Faculty of Medicine

  • 5000

    Belgium

Research Output 1970 2019

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Review article
2019

Andexanet alfa for the reversal of factor Xa inhibitors

Favresse, J., Hardy, M., van Dievoet, M. A., Sennesael, A. L., Douxfils, J., Samama, C. M., Vornicu, O., Dincq, A. S., Lessire, S. & Mullier, F., 2019, In : Expert Opinion on Biological Therapy. 19, 5, p. 387-397 11 p.

Research output: Contribution to journalReview article

Pharmacodynamics
Hemorrhage
Phase III Clinical Trials
Factor Xa
Pharmacokinetics

An update on laboratory assessment for direct oral anticoagulants (DOACs)

Gosselin, R. C., Adcock, D. M. & Douxfils, J., 2019, In : International Journal of Laboratory Hematology. 41 Suppl 1, p. 33-39 7 p.

Research output: Contribution to journalReview article

Anticoagulants
Pharmacodynamics
Pharmacokinetics
Antithrombins
Warfarin

Extracellular Vesicles in Red Blood Cell Concentrates: An Overview

Wannez, A., Devalet, B., Chatelain, B., Chatelain, C., Dogné, J. M. & Mullier, F., 1 Apr 2019, In : Transfusion Medicine Reviews. 33, 2, p. 125-130 6 p.

Research output: Contribution to journalReview article

Blood
Erythrocytes
Cells
Assays
Thrombin
2018

BCR-ABL Tyrosine Kinase Inhibitors: Which Mechanism(s) May Explain the Risk of Thrombosis?

Haguet, H., Douxfils, J., Chatelain, C., Graux, C., Mullier, F. & Dogne, J-M., 2018, In : TH Open. 02, 1, p. e68-e88

Research output: Contribution to journalReview article

Open Access
File
3 Downloads (Pure)

In vitro models of dermatophyte infection to investigate epidermal barrier alterations

Faway, É., Lambert De Rouvroit, C. & Poumay, Y., 28 Aug 2018, In : Experimental dermatology. 27, 8, p. 915-922 8 p.

Research output: Contribution to journalReview article

Arthrodermataceae
Tinea
Skin
Animals
Infection

Launching Global Lung Function Initiative reference values in Belgium: tips and tricks

Derom, E., Liistro, G., Oostveen, E., Marchand, É., Bedert, L., Peché, R. & Janssens, W., 1 Aug 2018, In : European respiratory journal. 52, 2, 3 p., 1800922.

Research output: Contribution to journalReview article

1 Downloads (Pure)

Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice

Cataldo, D., Derom, E., Liistro, G., Marchand, É., Ninane, V., Peché, R., Slabbynck, H., Vincken, W. & Janssens, W., 2018, In : International Journal of COPD. 13, p. 2089-2099 11 p.

Research output: Contribution to journalReview article

Open Access
File
Chronic Obstructive Pulmonary Disease
Adrenal Cortex Hormones
Primary Care Physicians
Marketing
Habits

Therapeutic applications of prostaglandins and thromboxane A 2 inhibitors in abdominal aortic aneurysms

Courtois, A., Makrygiannis, G., Cheramy-Bien, J. P., Purnelle, A., Pirotte, B., Dogné, J. M., Hanson, J., Defraigne, J. O., Drion, P. & Sakalihasan, N., 1 Jan 2018, In : Current Drug Targets. 19, 11, p. 1247-1255 9 p.

Research output: Contribution to journalReview article

Thromboxanes
Abdominal Aortic Aneurysm
varespladib methyl
Prostaglandins
Thromboxane A2
2017
13 Downloads (Pure)

Calcitonin: Survey of new anatomy data to pathology and therapeutic aspects

Faour, O. & Gilloteaux, J., 1 Mar 2017, In : Translational Research in Anatomy. 6, p. 4-15 12 p.

Research output: Contribution to journalReview article

Open Access
File
Calcitonin
Anatomy
Pathology
Thyroid Gland
Therapeutics

Clinical pearls: Laboratory assessments of direct oral anticoagulants (DOACS)

Gosselin, R., Douxfils, J. & Adcock, D., 2017, In : Hamostaseologie. 37, 4, p. 295-301 7 p.

Research output: Contribution to journalReview article

Anticoagulants
Factor Xa
Venous Thromboembolism
Thrombin
Atrial Fibrillation

Functional assays in the diagnosis of heparin-induced thrombocytopenia: A review

Minet, V., Dogné, J. M. & Mullier, F., 1 Apr 2017, In : Molecules. 22, 4, 617.

Research output: Contribution to journalReview article

heparins
platelets
Thrombocytopenia
Heparin
Assays

Non-vitamin-Koral anticoagulants and laboratory testing: Now and in the future: Views from a workshop at the European Medicines Agency (EMA)

Salmonson, T., Dogne, J. M., Janssen, H., Burgos, J. G. & Blake, P., 1 Jan 2017, In : European Heart Journal - Cardiovascular Pharmacotherapy. 3, 1, p. 42-47 6 p.

Research output: Contribution to journalReview article

Open Access
Anticoagulants
Education
Vitamin K
Kidney
Therapeutics

Off-label use of vaccines

Neels, P., Southern, J., Abramson, J., Duclos, P., Hombach, J., Marti, M., Fitzgerald-Husek, A., Fournier-Caruana, J. & Hanquet, G., 25 Apr 2017, In : Vaccine. 35, 18, p. 2329-2337 9 p.

Research output: Contribution to journalReview article

Off-Label Use
Vaccines
vaccines
public health
Public Health
Open Access
lysosomes
Endosomes
Hydrolases
Lysosomes
classifying
2016

Facing coagulation disorders after acute trauma

Mullier, F., Lessire, S., De Schoutheete, J. C., Chatelain, B., Deneys, V., Mathieux, V., Hachimi Idrissi, S., Dogne, J. M., Watelet, J. B., Gourdin, M. & Dincq, A. S., 1 Jan 2016, In : B-ENT. 12, 1, p. 67-85 19 p.

Research output: Contribution to journalReview article

Open Access
File
bleeding
coagulation
Coagulation
Hypothermia
disorders
4 Downloads (Pure)

Minimisation of bleeding risks due to direct oral anticoagulants

Vornicu, O., Larock, A. S., Douxfils, J., Mullier, F., Dubois, V., Dogne, J. M., Gourdin, M., Lessire, S. & Dincq, A. S., 2016, In : European Medical Journal Hematology. 4, 1, p. 78-90 13 p.

Research output: Contribution to journalReview article

Open Access
File
Anticoagulants
Hemorrhage
Antidotes
Physicians
Patient Selection

Modes of internalizations of human prostate carcinoma (DU145) cells in vitro and in murine xenotransplants

Gilloteaux, J., Ruffo, C., Jamison, J. M. & Summers, J. L., Feb 2016, In : Ultrastructural Pathology. 40, 5, p. 231-239 9 p.

Research output: Contribution to journalReview article

Prostate
Carcinoma
Entosis
Reactive Oxygen Species
Cytophagocytosis
29 Downloads (Pure)
Open Access
File
Pharmacovigilance
Patient Participation
Telemedicine
Drug-Related Side Effects and Adverse Reactions
Internet
2015

Anticoagulants directs oraux: Actualités pour les biologistes

Mullier, F., Douxfils, J., Tamigniau, A., Dogné, J. M., Horellou, M. H., Flaujac, C., Chatelain, B., Goffinet, C., Samama, M. M. & Gouin-Thibault, I., 1 May 2015, In : Annales de biologie clinique. 73, 3, p. 333-344 12 p.

Research output: Contribution to journalReview article

Anticoagulants
Drug interactions
Monitoring
Warfarin
Coagulation
Anticoagulants
Plasmas
Drug interactions
Pharmaceutical Preparations
Surgery
2014
60 Downloads (Pure)

Les mirages des nouveaux anticoagulants oraux.

Larock, A. S., Mullier, F., Laloux, P., Douxfils, J., Dogné, J. M. & Spinewine, A., 2014, In : Journal de Pharmacie de Belgique. 1, p. 38-41 4 p.

Research output: Contribution to journalReview article

Open Access
File
43 Downloads (Pure)
File
Anticoagulants
Surgery
Pharmacodynamics
Hemorrhage
Antidotes
47 Downloads (Pure)

Measurement of non-VKA oral anticoagulants versus classic ones: The appropriate use of hemostasis assays

Douxfils, J., Tamigniau, A., Chatelain, B., Goffinet, C., Dogné, J. M. & Mullier, F., 4 Nov 2014, In : Thrombosis journal. 12, 24, p. 1-18 18 p.

Research output: Contribution to journalReview article

Open Access
File
Hemostasis
Anticoagulants
Vitamin K
Heparin
Low Molecular Weight Heparin
62 Downloads (Pure)

Pourquoi, quand et comment doser les nouveaux anticoagulants oraux?

Tamigniau, A., Douxfils, J., Nicolas, J. B., Devalet, B., Larock, A. S., Spinewine, A., Dincq, A. S., Lessire, S., Gourdin, M., Watelet, J. B., Mathieux, V., Chatelain, C., Dogné, J. M., Chatelain, B. & Mullier, F., 5 Feb 2014, In : Revue médicale suisse. 10, 416, p. 326-333 8 p.

Research output: Contribution to journalReview article

File
Anticoagulants
Vitamin K
Acute Kidney Injury
Pharmacokinetics
Therapeutics
39 Downloads (Pure)

Preventive strategies against bleeding due to nonvitamin K antagonist oral anticoagulants

Lessire, S., Dincq, A. S., Douxfils, J., Devalet, B., Nicolas, J. B., Spinewine, A., Larock, A. S., Dogné, J. M., Gourdin, M. & Mullier, F., 2014, In : BioMed research international. 2014, 616405.

Research output: Contribution to journalReview article

Open Access
File
Anticoagulants
Hemorrhage
Warfarin
Enoxaparin
Antidotes

Suivi biologique des patients sous nouveaux anticoagulants oraux: qui, quand, comment ?

Mullier, F., Douxfils, J., Tamigniau, A., Dogne, J-M., Horellou, M-H., Flaujac, C., Chatelain, B., Samama, M. M. & Gouin-Thibault, I., 2014, In : Feuillets de Biologie. 55, 319, p. 5-14

Research output: Contribution to journalReview article

Open Access
File
Paroxysmal Hemoglobinuria
Thrombosis
Platelet Activation
Hematopoietic Stem Cells
Hemolysis
2013
808 Downloads (Pure)

Rivaroxaban (Xarelto®): Guide de la pratique officinale

Douxfils, J., Michel, S., Beauloye, C., Goethals, M., Hainaut, P., Heidbuchel, H., Hermans, C., Ickx, B., Jochmans, K., Mottes, S., Mullier, F., Peeters, A., Scavée, C., Sinnaeve, P., Sprynger, M., Thijs, V., Vandenbroeck, C., Vandermeulen, E., Verhamme, P. & Dogné, J. M., 1 Mar 2013, In : Journal de Pharmacie de Belgique. 1, p. 28-36 9 p.

Research output: Contribution to journalReview article

Open Access
File
Pharmacists
Anticoagulants
Food-Drug Interactions
Vitamin K
Environmental Monitoring
2012

Dabigatran bij voorkamerfibrillatie: Klinische studies, voordelen en beperkingen

Sternotte, A., Douxfils, J., Mullier, F., Dogné, J-M., Chatelain, B., Chatelain, C., Spinewine, A. & Douxfils, J., 1 Mar 2012, In : Farmaceutisch Tijdschrift voor Belgie. 89, 1, p. 8-17 10 p.

Research output: Contribution to journalReview article

Atrial Fibrillation
Stroke
Antithrombins
Vitamin K
Drug Monitoring
92 Downloads (Pure)

Dabigatran dans la fibrillation auriculaire: Études cliniques, intérêts et limites

Sternotte, A., Douxfils, J., Mullier, F., Dogné, J-M., Chatelain, B., Chatelain, C. & Spinewine, A., Mar 2012, In : Journal de Pharmacie de Belgique. 67, 1, p. 8-17 10 p.

Research output: Contribution to journalReview article

Open Access
File
Atrial Fibrillation
Stroke
Antithrombins
Vitamin K
Drug Monitoring
2007

Dual carbonic anhydrates - Cyclooxygenase-2 inhibitors

Dogné, J. M., Thiry, A., Practico, D., Masereel, B. & Supuran, C. T., 1 May 2007, In : Current Topics in Medicinal Chemistry. 7, 9, p. 885-891 7 p.

Research output: Contribution to journalReview article

Celecoxib
Cyclooxygenase 2 Inhibitors
Sulfonamides
Carbonic Anhydrase II
Carbonic Anhydrases
2004

New developments on thromboxane and prostacyclin modulators part 1: Prostacyclin modulators

de Leval, X., Hanson, J., David, J. L., Masereel, B., Pirotte, B. & Dogné, J. M., 1 May 2004, In : Current Medicinal Chemistry. 11, 10, p. 1243-1252 10 p.

Research output: Contribution to journalReview article

Thromboxanes
Epoprostenol
Modulators
Thromboxane A2
Cardiovascular System
2003

Recent developments in 5-lipoxygenase inhibitors

Julémont, F., Dogné, J. M., Laeckmann, D., Pirotte, B. & de Leval, X., 1 Jan 2003, In : Expert Opinion on Therapeutic Patents. 13, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

Arachidonate 5-Lipoxygenase
Lipoxygenase Inhibitors
Patents
Leukotrienes
Lipoxygenases
2002

Potential therapeutic application of the association of vitamins C and K3 in cancer treatment

Buc Calderon, P., Cadrobbi, J., Marques, C., Hong-Ngoc, N., Jamison, J. M., Gilloteaux, J., Summers, J. L. & Taper, H. S., 2002, In : Current Medicinal Chemistry. 9, 24, p. 2271-2285 15 p.

Research output: Contribution to journalReview article

Vitamin K 3
Oncology
Ascorbic Acid
Tumors
Cell death