Mass Spectrometry Service

Facility/equipment: Technological Platform

  • Location

    Belgium

Equipments Details

Description

DESCRIPTION

The University of Namur Mass Spectrometry platform (MaSUN) involves equipment from different research units ofthe departments of Pharmacy, Chemistry and Biology. Our aim is to provide support in mass spectrometry, proteomicsanalyses, gel electrophoresis to the UNamur students and staff. Our facility is also open to collaborate with otheruniversities and public or private laboratories.

EXPERTISE

Identification and characterization of small molecules.

Targeted compounds quantification (biomarkers, drugs...).

Proteomics analyses (gel-free or gel-dependent, label-free quantification).

Peptidomics (profile analyses).

Two dimensional HPLC (2D-LC).

Gel electrophoresis including 2D-DIGE.

EQUIPMENT

MASS SPECTROMETERS

• LC-MS

• UPLC-MSMS Xevo TQ-S (Waters)

• High resolution nanoRSLC-MSMSmaXis Impact (Bruker)

• Characterization of small molecules

• Biomarker and drug quantification

• Protein identification in complexsamples

GEL-DEPENDENT PROTEOMICS

• ELECTROPHORESIS

• TYPHOON CONFOCAL SCANNERand SPOT PICKER ROBOT

• DECYDER software

• 2D Ettan Dalt electrophoresisdevice

• For fluorescence-labelled 2D gels

• 2D-DIGE image analysis

GEL-FREE PROTEOMICS

• High resolution nanoRSLC-MSMS

• 2D-LC

• Mascot, Scaffold, Progenesis QIsoftwares

• Protein identification in complexmixtures

• Two dimensional HPLC separation

• Proteomics data analysis andquantification

Fingerprint Explore the research areas in which this equipment has been used. These labels are generated based on the related outputs. Together they form a unique fingerprint.

  • Research Output

    Comparative study of concatemer efficiency as an isotope-labelled internal standard for allergen quantification

    Gavage, M., Van Vlierberghe, K., Van Poucke, C., De Loose, M., Gevaert, K., Dieu, M., Renard, P., Arnould, T., Filee, P. & Gillard, N., 27 Jun 2020, In : Food Chemistry . 332, p. 1-10 10 p., 127413.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Downloads (Pure)

    High-resolution mass spectrometry-based selection of peanut peptide biomarkers considering food processing and market type variation

    Gavage, M., Van Vlierberghe, K., Van Poucke, C., De Loose, M., Gevaert, K., Dieu, M., Renard, P., Arnould, T. & Gillard, N., 30 Jan 2020, In : Food Chemistry . 304, p. 125428 10 p., 125428.

    Research output: Contribution to journalArticle

  • Optimization of label-free nano LC-MS/MS analysis of the placental proteome

    Luyten, L. J., Dieu, M., Demazy, C., Fransolet, M., Nawrot, T. S., Renard, P. & Debacq-Chainiaux, F., 10 Nov 2020, In : Placenta. 101, p. 159-162 4 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Downloads (Pure)

    Projects

    Activities

    • 1 Participation to a Symposium, a study Day

    Symposium on Food Allergens: regulation, management and detection

    Thierry Arnould (Poster)

    17 Sep 2015

    Activity: Participating in or organising an event typesParticipation to a Symposium, a study Day