Research Output 1989 2019

2019

Andexanet alfa for the reversal of factor Xa inhibitors

Favresse, J., Hardy, M., van Dievoet, M. A., Sennesael, A. L., Douxfils, J., Samama, C. M., Vornicu, O., Dincq, A. S., Lessire, S. & Mullier, F., 2019, In : Expert Opinion on Biological Therapy. 19, 5, p. 387-397 11 p.

Research output: Contribution to journalReview article

Pharmacodynamics
Hemorrhage
Phase III Clinical Trials
Factor Xa
Pharmacokinetics

Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation

Spillier, Q., Vertommen, D., Ravez, S., Marteau, R., Thémans, Q., Corbet, C., Feron, O., Wouters, J. & Frédérick, R., 1 Dec 2019, In : Scientific Reports. 9, 1, 4737.

Research output: Contribution to journalArticle

Open Access
Phosphoglycerate Dehydrogenase
Disulfiram
Alcoholism
Cysteine
Pharmaceutical Preparations

An update on laboratory assessment for direct oral anticoagulants (DOACs)

Gosselin, R. C., Adcock, D. M. & Douxfils, J., 2019, In : International Journal of Laboratory Hematology. 41 Suppl 1, p. 33-39 7 p.

Research output: Contribution to journalReview article

Anticoagulants
Pharmacodynamics
Pharmacokinetics
Antithrombins
Warfarin

Assessment of the analytical performances and sample stability on ST Genesia system using the STG-DrugScreen application

Douxfils, J., Morimont, L., Bouvy, C., de Saint-Hubert, M., Devalet, B., Devroye, C., Dincq, A-S., Dogné, J-M., Guldenpfennig, M., Baudar, J., Larock, A-S., Lessire, S. & Mullier, F., 2019, In : Journal of thrombosis and haemostasis : JTH.

Research output: Contribution to journalArticle

Thrombin
Freezing
Reference Values
Low Molecular Weight Heparin
Anticoagulants
Coagulants
Partial Thromboplastin Time
Prothrombin Time
Blood Coagulation Factors
2 Downloads (Pure)

Comparison of the impact of DOACs on hemostasis diagnostic tests

Siriez, R., Evrard, J., Dogne, J-M., Mullier, F. & Douxfils, J., 2019, Comparison of the impact of DOACs on hemostasis diagnostic tests.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

File

Determinants of the Quality of Warfarin Control after Venous Thromboembolism and Validation of the SAMe-TT2-R2 Score: An Analysis of Hokusai-VTE

Barco, S., Granziera, S., Coppens, M., Douxfils, J., Nijkeuter, M., Riva, N., Vanassche, T., Zhang, G., Lin, M., Kamphuisen, P. W., Cohen, A. T. & Beyer-Westendorf, J., 2019, In : Thrombosis and Haemostasis. 119, 4, p. 675-684 10 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
Warfarin
Quality Control
Vitamin K
Hemorrhage
Chromogenics
Plasmas
Heparin
Assays
Low Molecular Weight Heparin
infectious disease
contagious disease
land use
livestock
Disease
3 Downloads (Pure)

Estetrol is a unique native estrogen that does not modify coagulation markers in postmenopausal women and maintains sensitivity to activated protein C (APC)

Foidart, J-M., Lobo, R. A., Rosing, J., Taziaux, M., Jost, M., Douxfils, J. & Gaspard, U., 25 Sep 2019.

Research output: Contribution to conferencePoster

File

Extracellular Vesicles in Red Blood Cell Concentrates: An Overview

Wannez, A., Devalet, B., Chatelain, B., Chatelain, C., Dogné, J. M. & Mullier, F., 1 Apr 2019, In : Transfusion Medicine Reviews. 33, 2, p. 125-130 6 p.

Research output: Contribution to journalReview article

Blood
Erythrocytes
Cells
Assays
Thrombin

Growth performance and immune status in common carp Cyprinus carpio as affected by plant oil-based diets complemented with β-glucan

Nguyen, T. M., Mandiki, S. N. M., Tran, T. N. T., Larondelle, Y., Mellery, J., Mignolet, E., Cornet, V., Flamion, E. & Kestemont, P., 1 Sep 2019, In : Fish and Shellfish Immunology. 92, p. 288-299 12 p.

Research output: Contribution to journalArticle

plant fats and oils
Plant Oils
Glucans
glucans
Nutrition

Impact of betrixaban on chromogenic anti-Xa assays - Methodologies improvements

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Bouvy, C., Lessire, S., Mullier, F. & Douxfils, J., 2019, (En attente de publication).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

File

Multiscale dynamical embeddings of complex networks

Schaub, M. T., Delvenne, J. C., Lambiotte, R. & Barahona, M., 20 Jun 2019, In : Physical Review E. 99, 6, 18 p., 062308.

Research output: Contribution to journalArticle

Complex Networks
embedding
Control Theory
control theory
Vertex of a graph

Temporal Sequence of Retweets Help to Detect Influential Nodes in Social Networks

Bhowmick, A. K., Gueuning, M., Delvenne, J. C., Lambiotte, R. & Mitra, B., 1 Jun 2019, In : IEEE Transactions on Computational Social Systems. 6, 3, p. 441-455 15 p., 8692729.

Research output: Contribution to journalArticle

Social Networks
social network
Vertex of a graph
Anchors
twitter

The Anatomy of Reddit: An Overview of Academic Research

Medvedev, A. N., Lambiotte, R. & Delvenne, J. C., 1 Jan 2019, Springer Proceedings in Complexity. Springer, p. 183-204 22 p. (Springer Proceedings in Complexity).

Research output: Contribution in Book/Catalog/Report/Conference proceedingChapter

Anatomy
User Experience
Social Sciences
Social sciences
Methodology
2018

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting D-alanine-D-alanine ligase in bacterio

Ameryckx, A., Thabault, L., Pochet, L., Leimanis, S., Poupaert, J., Wouters, J., Joris, B., Van Bambeke, F. & Frederick, R., 5 Nov 2018, In : European journal of medicinal chemistry / Chimica therapeutica. 159, 5, p. 324-338 15 p.

Research output: Contribution to journalArticle

Open Access
Anti-Infective Agents
Cytotoxicity
Cells
Peptidoglycan
Structure-Activity Relationship
3 Downloads (Pure)

Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis

Spronk, H. M. H., Padro, T., Siland, J. E., Prochaska, J. H., Winters, J., van der Wal, A. C., Posthuma, J. J., Lowe, G., d'Alessandro, E., Wenzel, P., Coenen, D. M., Reitsma, P. H., Ruf, W., van Gorp, R. H., Koenen, R. R., Vajen, T., Alshaikh, N. A., Wolberg, A. S., Macrae, F. L., Asquith, N. & 43 others, Heemskerk, J., Heinzmann, A., Moorlag, M., Mackman, N., van der Meijden, P., Meijers, J. C. M., Heestermans, M., Renné, T., Dólleman, S., Chayouâ, W., Ariëns, R. A. S., Baaten, C. C., Nagy, M., Kuliopulos, A., Posma, J. J., Harrison, P., Vries, M. J., Crijns, H. J. G. M., Dudink, E. A. M. P., Buller, H. R., Henskens, Y. M. C., Själander, A., Zwaveling, S., Erküner, O., Eikelboom, J. W., Gulpen, A., Peeters, F. E. C. M., Douxfils, J., Olie, R. H., Baglin, T., Leader, A., Schotten, U., Scaf, B., van Beusekom, H. M. M., Mosnier, L. O., van der Vorm, L., Declerck, P., Visser, M., Dippel, D. W. J., Strijbis, V. J., Pertiwi, K., Ten Cate-Hoek, A. J. & Ten Cate, H., 2018, In : Thrombosis and Haemostasis. 118, 2, p. 229-250 22 p.

Research output: Contribution to journalReview article

Open Access
File
Thromboembolism
Thrombosis
Blood Platelets
Fibrin
Peptide Hydrolases

BCR-ABL Tyrosine Kinase Inhibitors: Which Mechanism(s) May Explain the Risk of Thrombosis?

Haguet, H., Douxfils, J., Chatelain, C., Graux, C., Mullier, F. & Dogne, J-M., 2018, In : TH Open. 02, 1, p. e68-e88

Research output: Contribution to journalReview article

Open Access
File
11 Downloads (Pure)
File

Betrixaban: Impact on routine and specific coagulation assays -Practical laboratory guidance

Siriez, R., Chatelain, B., Devel, P., Dogne, J-M., Douxfils, J., Mullier, F., Pochet, L., Vancraeynest, C., Gheldof, D., Evrard, J., Guldenpfennig, M. & Devroye, C., 18 Jul 2018, (Accepted/In press).

Research output: Contribution to conferencePoster

20 Downloads (Pure)
File
Hemostasis
Viper Venoms
Thrombin Time
Coagulants
Partial Thromboplastin Time

Betrixaban: Impact on routine and specific coagulation assays -Practical laboratory guidance

Siriez, R., Chatelain, B., Devel, P., Dogne, J-M., Douxfils, J., Mullier, F., Pochet, L., Vancraeynest, C., Gheldof, D., Evrard, J., Devroye, C. & Guldenpfennig, M., 10 May 2018, (Accepted/In press).

Research output: Contribution to conferencePoster

Betrixaban: Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and Practice in thrombosis and haemostasis. Issue S1 ed. Vol. Volume 2. PB364

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Betrixaban : Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, BJH - Belgian Journal of Hematology - Clinic: Abstracts - 33rd General Annual Meeting of the Belgian Hematology Society . p. 22 42 p. PP47

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Betrixaban: Impact on routine and specific coagulation assays - Practical laboratory guidance

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, International Society for Laboratory Hematology: Abstracts.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access
Lymphoma, Large B-Cell, Diffuse
MicroRNAs
Longitudinal Studies
Biomarkers
Clinical Studies

Clot waveform analysis: Determination of optimal wavelength to assess the fibrin coagulation process

Evrard, J., Siriez, R., Bouvy, C., Laloy, J., Mullier, F., Dogne, J-M. & Douxfils, J., 5 Jul 2018, JTH-Journal of Thrombosis and haemostasis: Research and practice of thrombosis and haemostasis. issue S1 ed. Vol. 2. PB385

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Clot waveform analysis for measuring and quantifying fibrin clot formation

Evrard, J., Siriez, R., Themans, P., Laloy, J., Mullier, F., Dogne, J-M. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and pratice in thrombosis and haemostasis. issue S1 ed. Vol. 2. PB582

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Constraints from microlensing experiments on clustered primordial black holes

García-Bellido, J. & Clesse, S., 1 Mar 2018, In : Physics of the Dark Universe. 19, p. 144-148 5 p.

Research output: Contribution to journalArticle

experiment
dark matter
mass distribution
anisotropy
power spectra
Thromboxane B2
Liquid chromatography
Platelets
Tandem Mass Spectrometry
Liquid Chromatography

Enhancing action of positive allosteric modulators through the design of dimeric compounds

Drapier, T., Geubelle, P., Bouckaert, C., Nielsen, L., Laulumaa, S., Goffin, E., Dilly, S., Francotte, P., Hanson, J., Pochet, L., Kastrup, J. S. & Pirotte, B., 28 Jun 2018, In : Journal of Medicinal Chemistry. 61, 12, p. 5279-5291 13 p.

Research output: Contribution to journalArticle

Benzothiadiazines
Ligands
Ethane
AMPA Receptors
HEK293 Cells

EudraVigilance Medicines Safety Database: Publicly Accessible Data for Research and Public Health Protection

Postigo, R., Brosch, S., Slattery, J., van Haren, A., Dogné, J. M., Kurz, X., Candore, G., Domergue, F. & Arlett, P., 1 Jul 2018, In : Drug Safety. 41, 7, p. 665-675 11 p.

Research output: Contribution to journalArticle

Open Access
Public health
Medicine
Pharmacovigilance
Public Health
Databases

Evaluation of the DOAC-Stop® Procedure to Overcome the Effect of DOACs on Several Thrombophilia Screening Tests

Favresse, J., Lardinois, B., Sabor, L., Devalet, B., Vandepapeliere, J., Braibant, M., Lessire, S., Chatelain, B., Jacqmin, H., Douxfils, J. & Mullier, F., 2018, In : TH Open. 2, 2, p. e202-e209

Research output: Contribution to journalArticle

Thrombophilia
Anticoagulants
Lupus Coagulation Inhibitor
Prothrombin Time
Antithrombin Proteins

International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants

Gosselin, R. C., Adcock, D. M., Bates, S. M., Douxfils, J., Favaloro, E. J., Gouin-Thibault, I., Guillermo, C., Kawai, Y., Lindhoff-Last, E. & Kitchen, S., 1 Mar 2018, In : Thrombosis and Haemostasis. 118, 3, p. 437-450 14 p.

Research output: Contribution to journalArticle

Open Access
Hematology
Anticoagulants
Point-of-Care Systems
Partial Thromboplastin Time
Prothrombin Time
5 Downloads (Pure)

In Vitro Effects of BCR-ABL Tyrosine Kinase Inhibitors on Endothelial Cells Survival and Functions

Haguet, H., Douxfils, J., Chatelain, C., GRAUX, C., Mullier, F. & Dogne, J-M., 5 Jul 2018, Special Issue: Abstracts of the 64th Annual Meeting of the Scientific Standardization Committee of the International Society on Thrombosis and Haemostasis, July 18–21, 2018. p. 242 1 p. PB497. (Research and Practice in Thrombosis and Haemostasis; vol. 2, no. S1).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access
File
Protein-Tyrosine Kinases
Cell Survival
Endothelial Cells
E-Selectin
Vascular Cell Adhesion Molecule-1

In Vitro Effects of BCR-ABL Tyrosine Kinase Inhibitors on Endothelial Cells Survival and Functions

Haguet, H., Douxfils, J., Chatelain, C., GRAUX, C., Mullier, F. & Dogne, J-M., 19 Jul 2018.

Research output: Contribution to conferencePoster