Faculty of Medicine

  • 5000

    Belgium

Research Output 1970 2019

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Literature review
2016

Toward a Better Understanding of the Complexity of Cancer Drug Resistance

Gottesman, M. M., Lavi, O., Hall, M. D. & Gillet, J. P., 6 Jan 2016, In : Annual Review of Pharmacology and Toxicology. 56, p. 85-102 18 p.

Research output: Contribution to journalLiterature review

Drug Resistance
Pharmaceutical Preparations
Tumors
Neoplasms
Cells
2013

The clinical relevance of cancer cell lines

Gillet, J-P., Varma, S. & Gottesman, M. M., 3 Apr 2013, In : Journal of the National Cancer Institute. 105, 7, p. 452-458 7 p.

Research output: Contribution to journalLiterature review

Cell Line
Neoplasms
Translational Medical Research
Genomics
Technology
2012

Drug resistance: Still a daunting challenge to the successful treatment of AML

Shaffer, B. C., Gillet, J-P., Patel, C., Baer, M. R., Bates, S. E. & Gottesman, M. M., 1 Feb 2012, In : Drug Resistance Updates. 15, 1-2, p. 62-69 8 p.

Research output: Contribution to journalLiterature review

Drug Resistance
Acute Myeloid Leukemia
Drug Therapy
Clinical Trials
Myeloid Progenitor Cells

Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

Dolušić, E., Larrieu, P., Moineaux, L., Stroobant, V., Pilotte, L., Colaux, D., Van den Eynde, B., Masereel, B., Wouters, J. & Frédérick, R., 2012, In : ChemMedChem. p. 371 1 p.

Research output: Contribution to journalLiterature review

2010

Discovery and optimization of indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2-3 dioxygenase (IDO), a promising target for anti-cancer immunotherapy.

Frédérick, R., Blanc, S., Larrieu, P., Moineaux, L., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colaux, D., Wouters, J., Masereel, B., Van den Eynde, B. & Dolušić, E., 2010, In : Drugs of the future. 35, suppl A, p. 181-182

Research output: Contribution to journalLiterature review

Implication of tissue-factor bearing microparticles in thrombosis associated with breast cancer

Mullier, F., Gheldof, D., Robert, S., Bailly, N., Devel, P., Michiels, C., Doyen, C., Christian, C., Chatelain, B. & Dogné, J-M., 2010, In : Belgian Society of Clinical Biology, Anvers, October 16th; 2010.

Research output: Contribution to journalLiterature review

Inhibition study of monoamine oxidases by ß-carboline derivatives.

Reniers, J., Robert, S., Frédérick, R., Masereel, B., Vincent, S. & Wouters, J., 2010, In : Drugs of the future. 35, suppl A, p. 189

Research output: Contribution to journalLiterature review

Platelet Microparticle Generation Assay: a valuable and simpler alternative to 14C-SRA for type-II HIT diagnosis.

Mullier, F., Bailly, N., Cornet, Y., Robert, S., Osselaer, J-C., Chatelain, C., Elalamy, I., Dogné, J-M. & Chatelain, B., 2010, In : Belgian Society of Clinical Biology, Anvers, October 16th; 2010.

Research output: Contribution to journalLiterature review

Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

Moineaux, L., Charlier, C., Dolušić, E., Larrieu, P., Pilotte, L., Colaux, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, In : Drugs of the future. 35, suppl A, p. 189

Research output: Contribution to journalLiterature review

The tick protein Ir-CPI efficiently delays contact pathway induced thrombin generation and displays in vivo antithrombotic activity

Robert, S., Decrem, Y., Rath, G., Dessy, C., Feron, O., Mullier, F., Devel, P., Chatelain, B., Dogné, J-M. & Godfroid, E., 2010, In : 49) NARILIS symposium. Faculté de Médecine. FUNDP Namur. October 23th, 2010.

Research output: Contribution to journalLiterature review

2009

Accurate quantification of microparticles by flow cytometry: important issues.

Mullier, F., Dogné, J-M., Bailly, N., Cornet, Y., Robert, S. & Chatelain, B., 2009, In : Journal of Thrombosis and Haemostasis. 7, 2

Research output: Contribution to journalLiterature review

A novel concept to improve diagnosis of Hereditary Spherocytosis.

Mullier, F., Bailly, N., Cornet, Y., Dogné, J-M. & Chatelain, B., 2009, In : Abstract Book-Société Belge Biologie Clinique 2009.

Research output: Contribution to journalLiterature review

2008

Biotin tagged beta-cyclodextrin: a potential new drug targeting system for tumor therapy

Bertolla, C., Pochet, L. & Masereel, B., 2008, In : Drugs of the future. 33, suppl. A

Research output: Contribution to journalLiterature review

Microwave assisted medicinal chemistry : application to the synthesis of coumarins and cyclodextrins

Bertolla, C., Robert, S., Pochet, L. & Masereel, B., 2008, In : Chimie nouvelle. 98, p. 25-25 1 p.

Research output: Contribution to journalLiterature review

Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors

Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2008, In : Drugs of the future. 33, suppl A

Research output: Contribution to journalLiterature review

2007

Chemotherapy-induced resistance by ATP-binding cassette transporter genes

Gillet, J-P., Efferth, T. & Remacle, J., 2007, In : Biochimica Biophysica Acta. . 1775, 2, p. 237-62 26 p.

Research output: Contribution to journalLiterature review

ATP-Binding Cassette Transporters
Drug Therapy
Genes
Multiple Drug Resistance
Pharmaceutical Preparations

Thrombin activity profile: a powerful ex vivo screening test for the development of anticoagulant drugs

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, In : Journal of Thrombosis and Haemostasis. 5, Suppl. 2

Research output: Contribution to journalLiterature review

2006
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DualChip® microarray as a new tool in cancer research

Gillet, J-P., De Longueville, F. & Remacle, J., 1 Jan 2006, In : Expert Review of Molecular Diagnostics. 6, 3, p. 295-306 12 p.

Research output: Contribution to journalLiterature review

Oligonucleotide Array Sequence Analysis
Research
Neoplasms
Gene Expression Profiling
Drug Resistance

Indanesulfonamides as carbonic anhydrase inhibitors

Thiry, A., Ledecq, M., Cecchi, A., Dogné, J-M., Wouters, J., Supuran, C. T. & Masereel, B., 2006, In : Drugs of the future. 31, A

Research output: Contribution to journalLiterature review

2005

BM-573, a thromboxane A2 modulator, fails to prevent reperfusion injury in acutely ischemic pigs

Kolh, P., Rolin, S., Sato, V., Petein, M., Ghuysen, A., Lambermont, B., Masereel, B., D'Orio, V., Limet, R. & Dogne, JM., 2005, In : Journal of Molecular and Cellular Cardiology . 39, p. 1035 1 p.

Research output: Contribution to journalLiterature review

2004

Characterization of preferential activity on platelet thromboxane A2 receptors of BM-613, a new thromboxane A2 antagonist

Hanson, J., Rolin, S., De Leval, X., Neven, P., Masereel, B., Pirotte, B. & Dogné, J-M., 2004, In : Fundamental and Clinical Pharmacology.

Research output: Contribution to journalLiterature review

Coumarins as serine protease inhibitors

Pochet, L., Frédérick, R., Robert, S., Rolin, S. & Masereel, B., 2004, In : Drugs of the future. 29, A

Research output: Contribution to journalLiterature review

In vivo pharmacological evaluation of BM-573, an original thromboxane A2 receptor antagonist and thromboxane synthase inhibitor.

Hanson, J., Kolh, P., Rolin, S., Tchana-Sato, V., De Leval, X., Petein, M., Masereel, B., Pirotte, B., Dogné, J-M. & Lambermont, B., 2004, In : Fundamental and Clinical Pharmacology.

Research output: Contribution to journalLiterature review

Synthesis and pharmacological evaluation of original thromboxane A2 receptor antagonists derived from BM-573.

Hanson, J., Renard, J-F., Rolin, S., Neven, P., de Leval, X., Dogné, J-M., Dogné, J-M. & Pirotte, B., 2004, In : Fundamental and Clinical Pharmacology. 18, p. 593-599 7 p.

Research output: Contribution to journalLiterature review

2003

A dual thromboxane inhibitor and thromboxane receptor antagonist prevents pig myocardial infarction induced by coronary thrombosis

Rolin, S., Pétein, M., Tchana-Sato, V., Dogné, J-M., Lambermont, B., Ghuysen, A., Kolh, P. & Masereel, B., 2003, In : Basic Research in Cardiology. 98

Research output: Contribution to journalLiterature review

A dual thromboxane inhibitor and thromboxane receptor antagonist prevents pig myocardial infarction induced by coronary thrombosis

Rolin, S., Petein, M., Tchana-Sato, V., Dogné, J-M., Lambermont, B., Ghuysen, A., Kolh, P. & Masereel, B., 2003, In : European Heart Journal. 24, Suppl. S

Research output: Contribution to journalLiterature review

Antithrombotic activity of BM-573, a novel thromboxane modulator, in rat arterial thrombosis model, pig myocardial infarction model and its effects on bleeding time

Dogné, J-M., Kolh, P., Rolin, S., Tchana-Sato, V., Hanson, J., de Leval, X., Lambermont, B., Ghuysen, A., Pétein, M., de Leval, L., Masereel, B. & Pirotte, B., 2003, In : Blood. November suppl, p. 4213

Research output: Contribution to journalLiterature review

BM-613, a new thromboxane A2 antagonist, is characterized by a preferential activity on platelet thromboxane a2 receptors

Hanson, J., Rolin, S., de Leval, X., Neven, P., de Leval, L., Masereel, B., Pirotte, B. & Dogné, J-M., 2003, In : Blood. November suppl, n°3013

Research output: Contribution to journalLiterature review

Haemodynamic effect of thromboxane A2 inhibition in acute pulmonary embolism

Ghuysen, A., Lambermont, B., Kolh, P., Morimont, B., Tchana-Sato, V., Dogné, J-M., Rolin, S. & D'Orio, V., 2003, In : European Journal of Heart Failure. 2, 1

Research output: Contribution to journalLiterature review

2002

Anti-platelet and antithrombotic properties of the nitrobenzenic sulfonylurea BM-573

Dogné, J-M., Benoit, P., de Leval, X., Rolin, S., Neven, P., Kolh, P., Masereel, B. & David, J-L., 2002, In : Fundamental and Clinical Pharmacology. 16, p. 245

Research output: Contribution to journalLiterature review

Antithrombotic properties of BM-573 an original dual thromboxane receptor antagonist and thromboxane synthase inhibitor

Dogné, J-M., Benoit, P., de Leval, X., Rolin, S., Kolh, P., Ghysen, A., Tchana-Sato, V. & Masereel, B., 2002, In : Pathophysiology of Haemostasis and Thrombosis. 32, (S2), p. 60

Research output: Contribution to journalLiterature review

2001

Design and pharmacological evaluation of an original non-carboxylic thromboxane receptor antagonist and thromboxane synthase inhibitor as promising antiplatelet agent

Dogné, J-M., de Leval, X., Rolin, S., Neven, P., Kolh, P., David, J-L., Delarge, J. & Masereel, B., 2001, In : Thrombosis and Haemostasis. July suppl, p. P1630

Research output: Contribution to journalLiterature review

Pharmacological evaluation of BM-573 an original dual thromboxane receptor antagonist and thromboxane synthase inhibitor as novel potent antithrombotic agent

Dogné, J-M., de Leval, X., Benoit, P., Neven, P., de Leval, L., Rolin, S., David, J-L. & Masereel, B., 2001, In : Blood. december, suppl

Research output: Contribution to journalLiterature review

Pharmacological evaluation of original sulfonylureas as thromboxane A2 antagonists

Dogné, J-M., de Leval, X., Neven, P., Somers, F., Delarge, J., Rolin, S., Michaux, C., Wouters, J., Pirotte, B., Damas, J. & Masereel, B., 2001, In : Fundamental and Clinical Pharmacology. 300

Research output: Contribution to journalLiterature review

2000

BM-144, a novel thromboxane A2 receptor antagonist relaxes trachea guinea pig in vitro

de Leval, X., Delarge, J., Rolin, S., Masereel, B. & Dogne, J-M., 2000, In : Journal of Allergy and Clinical Immunology. 105, 1, p. S21

Research output: Contribution to journalLiterature review

Characterization of the antiplatelet activity of ticlopidine and acetylsalicylic acid by PFA-100

Dogné, J-M., de Leval, X., Neven, P., Rolin, S., David, J-L., Delarge, J. & Masereel, B., 2000, In : Fundamental and Clinical Pharmacology. 14, p. 168

Research output: Contribution to journalLiterature review

Design, synthesis and pharmacological evalution of original thromboxane receptor antagonists.

Dogné, J-M., de Leval, X., Delarge, J., Reginster, J-Y., Henrottin, Y., Neven, P., Rolin, S. & Masereel, B., 2000, In : Mediators of Inflammation. 9, p. 53

Research output: Contribution to journalLiterature review

Design and pharmacological evaluation of a novel combined thromboxane A2 receptor antagonist and thromboxane synthase inhibitor derived from torasemide as promising antiplatelet agent

Dogné, J-M., de Leval, X., Rolin, S., Neven, P., Kolh, P., David, J-L., Fillet, G., Delarge, J. & Masereel, B., 2000, In : Blood. 96, 11, p. 230

Research output: Contribution to journalLiterature review

Development of pepsin and three pancreatic enzymes in Perca fluviatilis larvae.

CUVIER-PERES, A. & Kestemont, P., 2000, In : aquaculture in the new millenium, EAS spec. publ.. 28

Research output: Contribution to journalLiterature review

Effects of TXA2 receptor antagonists derived from torasemide on platelet function

Dogné, J-M., de Leval, X., Neven, P., Rolin, S., Somers, F., David, J-L., Delarge, J. & Masereel, B., 2000, In : Fundamental and Clinical Pharmacology. 14, p. 168

Research output: Contribution to journalLiterature review