Access to Care and Therapeutic Optimisation

Research output

Research output per year 1997 2021

• 637 Citations
• 16 h-Index
• 64 Poster
• 59 Article
• 15 Conference contribution
• 12 Commissioned report
• 47 More
  • 7 Chapter
  • 6 Review article
  • 6 Other contribution
  • 5 Book
  • 4 Other report
  • 3 Chapter (peer-reviewed)
  • 2 Meeting abstract
  • 2 Short survey
  • 2 Patent
  • 1 Foreword/postscript
  • 1 Abstract
  • 1 Paper
  • 1 Book/Film/Article review
  • 1 Editorial
  • 1 Letter
  • 1 Special issue
  • 1 Featured article
  • 1 Web publication/site
  • 1 Master's Thesis

Research output per year

Research output per year

Search results

• 2021

  Comprehensive review of the impact of direct oral anticoagulants on thrombophilia diagnostic tests: Practical recommendations for the laboratory

  SIRIEZ, ROMAIN., DOGNE, J-M., Gosselin, R. C., Laloy, J., MULLIER, F. & Douxfils, J., Feb 2021, In: International Journal of Laboratory Hematology. 43, 1, p. 7-20 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Thrombophilia
  • Routine Diagnostic Tests
  • Anticoagulants
  • Protein C
  • Dabigatran

• Des pistes pour réconcilier bien-être et performance existent!

  Lo Giudice, C. (ed.) & Flohimont, V., 6 Jan 2021, HR Square, 38, p. 34-35.

  Research output: Contribution to specialist publication › Article

• 2020

  À quoi ressemblera le travail à distance dans le monde post-covid-19?

  Lo Giudice, C. (ed.), Flohimont, V. & Pelletier, M-C., Jul 2020, HR Square, 35.

  Research output: Contribution to specialist publication › Article

• Endothelial Glycocalyx Impairment in Disease: Focus on Hyaluronan Shedding

  Dogne, S. & Flamion, B., 1 Apr 2020, In: The American Journal of Pathology. 190, 4, p. 768-780 13 p., PMID: 32035885.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycocalyx
  • Hyaluronic Acid
  • Permeability
  • Syndecan-1
  • Endothelial Cells

• Importance of measuring pharmacologically active metabolites of edoxaban: development and validation of an ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method

  Siriez, R., Alpan, L., Elasaad, K., Devel, P., Laloy, J., Dogne, J-M. & Douxfils, J., 1 Apr 2020, In: Journal of Thrombosis and Thrombolysis. 49, 3, p. 395-403 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • edoxaban
  • Tandem Mass Spectrometry
  • High Pressure Liquid Chromatography
  • Drug Interactions
  • Factor Xa Inhibitors
  7 Downloads (Pure)

• Validation and standardization of the ETP-based activated protein C resistance test for the clinical investigation of steroid contraceptives in women: an unmet clinical and regulatory need

  Douxfils, J., Morimont, L., Delvigne, A-S., Devel, P., Masereel, B., Haguet, H., Bouvy, C. & Dogné, J-M., 28 Jan 2020, In: Clinical Chemistry and Laboratory Medicine. 58, 2, p. 294-305 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Activated Protein C Resistance
  • Assays
  • Protein C
  • Contraceptive Agents
  • Thrombin
• 2019

  Assessment of the analytical performances and sample stability on ST Genesia system using the STG-DrugScreen application

  Douxfils, J., Morimont, L., Bouvy, C., de Saint-Hubert, M., Devalet, B., Devroye, C., Dincq, A-S., Dogné, J-M., Guldenpfennig, M., Baudar, J., Larock, A-S., Lessire, S. & Mullier, F., Aug 2019, In: Journal of thrombosis and haemostasis : JTH. 17, 8, p. 1273-1287 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Thrombin
  • Freezing
  • Reference Values
  • Low Molecular Weight Heparin
  • Anticoagulants
  1 Downloads (Pure)

• Development of new methodologies for the chromogenic estimation of betrixaban concentrations in plasma

  Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Bouvy, C., Lessire, S., Mullier, F. & Douxfils, J., 1 Apr 2019, In: International Journal of Laboratory Hematology. 41, 2, p. 250-261 12 p.

  Research output: Contribution to journal › Article › peer-review

  • betrixaban
  • Chromogenics
  • Plasmas
  • Factor Xa Inhibitors
  • Assays

• Platelet hyaluronidase-2 regulates the early stages of inflammatory disease in colitis

  Petrey, A. C., Obery, D. R., Kessler, S. P., Zawerton, A., Flamion, B. & de la Motte, C. A., 29 Aug 2019, In: Blood. 134, 9, p. 765-775 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Platelets
  • Hyaluronoglucosaminidase
  • Colitis
  • Blood Platelets
  • Hyaluronic Acid
  3 Downloads (Pure)
• 2018

  Allocations familiales, familles recomposées et transfert de compétences : note sous Cour constitutionnelle, 12 octobre 2017

  Flohimont, V., 2018, In: Revue trimestrielle de Droit familial. 2018, 1, p. 199-213

  Research output: Contribution to journal › Article › peer-review

• Betrixaban: Impact on Routine and Specific Coagulation Assays-A Practical Laboratory Guide

  Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Mullier, F. & Douxfils, J., 1 Jul 2018, In: Thrombosis and Haemostasis. 118, 7, p. 1203-1214 12 p.

  Research output: Contribution to journal › Article › peer-review

  File

  • betrixaban
  • Viper Venoms
  • Hemostasis
  • Factor Xa Inhibitors
  • Thrombin Time
  89 Downloads (Pure)

• Endothelial Glycocalyx as a Shield Against Diabetic Vascular Complications: Involvement of Hyaluronan and Hyaluronidases

  Dogne, S., Flamion, B. & Caron, N., 1 Jul 2018, In: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 38, 7, p. 1427-1439 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycocalyx
  • Diabetic Angiopathies
  • Hyaluronoglucosaminidase
  • Hyaluronic Acid
  • Syndecans

• EudraVigilance Medicines Safety Database: Publicly Accessible Data for Research and Public Health Protection

  Postigo, R., Brosch, S., Slattery, J., van Haren, A., Dogné, J. M., Kurz, X., Candore, G., Domergue, F. & Arlett, P., 1 Jul 2018, In: Drug Safety. 41, 7, p. 665-675 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Public health
  • Medicine
  • Pharmacovigilance
  • Public Health
  • Databases

• Note sous Cass. (3e ch. F), 19 juin 2017, S.16.0006.F

  Flohimont, V., 2018, In: Revue trimestrielle de Droit familial. 1, p. 217-219

  Research output: Contribution to journal › Article

  Open Access

  File
  1 Downloads (Pure)

• Note sous Cour constitutionnelle, 19 mars 2015, arrêt n°39/2015: Demandeurs d'asile et aide matérielle

  Flohimont, V., 2018, In: Revue trimestrielle de Droit familial. 2017, 4, p. 925-927 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Note sous Cour constitutionnelle, 6 juillet 2017, n° 90/2017: allocations familiales et placement en institution

  Flohimont, V., 2018, In: Revue trimestrielle de Droit familial. 1, p. 196-198

  Research output: Contribution to journal › Article

  Open Access

  File
  2 Downloads (Pure)

• Recrutement 2.0: le facteur humain avant la technologie

  Weerts, F., Flohimont, V., Van Hemelrijck, M., Landré, H., Van Aart, F. & de Moerloose, R., 29 Jan 2018, RH Magazine, 248, p. 18-22.

  Research output: Contribution to specialist publication › Article

  Open Access

  File
  3 Downloads (Pure)
• 2017

  An optimized dRVVT-based assay to estimate the intensity of anticoagulation in patients treated with direct oral anticoagulants

  Sennesael, A-L., Exner, T., Chatelain, B., Lessire, S., Larock, A-S., Vancraeynest, C., Pochet, L., Dogné, J-M., Spinewine, A., Mullier, F. & Douxfils, J., 1 Sep 2017, In: Thrombosis Research. 157, p. 29-37 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Prothrombin Time
  • Anticoagulants
  • apixaban
  • Dabigatran
  • Rivaroxaban

• Cassation, 19 janvier 2015, note 'allocations familiales et revenu d'intégration sociale - calcul des ressources'

  Flohimont, V., 2017, In: Revue trimestrielle de Droit familial. 4/2016, p. 1106-1108

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Downloads (Pure)

• Development and evaluation of injectable nanosized drug delivery systems for apigenin

  Reatul, K., Palazzo, C., Laloy, J., Delvigne, A-S., Vanslambrouck, S., Jérôme, C., Lepeltier, E., Orange, F., Dogne, J-M., Evrard, B., Passirani, C. & Piel, G., 5 Nov 2017, In: International Journal of Pharmaceutics. 532, 2, p. 757-768 12 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Nanocapsules
  • Apigenin
  • Drug Delivery Systems
  • Injections
  • Liposomes
  39 Downloads (Pure)

• Eculizumab decreases the procoagulant activity of extracellular vesicles in paroxysmal nocturnal hemoglobinuria: A pilot prospective longitudinal clinical study.

  Wannez, A., Devalet, B., Bouvy, C., Laloy, J., Bihin, B., Chatelain, B., Chatelain, C., Dogne, J-M. & Mullier, F., 1 Aug 2017, In: Thrombosis Research. 156, p. 142-148 7 p.

  Research output: Contribution to journal › Article › peer-review

  • eculizumab
  • Paroxysmal Hemoglobinuria
  • Extracellular Vesicles
  • Longitudinal Studies
  • Clinical Studies

• Etayer les enfants vulnérabilisés par le harcèlement entre pairs en milieu scolaire

  Piquet, E. & Flohimont, V., 17 Jun 2017, In: Recherches & Éducations. 17, 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Procoagulant activity of extracellular vesicles as a potential biomarker for risk of thrombosis and DIC in patients with acute leukaemia

  Gheldof, D., Haguet, H., Dogne, J-M., Bouvy, C., Graux, C., George, F., Sonet, A., Chatelain, C., Chatelain, B. & Mullier, F., 1 Feb 2017, In: Journal of Thrombosis and Thrombolysis. 43, 2, p. 224-232 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Vesicles
  • Disseminated Intravascular Coagulation
  • Leukemia
  • Thrombosis
  • Biomarkers

• Study of extracellular vesicles roles in the pathophysiology of thrombosis in paroxysmal nocturnal hemoglobinuria patients during eculizumab treatment: A pilot prospective longitudinal clinical study

  Wannez, A., Devalet, B., Bouvy, C., Bihin, B., Dogne, J. M. & Mullier, F., 2017, In: Acta haematologica. 102, p. 62

  Research output: Contribution to journal › Article › peer-review

  • eculizumab
  • Paroxysmal Hemoglobinuria
  • Extracellular Vesicles
  • Longitudinal Studies
  • Thrombosis

• Vascular safety profile of new generation BCR-ABL tyrosine kinase inhibitors in the treatment of chronic myeloid leukaemia

  Haguet, H., Douxfils, J., Mullier, F., Chatelain, C., Graux, C. & Dogne, J-M., Mar 2017, In: Belgian Journal of Hematology Volume. 8, 2, p. 45-52 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Protein-Tyrosine Kinases
  • ponatinib
  • Dasatinib
• 2016

  Cass., 18 novembre 2013, note "allocations d’intégration pour personne handicapée – notion de ménage"

  Flohimont, V., Jan 2016, In: Revue trimestrielle de Droit familial. 4/2015, p. 1003-1004

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Downloads (Pure)

• Coup d’oeil sur les pensions de retraite au travers de l’histoire de la sécurité sociale: Partie 3. Les pensions de retraite

  Flohimont, V., Jun 2016, In: InfoPensions. 2016/14, p. 8-12

  Research output: Contribution to journal › Article

  Open Access

  File
  1 Downloads (Pure)

• Coup d’oeil sur les pensions de retraite au travers de l’histoire de la sécurité sociale: Partie 4. Conclusions

  Flohimont, V., Sep 2016, In: InfoPensions. 2016/15, p. 7-8

  Research output: Contribution to journal › Article

  Open Access

  File
  2 Downloads (Pure)

• Coup d’œil sur les pensions de retraite au travers de l’histoire de la sécurité sociale: Partie 2. L’assurance maladie-invalidité

  Flohimont, V., Mar 2016, In: InfoPensions. 2016/13, p. 9-13

  Research output: Contribution to journal › Article

  Open Access

  File
  1 Downloads (Pure)

• Cour constitutionnelle, 10 mars 2016, note 'allocations familiales garanties et aide sociale'

  Flohimont, V., 2016, In: Revue trimestrielle de Droit familial. 2016/2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Cour constitutionnelle, 26 septembre 2013, note « allocations familiales – concours d’attributaires appartenant à des régimes différents »

  Flohimont, V., Jan 2016, In: Revue trimestrielle de Droit familial. 4/2015, p. 1002

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Cour constitutionnelle, 3 décembre 2015, note « revenu d’intégration sociale – notion de cohabitant et d’isolé »

  Flohimont, V., 2016, In: Revue trimestrielle de Droit familial. 2016/1, p. 205-207

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Downloads (Pure)

• Een blik op de rustpensioenen doorheen de geschiedenis van de sociale zekerheid: Deel 3. De rustpensioenen

  Flohimont, V., Jun 2016, In: InfoPensioenen. 2016/14, p. 8-12

  Research output: Contribution to journal › Article

  Open Access

  File
  2 Downloads (Pure)

• Een blik op de rustpensioenen doorheen de geschiedenis van de sociale zekerheid: Deel 2. De ziekte- en invaliditeitsverzekering

  Flohimont, V., Mar 2016, In: InfoPensioenen. 2016/13, p. 9-13

  Research output: Contribution to journal › Article

  Open Access

  File
  3 Downloads (Pure)

• Een blik op de rustpensioenen doorheen de geschiedenis van de sociale zekerheid: Deel 4. Conclusies

  Flohimont, V., Sep 2016, In: InfoPensioenen. 2016/15, p. 7-8

  Research output: Contribution to journal › Article

  Open Access

  File
  1 Downloads (Pure)

• Hyaluronidase 1 deficiency preserves endothelial function and glycocalyx integrity in early streptozotocin-induced diabetes

  Dogné, S., Rath, G., Jouret, F., Caron, N., Dessy, C. & Flamion, B., 1 Sep 2016, In: Diabetes. 65, 9, p. 2742-2753 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Hyaluronidase Deficiency
  • Glycocalyx
  • Experimental Diabetes Mellitus
  • Hyaluronic Acid
  • Vasodilation

• Meta-analysis of the risks of arterial and venous occlusive events with new generation BCR-ABL TKIs in patients with chronic myeloid leukaemia

  Haguet, H., Douxfils, J., Mullier, F., Chatelain, C., Graux, C. & Dogne, J-M., 2016, In: Haematologica : The hematology journal. 101, s1, p. 452-453

  Research output: Contribution to journal › Article › peer-review

• Multimodality imaging assessment of the deleterious role of the intraluminal thrombus on the growth of abdominal aortic aneurysm in a rat model

  Nchimi, A., Courtois, A., El Hachemi, M., Touat, Z., Drion, P., Withofs, N., Warnock, G., Bahri, M. A., Dogne, J-M., Cheramy-Bien, J. P., Schoysman, L., Joskin, J., Michel, J. B., Defraigne, J. O., Plenevaux, A. & Sakalihasan, N., 1 Jul 2016, In: European Radiology. 26, 7, p. 2378-2386 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Abdominal Aortic Aneurysm
  • Thrombosis
  • Deoxyglucose
  • Growth
  • Magnetic Resonance Imaging

• Profilage: Analyser les données de consommation de tous les Belges pour lutter contre la fraude sociale? Mauvaise idée!

  Flohimont, V., Neven, J-F. & Dumont, D., 1 Mar 2016, La libre Belgique.

  Research output: Contribution to specialist publication › Article

  Open Access

  File
  1 Downloads (Pure)

• Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors

  Bouckaert, C., Serra, S., Rondelet, G., Dolusic, E., Wouters, J., Dogne, J-M., Frédérick, R. & Pochet, L., 3 Mar 2016, In: European Journal of Medicinal Chemistry. p. 181-194 14 p., 110.

  Research output: Contribution to journal › Article › peer-review

  • factor XIIa inhibitor
  • Factor XIIa
  • Coumarins
  • Structure-Activity Relationship
  • Enzyme Precursors
• 2015

  Cassation, 24 novembre 2014, note 'revenu d'intégration sociale et allocations familiales'

  Flohimont, V., 2015, In: Revue trimestrielle de Droit familial. 2015, 2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Downloads (Pure)

• Coup d’œil sur les pensions de retraite au travers de l’histoire de la sécurité sociale: Partie 1.

  Flohimont, V., Dec 2015, In: InfoPensions. 2015/12, p. 11-17

  Research output: Contribution to journal › Article

  Open Access

  File
  1 Downloads (Pure)

• Cour constitutionnelle, 23 octobre 2014, note 'allocations familiales et étrangers'

  Flohimont, V., 2015, In: Revue trimestrielle de Droit familial. 1/2015, p. 120 121 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Deficiency in mouse hyaluronidase 2: A new mechanism of chronic thrombotic microangiopathy

  Onclinx, C., Dogne, S., Jadin, L., Andris, F., Grandfils, C., Jouret, F., Mullier, F. & Flamion, B., 5 Aug 2015, In: Acta haematologica. 100, 8, p. 1023-1030 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Thrombotic Microangiopathies
  • Hyaluronoglucosaminidase
  • Hyaluronic Acid
  • Erythrocytes
  • Hyaluronidase Deficiency

• Dose tailoring of dabigatran etexilate: Obvious or excessive?

  Douxfils, J., Mullier, F. & Dogné, J. M., 1 Aug 2015, In: Expert Opinion On Drug Safety. 14, 8, p. 1283-1289 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dabigatran
  • Risk Assessment
  • Expert Testimony
  • Causality
  • Anticoagulants
  23 Downloads (Pure)

• Een blik op de ouderdomspensioenen doorheen de geschiedenis van de sociale zekerheid: Deel 1.

  Flohimont, V., Dec 2015, In: InfoPensioenen. 2015/12, p. 11-17

  Research output: Contribution to journal › Article

  Open Access

  File
  2 Downloads (Pure)

• Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL

  Souza, P. S., Madigan, J. P., Gillet, J. P., Kapoor, K., Ambudkar, S. V., Maia, R. C., Gottesman, M. M. & Leung Fung, K., 15 Aug 2015, In: Experimental Cell Research. 336, 2, p. 318-328 11 p.

  Research output: Contribution to journal › Article › peer-review

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Apoptosis
  • Multiple Drug Resistance
  • Doxycycline
  • Tetracycline

• Hyaluronidase-1 is Mainly Functional in the Upper Granular Layer, Close to the Epidermal Barrier

  Malaisse, J., Evrard, C., Feret, D., Colombaro, V., Dogné, S., Haftek, M., de Rouvroit, C. L., Flamion, B. & Poumay, Y., 1 Dec 2015, In: The journal of investigative dermatology. 135, 12, p. 3189-3192 4 p.

  Research output: Contribution to journal › Article › peer-review
  8 Downloads (Pure)

• Kinderbijslag: de uitdagingen halverwege de overdracht

  Flohimont, V. & Neven, J-F., 6 Dec 2015, In: Belgisch Tijdschrift voor sociale zekerheid. p. 229-268

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  3 Downloads (Pure)

• Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

  Colombaro, V., Jadot, I., Declèves, A. E., Voisin, V., Giordano, L., Habsch, I., Malaisse, J., Flamion, B. & Caron, N., 2 Jul 2015, In: Kidney international. 88, 1, p. 61-71 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hyaluronoglucosaminidase
  • Hyaluronic Acid
  • Fibrosis
  • Reperfusion Injury
  • Inflammation