 2015. p. 141-142 2 p. OR126

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2014

Estimation of dabigatran plasma concentrations in the perioperative setting. An ex-vivo study using dedicated coagulation assays.

Douxfils, J., Lessire, S., Dincq, A-S., Gourdin, M., Baudar, J., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, Blood - 2014 ASH Annual Meeting Abstracts. Vol. 124.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Fragment Expansion of 2,5-Dichlorophenyl to Discover New FXIIa Inhibitors

Bouckaert, C., Serra, S., Frédérick, R. & Pochet, L., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 229

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Interest of thrombin time in the periprocedural management for patients on dabigatran etexilate

Douxfils, J., Remacle, S., Lessire, S., Dincq, A-S., Gourdin, M., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, Journal of Thrombosis and Haemostasis. 2014 Jun;12 Suppl 1:1-117.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

INTEREST OF THROMBIN TIME IN THE PERI-PROCEDURAL MANAGEMENT FOR PATIENTS ON DABIGATRAN ETEXILATE

Remacle, S., Lessire, S., Douxfils, J., Dincq, A-S., Gourdin, M., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY. Vol. 36. p. 95-95

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Thiosemicarbazide Derivatives as Novel Indolamine-2,3-dioxygenase (IDO) Inhibitors

Serra, S., Moineaux, L., Vancraeynest, C., Masereel, B., Pochet, L., Wouters, J. & Frédérick, R., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 280

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

What is the best time sampling for the two direct oral anticoagulants (DOACs), dabigatran and rivaroxaban?

Douxfils, J., Baudar, J., Devalet, B., Samama, M. M., Chatelain, B., Dogne, J-M. & Mullier, F., 2014, Journal of Thrombosis and Haemostasis. 2014 Jun;12 Suppl 1:1-117.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2013

Acustar HIT-IGG and heparin-induced multiple electrode aggregometry: a useful combination for rapid diagnosis of type-II HIT

Minet, V., Douxfils, J., Bailly, N., Osselaer, J-C., Chatelain, C., Elalamy, I., Chatelain, B., Dogne, J-M. & Mullier, F., 2013, Journal of Thrombosis and Haemostasis. 2013 Dec;11 Suppl 3:1-105.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Dabigatran Etexilate and Risk Of Myocardial Infarction, Major Bleeding and All-Cause Mortality: A Systematic Review and Meta-Analysis Of Randomized Controlled Trials

Douxfils, J., Buckinx, F., Mullier, F., Minet, V., Rabenda, V., Reginster, J-Y., Hainaut, P., Bruyère, O. & Dogne, J-M., 2013, Blood 2013 122:3633; published ahead of print December 6, 2013.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Design and synthesis of thiosemicarbazides as inhibitors of Arginase I, a therapeutic target for anticancer immunotherapy

Colette, C., Vancraeynest, C., Serra, S., Pochet, L. & Frédérick, R., 2013, 2013 Book of Abstracts, 27èmes Journées franco-belges de Pharmacochimie / 21èmes Conférences européennes du GP2A. p. 45

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Impact of CYP3A4*1G Polymorphism on plasmatic concentration profile of rivaroxaban (Xarelto) assessed by coagulation assays

Douxfils, J., Mullier, F., Chatelain, C., Chatelain, B. & Dogne, J-M., 2013, Journal of Thrombosis and Haemostasis. 2013 Dec;11 Suppl 3:1-105.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Laboratory recommendations for the monitoring of dabigatran

Douxfils, J., Mullier, F., Chatelain, C., Robert, S., Chatelain, B. & Mullier, F., 2013, Journal of Thrombosis and Haemostasis. 2013 Dec;11 Suppl 3:1-105.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Laboratory recommendations for the monitoring of rivaroxaban

Douxfils, J., Mullier, F., Chatelain, C., Robert, S., Chatelain, B. & Mullier, F., 2013, Journal of Thrombosis and Haemostasis. 2013 Dec;11 Suppl 3:1-105.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2012

Thrombin Generation Assay Is Superior to Traditional Coagulometric and Chromogenic Assays to Monitor New Oral Anticoagulants

Mullier, F., Douxfils, J., Chatelain, C., Chatelain, B. & Dogne, J-M., 2012, Blood (ASH Annual Meeting Abstracts), Nov 2012; 120: 1169.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution