Heterocycles in Bio-organic Chemistry

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• Broadening TDO's base

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• Student theses

• Caractérisation enzymatique et structurale d'inhibiteurs indoliques de la tryptophane 2,3-dioxygénase. Mémoire présenté pour l'obtention du grade académique de Master en Chimie "Chimie du Vivant et des Nanomatériaux" : Finalité Spécialisée.

  Student thesis: Master types › Master in Chemistry

• Synthèse d'inhibiteurs d'indoleamine-2,3-dioxygenases (IDO et TDO) deux enzymes dont les propriétés immunosuppressives en font des cibles majeures pour le traitement du cancer

  Student thesis: Master types › Master in Chemistry

• Projects

• tryptophane 2,3-dioxygénase

  Project: Research

• Design, synthesis and study of enzyme modulators implicated in tryptophan metabolism and particularly in the kynurenin pathway

  Project: Research

• Research output

• Tryptophan 2,3-dioxygenase (TDO) inhibitors : Identification of new scaffolds using virtual screening

  Research output: Contribution to conference › Poster

• Tryptophan 2,3-dioxygenase (TDO) inhibitors : Identification of new scaffolds using virtual screening

  Research output: Contribution to conference › Poster

• Conception, synthèse et étude d'inhibiteurs de la tryptophane 2,3-dioxygénase (TDO), une cible prometteuse pour le traitement du cancer

  Research output: Contribution to conference › Poster

• THIOSEMICARBAZONES AS INHIBITORS OF TRYPTOPHAN 2,3-DIOXYGENASE (TDO), AN EMERGING TARGET FOR CANCER TREATMENT

  Research output: Contribution to conference › Poster

• Synthesis, crystal and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles

  Research output: Contribution to conference › Poster

• 3-ALKENYL INDOLES AS TRYPTOPHAN 2,3-DIOXYGENASE INHIBITORS FOR THE ENHANCEMENT OF CANCER IMMUNOTHERAPY

  Research output: Contribution to conference › Poster › peer-review

• Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

  Research output: Contribution to journal › Literature review › peer-review

• Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles

  Research output: Contribution to journal › Article › peer-review

• Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

  Research output: Contribution to journal › Article › peer-review

• Tryptophan 2,3-Dioxygenase (TDO) Inhibitors as Anticancer Immunomodulators

  Research output: Contribution to conference › Poster

• Structural and enzymatic study of tryptophan 2,3-dioxgenase (TDO), a potential target in anticancer immunotherapy.

  Research output: Contribution to journal › Literature review › peer-review

• Structural and enzymatic study of tryptophan 2.3-dioxygenase (TDO), a potential target in anticancer immunotherapy

  Research output: Contribution to conference › Paper

• Synthesis, structural, enzymatic and cellular studies of vinyl-1H-indole analogues as potential inhibitors of tryptophan 2,3-dioxygenase (TDO), an attractive target in cancer immunotherapy.

  Research output: Contribution to conference › Poster

• Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators

  Research output: Contribution to journal › Article › peer-review

• Design, synthesis and study of inhibitors of tryptophan 2,3-dioxygenase (TDO), a promising target for cancer therapy

  Research output: Contribution to conference › Poster

• SYNTHESIS, ACTIVITY, CRYSTAL AND ELECTRONIC PROPERTIES OF ISOMERS OF CHLORO-PYRIDINYLVINYL-1H-INDOLES

  Research output: Contribution to conference › Poster

• coauthor on lecture: Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase (TDO): discovery of an orally active TDO inhibitor.

  Research output: Contribution in Book/Catalog/Report/Conference proceeding › Conference contribution