Research output per year
Research output per year
- 1 - 50 out of 121 results
Search results
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2024
Genome-wide analysis of Brucella melitensis growth in spleen of infected mice allows rational selection of new vaccine candidates
Barbieux, E., Potemberg, G., Stubbe, F.-X., Fraikin, A., Poncin, K., Reboul, A., Rouma, T., Zúñiga-Ripa, A., De Bolle, X. & Muraille, E., 1 Aug 2024, In: Plos Pathogens. 20, 8 August, p. e1012459 e1012459.Research output: Contribution to journal › Article › peer-review
Open Access -
Post-transcriptional control of the essential enzyme MurF by a small regulatory RNA in Brucella abortus
King, K. A., Benton, A. H., Caudill, M. T., Stoyanof, S. T., Kang, L., Michalak, P., Lahmers, K. K., Dunman, P. M., DeHart, T. G., Ahmad, S. S., Jutras, B. L., Poncin, K., De Bolle, X. & Caswell, C. C., Jan 2024, In: Molecular Microbiology. 121, 1, p. 129-141 13 p., 10.1111/mmi.15207.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Host cell egress of Brucella abortus requires BNIP3L-mediated mitophagy
Verbeke, J., Fayt, Y., Martin, L., Yilmaz, O., Sedzicki, J., Reboul, A., Jadot, M., Renard, P., Dehio, C., Renard, H. F., Letesson, J.-J., De Bolle, X. & Arnould, T., 17 Jul 2023, In: The EMBO journal. 42, 14, e112817.Research output: Contribution to journal › Article › peer-review
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Lipopolysaccharide biosynthesis and traffic in the envelope of the pathogen Brucella abortus
Servais, C., Vassen, V., Verhaeghe, A., Küster, N., Carlier, E., Phégnon, L., Mayard, A., Auberger, N., Vincent, S. & De Bolle, X., 17 Feb 2023, In: Nature Communications. 14, 1, p. 911 911.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Downloads (Pure) -
Vaccine properties of Brucella melitensis 16MΔwzm and reactivation of placental infection in pregnant sheep
Zabalza-Baranguá, A., Poveda-Urkixo, I., Mena-Bueno, S., Ramírez, G. A., De Bolle, X. & Grilló, M. J., 24 Feb 2023, In: Vaccine. 41, 9, p. 1554-1566 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Viral entry inhibitors protect against SARS-CoV-2-induced neurite shortening in differentiated SH-SY5Y cells
MIGNOLET, M., Gilloteaux, J., Halloin, N., Gueibe, M., Willemart, K., De Swert, K., Bielarz, V., Suain, V., Pastushenko, I., Gillet, N. & Nicaise, C., Oct 2023, In: Viruses. 15, 10, 2020.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
When mitophagy dictates the outcome of cellular infection: the case of Brucella abortus
Verbeke, J., De Bolle, X. & Arnould, T., 2023, In: Autophagy. 19, 11, p. 3022-3023 2 p.Research output: Contribution to journal › Article › peer-review
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2022
Genome-wide analysis of Brucella melitensis genes required throughout intranasal infection in mice
Potemberg, G., Demars, A., Barbieux, E., Reboul, A., Stubbe, F. X., Galia, M., Lagneaux, M., Comein, A., Denis, O., Pérez-Morga, D., Vanderwinden, J. M., De Bolle, X. & Muraille, E., Jun 2022, In: Plos Pathogens. 18, 6, e1010621.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Downloads (Pure) -
Histidine auxotroph mutant is defective for cell separation and allows the identification of crucial factors for cell division in Brucella abortus
Roba, A., Carlier, E., Godessart, P., Naili, C. & De Bolle, X., 24 Jun 2022, In: Molecular Microbiology. 118, 3, p. 145-154 10 p.Research output: Contribution to journal › Article › peer-review
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Identification of SARS-CoV-2 Neutralizing Antibody with Pseudotyped Virus-based Test on HEK-293T hACE2 Cells
Gillot, C., Favresse, J., Maloteau, V., Dogné, J.-M. & Douxfils, J., 5 Apr 2022, In: Bio-protocol. 12, 7, p. e4377 e4377.Research output: Contribution to journal › Article › peer-review
Open AccessFile56 Downloads (Pure) -
2021
Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice
Demars, A., Vitali, A., Comein, A., Carlier, E., Azouz, A., Goriely, S., Smout, J., Flamand, V., Van Gysel, M., Wouters, J., Abendroth, J., Edwards, T. E., Machelart, A., Hoffmann, E., Brodin, P., De Bolle, X. & Muraille, E., Sept 2021, In: Plos Pathogens. 17, 9, p. e1009887 e1009887.Research output: Contribution to journal › Article › peer-review
Open AccessFile100 Downloads (Pure) -
PdeA is required for the rod shape morphology of Brucella abortus
Reboul, A., Carlier, E., Stubbe, F. X., Barbieux, E., Demars, A., Ong, P. T. A., Gerodez, A., Muraille, E. & De Bolle, X., Dec 2021, In: Molecular Microbiology. 116, 6, p. 1449-1463 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Downloads (Pure) -
Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection
Bielarz, V., WILLEMART, K., Avalosse, N., De Swert, K., Lotfi, R., Lejeune, N., Poulain, F., Ninanne, N., Gilloteaux, J., GILLET, N. & Nicaise, C., 1 May 2021, In: Brain research. 1758, 147344.Research output: Contribution to journal › Article › peer-review
Open AccessFile58 Downloads (Pure) -
β-Barrels covalently link peptidoglycan and the outer membrane in the α-proteobacterium Brucella abortus
Godessart, P., Lannoy, A., Dieu, M., Van der Verren, S. E., Soumillion, P., Collet, J.-F., Remaut, H., Renard, P. & De Bolle, X., Jan 2021, In: Nature Microbiology. 6, 1, p. 27-33 7 p.Research output: Contribution to journal › Article › peer-review
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2020
Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway
Machelart, A., Willemart, K., Zúñiga-Ripa, A., Godard, T., Plovier, H., Wittmann, C., Moriyón, I., De Bolle, X., Van Schaftingen, E., Letesson, J.-J. & Barbier, T., 20 Oct 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 42, p. 26374-26381 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Downloads (Pure) -
Intracellular Growth and Cell Cycle Progression are Dependent on (p)ppGpp Synthetase/Hydrolase in Brucella abortus
Van der Henst, M., Carlier, E. & De Bolle, X., 14 Jul 2020, In: Pathogens. 9, 7, p. 1-13 13 p., 571.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Downloads (Pure) -
Shedding of Brucella melitensis happens through milk macrophages in the murine model of infection
Jansen, W., Demars, A., Nicaise, C., Godfroid, J., De Bolle, X., Reboul, A. & Al Dahouk, S., 10 Jun 2020, In: Scientific Reports. 10, 1, 9421.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Localized incorporation of outer membrane components in the pathogen Brucella abortus
Vassen, V., Valotteau, C., Feuillie, C., Formosa-Dague, C., Dufrêne, Y. F. & De Bolle, X., 1 Mar 2019, In: The EMBO journal. 38, 5, e100323.Research output: Contribution to journal › Article › peer-review
Open Access -
Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
Poncin, K., Roba, A., Jimmidi, R., Potemberg, G., Fioravanti, A., Francis, N., Willemart, K., Zeippen, N., Machelart, A., Biondi, E. G., Muraille, E., Vincent, S. P. & De Bolle, X., 24 Oct 2019, In: Nature Communications. 10, 1, p. 4847 4847.Research output: Contribution to journal › Article › peer-review
Open AccessFile55 Downloads (Pure) -
Route of Infection Strongly Impacts the Host-Pathogen Relationship
Demars, A., Lison, A., Machelart, A., Van Vyve, M., Potemberg, G., Vanderwinden, J.-M., De Bolle, X., Letesson, J.-J. & Muraille, E., 1 Jan 2019, In: Frontiers in Immunology. 10, JULY, p. 1589 23 p., 1589.Research output: Contribution to journal › Article › peer-review
Open AccessFile58 Downloads (Pure) -
2018
3D correlative electron microscopy reveals continuity of Brucellacontaining vacuoles with the endoplasmic reticulum
Sedzicki, J., Tschon, T., Low, S. H., Willemart, K., Goldie, K. N., Letesson, J.-J., Stahlberg, H. & Dehio, C., 1 Feb 2018, In: Journal of Cell Science. 131, 4, jcs210799.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Downloads (Pure) -
Learning from the master: Targets and functions of the CtrA response regulator in Brucella abortus and other alpha-proteobacteria
Poncin, K., Gillet, S. & De Bolle, X., 1 Jul 2018, In: FEMS microbiology reviews. 42, 4, p. 500-513 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria
Lobet, E., Willemart, K., Ninane, N., Demazy, C., Sedzicki, J., Lelubre, C., De Bolle, X., Renard, P., Raes, M., Dehio, C., Letesson, J. J. & Arnould, T., 26 Mar 2018, In: Scientific Reports. 8, 1, p. 1-17 17 p., 5173.Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Downloads (Pure) -
Transposon sequencing of Brucella abortus uncovers essential genes for growth in vitro and inside macrophages
Sternon, J.-F., Godessart, P., Gonçalves de Freitas, R., Van der Henst, M., Poncin, K., Francis, N., Willemart, K., Christen, M., Christen, B., Letesson, J.-J. & De Bolle, X., 1 Aug 2018, In: Infection and Immunity. 86, 8, e00312-18.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen
Machelart, A., Khadrawi, A., Demars, A., Willemart, K., De Trez, C., Letesson, J.-J. & Muraille, E., Nov 2017, In: Infection and Immunity. 85, 11, e00115-17.Research output: Contribution to journal › Article › peer-review
Open Access -
CtrA Controls Cell Division and Outer Membrane Composition of the Pathogen Brucella abortus
Francis, N., Poncin, K., Fioravanti, A., Vassen, V., Willemart, K., Ong, T. A. P., Rappez, L., Letesson, J.-J., Biondi, E. G. & De Bolle, X., Mar 2017, In: Molecular Microbiology. 103, 5, p. 780-797 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Erythritol availability in bovine, murine and human models highlights a potential role for the host aldose reductase during Brucella infection
Barbier, T., Machelart, A., Zúñiga-Ripa, A., Plovier, H., Hougardy, C., Lobet, E., Willemart, K., Muraille, E., De Bolle, X., Van Schaftingen, E., Moriyón, I. & Letesson, J. J., 13 Jun 2017, In: Frontiers in Microbiology. 8, JUN, p. 1088 1088.Research output: Contribution to journal › Article › peer-review
Open AccessFile93 Downloads (Pure) -
Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection
Bruffaerts, N., Vluggen, C., Roupie, V., Duytschaever, L., Van den Poel, C., Denoël, J., Wattiez, R., Letesson, J. J., Fretin, D., Rigouts, L., Chapeira, O., Mathys, V., Saegerman, C. & Huygen, K., 1 Feb 2017, In: PLoS ONE. 12, 2, e0171895.Research output: Contribution to journal › Article › peer-review
Open AccessFile115 Downloads (Pure) -
2016
Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains
Suárez-Esquivel, M., Ruiz-Villalobos, N., Castillo-Zeledón, A., Jiménez-Rojas, C., Roop, R. M., Comerci, D. J., Barquero-Calvo, E., Chacón-Díaz, C., Caswell, C. C., Baker, K. S., Chaves-Olarte, E., Thomson, N. R., Moreno, E., Letesson, J. J., De Bolle, X. & Guzmán-Verri, C., 2016, In: Frontiers in Microbiology. 7, SEPResearch output: Contribution to journal › Article › peer-review
Open AccessFile103 Downloads (Pure) -
Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice
Hanot Mambres, D., Machelart, A., Potemberg, G., De Trez, C., Ryffel, B., Letesson, J.-J. & Muraille, E., 2016, In: Journal of immunology. 196, 9, p. 3780-93 14 p.Research output: Contribution to journal › Article › peer-review
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Metabolic control of cell division in α-proteobacteria by a NAD-dependent glutamate dehydrogenase
Beaufay, F., De Bolle, X. & Hallez, R., 2016, In: Communicative and Integrative Biology. 9, 1Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Brucella abortus Cell Cycle and Infection Are Coordinated
De Bolle, X., Crosson, S., Matroule, J.-Y. & Letesson, J.-J., 2015, In: Trends in Microbiology.Research output: Contribution to journal › Article › peer-review
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In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice
Hanot Mambres, D., Machelart, A., Vanderwinden, J.-M., De Trez, C., Ryffel, B., Letesson, J.-J. & Muraille, E., 2015, In: PLoS ONE. 10, 9, p. e0137835Research output: Contribution to journal › Article › peer-review
Open AccessFile70 Downloads (Pure) -
Mitochondria : A target for bacteria
Lobet, E., Letesson, J.-J. & Arnould, T., 1 Apr 2015, In: Biochemical Pharmacology. 94, 3, p. 173-185 13 p.Research output: Contribution to journal › Article › peer-review
File511 Downloads (Pure) -
2014
Brucella, nitrogen and virulence
Ronneau, S., Moussa, S., Barbier, T., Conde-Álvarez, R., Zuniga-Ripa, A., Moriyon, I. & Letesson, J.-J., 2014, In: Critical Reviews in Microbiology. p. 1-19 19 p.Research output: Contribution to journal › Article › peer-review
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Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1,6-bisphosphatases for full virulence in laboratory models
Zúñiga-Ripa, A., Barbier, T., Conde-Álvarez, R., Martínez-Gómez, E., Palacios-Chaves, L., Gil-Ramírez, Y., Grilló, M. J., Letesson, J.-J., Iriarte, M. & Moriyón, I., 2014, In: Journal of Bacteriology.Research output: Contribution to journal › Article › peer-review
File199 Downloads (Pure) -
Brucella melitensis invades murine erythrocytes during infection
Vitry, M.-A., Hanot-Mambres, D., Deghelt, M., Hack, K., Machelart, A., Lhomme, F., Vanderwinden, J.-M., Vermeersch, M., De Trez, C., Pérez-Morga, D., Letesson, J.-J. & Muraille, E., 2014, In: Infection and Immunity. 82, 9, p. 3927-3938 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile114 Downloads (Pure) -
Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella
Barbier, T., Collard, F., Zúñiga-Ripa, A., Moriyón, I., Godard, T., Becker, J., Wittmann, C., Van Schaftingen, E. & Letesson, J.-J., 16 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 50, p. 17815-17820 6 p.Research output: Contribution to journal › Article › peer-review
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G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus
Deghelt, M., Mullier, C., Sternon, J.-F., Francis, N., Laloux, G., Dotreppe, D., Van der Henst, C., Jacobs-Wagner, C., Letesson, J.-J. & De Bolle, X., 2014, In: Nature Communications. 5, p. 4366 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile103 Downloads (Pure) -
Insights into the function of YciM, a heat shock membrane protein required to maintain envelope integrity in escherichia coli
Nicolaes, V., Hajjaji, H. E., Davis, R. M., Van der Henst, C., Depuydt, M., Leverrier, P., Aertsen, A., Haufroid, V., de Choudens, S. O., De Bolle, X., Ruiz, N. & Collet, J. F., 1 Jan 2014, In: Journal of Bacteriology. 196, 2, p. 300-309 10 p.Research output: Contribution to journal › Article › peer-review
4 Downloads (Pure) -
On the link between cell cycle and infection of the Alphaproteobacterium Brucella abortus
Letesson, J.-J., De Bolle, X. & Deghelt, M., 2014, In: microbial cell. 1, 10, p. 346-348Research output: Contribution to journal › Article › peer-review
Open Access -
Replication of Brucella abortus and Brucella melitensis in fibroblasts does not require Atg5-dependent macroautophagy
Hamer, I., Goffin, E., De Bolle, X., Letesson, J.-J. & Jadot, M., 2 Sept 2014, In: BMC microbiology. 14, 1, 14.Research output: Contribution to journal › Article › peer-review
Open AccessFile88 Downloads (Pure) -
The quest for a true One Health perspective of brucellosis
Godfroid, J., De Bolle, X., Roop, R. M., O'Callaghan, D., Tsolis, R. M., Baldwin, C., Santos, R. L., McGiven, J., Olsen, S., Nymo, I. H., Larsen, A., Al Dahouk, S. & Letesson, J. J., Aug 2014, In: Revue scientifique et technique (International Office of Epizootics). 33, 2, p. 521-538 18 p.Research output: Contribution to journal › Article › peer-review
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2013
Brucella melitensis MucR, an orthologue of Sinorhizobium meliloti MucR, is involved in resistance to oxidative, detergent, and saline stresses and cell envelope modifications
Mirabella, A., Terwagne, M., Zygmunt, M. S., Cloeckaert, A., De Bolle, X. & Letesson, J. J., 1 Feb 2013, In: Journal of Bacteriology. 195, 3, p. 453-465 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile100 Downloads (Pure) -
BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions
Salcedo, S. P., Marchesini, M. I., Degos, C., Terwagne, M., Von Bargen, K., Lepidi, H., Herrmann, C. K., Santos Lacerda, T. L., Imbert, P. R. C., Pierre, P., Alexopoulou, L., Letesson, J.-J., Comerci, D. J. & Gorvel, J.-P., 2013, In: Frontiers in cellular and infection microbiology. 3, p. 28Research output: Contribution to journal › Article › peer-review
Open AccessFile155 Downloads (Pure) -
Innate immune recognition of flagellin limits systemic persistence of Brucella
Terwagne, M., Ferooz, J., Rolán, H. G., Sun, Y. H., Atluri, V., Xavier, M. N., Franchi, L., Núñez, G., Legrand, T., Flavell, R. A., De Bolle, X., Letesson, J.-J. & Tsolis, R. M., 1 Jun 2013, In: Cellular microbiology. 15, 6, p. 942-960 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Downloads (Pure) -
Quorum sensing and self-quorum quenching in the intracellular pathogen Brucella melitensis
Terwagne, M., Mirabella, A., Lemaire, J., Deschamps, C., De Bolle, X. & Letesson, J.-J., 11 Dec 2013, In: PLoS ONE. 8, 12, e82514.Research output: Contribution to journal › Article › peer-review
Open AccessFile132 Downloads (Pure) -
The Brucella pathogens are polarized bacteria
Van der Henst, C., de Barsy, M., Zorreguieta, A., Letesson, J.-J. & De Bolle, X., 1 Dec 2013, In: Microbes and infection : a journal on infectious agents and host defenses. 15, 14-15, p. 998-1004 7 p.Research output: Contribution to journal › Article › peer-review
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2012
A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells
de Barsy, M., Mirabella, A., Letesson, J.-J. & De Bolle, X., 2012, In: Microbiology. 158, Pt 10, p. 2610-8 9 p.Research output: Contribution to journal › Article › peer-review
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Crucial Role of Gamma Interferon-Producing CD4+ Th1 Cells but Dispensable Function of CD8+ T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice
Vitry, M.-A., De Trez, C., Goriely, S., Dumoutier, L., Akira, S., Ryffel, B., Carlier, Y., Letesson, J.-J. & Muraille, E., 2012, In: Infection and Immunity. 80, 12, p. 4271-80 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile80 Downloads (Pure)